JPH10513057A - 組換えα−ガラクトシダーゼ酵素 - Google Patents

組換えα−ガラクトシダーゼ酵素

Info

Publication number
JPH10513057A
JPH10513057A JP8523663A JP52366396A JPH10513057A JP H10513057 A JPH10513057 A JP H10513057A JP 8523663 A JP8523663 A JP 8523663A JP 52366396 A JP52366396 A JP 52366396A JP H10513057 A JPH10513057 A JP H10513057A
Authority
JP
Japan
Prior art keywords
galactosidase
coffee bean
enzyme
recombinant
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP8523663A
Other languages
English (en)
Japanese (ja)
Inventor
ズー、アレックス
ゴールドスタイン、ジャック
Original Assignee
ニューヨーク・ブラッド・センター・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ニューヨーク・ブラッド・センター・インコーポレイテッド filed Critical ニューヨーク・ブラッド・センター・インコーポレイテッド
Publication of JPH10513057A publication Critical patent/JPH10513057A/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
JP8523663A 1995-01-30 1996-01-30 組換えα−ガラクトシダーゼ酵素 Ceased JPH10513057A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38019495A 1995-01-30 1995-01-30
US08/380,194 1995-01-30
PCT/US1996/001212 WO1996023869A1 (fr) 1995-01-30 1996-01-30 ENZYME α-GALACTOSIDASE RECOMBINEE

Publications (1)

Publication Number Publication Date
JPH10513057A true JPH10513057A (ja) 1998-12-15

Family

ID=23500271

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8523663A Ceased JPH10513057A (ja) 1995-01-30 1996-01-30 組換えα−ガラクトシダーゼ酵素

Country Status (5)

Country Link
EP (1) EP0807165A4 (fr)
JP (1) JPH10513057A (fr)
AU (1) AU4772596A (fr)
CA (1) CA2211417A1 (fr)
WO (1) WO1996023869A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018038423A (ja) * 1999-03-11 2018-03-15 シャイア ヒューマン ジェネティック セラピーズ インコーポレイテッド α−ガラクトシダーゼＡ欠乏症の治療

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767415B2 (en) 2001-09-25 2010-08-03 Velico Medical, Inc. Compositions and methods for modifying blood cell carbohydrates
US8742079B2 (en) 2007-08-20 2014-06-03 Protalix Ltd. Saccharide-containing protein conjugates and uses thereof
US9194011B2 (en) 2009-11-17 2015-11-24 Protalix Ltd. Stabilized alpha-galactosidase and uses thereof
WO2011061736A1 (fr) * 2009-11-17 2011-05-26 Protalix Ltd. Alpha galactosidase alcaline pour le traitement de la maladie de fabry
EP2665814B1 (fr) 2011-01-20 2017-05-17 Protalix Ltd. Construction d'acide nucléique pour l'expression d'une alpha-galactosidase chez des plantes et des cellules végétales
WO2022016254A1 (fr) * 2020-07-24 2022-01-27 Hyasynth Biologicals Inc. Procédés et cellules ayant des enzymes de modification pour produire des cannabinoïdes substitués et des précurseurs
CN114752581B (zh) * 2022-04-20 2023-05-26 南京工业大学 一种α-半乳糖苷酶突变体及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1339101C (fr) * 1986-06-03 1997-07-29 Nicolaas Overbeeke Obtention d'alpha-galactosidase de guar et d'alpha-galactisidase apparente du point de vue immunitaire a l'aide d'organismes hotes transformes par des methodes a adn recombinant
DE69133066T2 (de) * 1990-01-16 2003-03-06 Centro De Ingenieria Genetica Y Biotecnologia, Cubanacan Playa Verfahren zur Expression heterologischer Gene in der Hefe Pichia Pastoris, Expressionsverfahren und transformierte Mikroorganismen
US5330901A (en) * 1991-04-26 1994-07-19 Research Corporation Technologies, Inc. Expression of human serum albumin in Pichia pastoris
AU5365094A (en) * 1992-10-22 1994-05-09 New York Blood Center, Inc., The Recycling of enzymes used to convert sub-type a, b and ab erythrocytes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018038423A (ja) * 1999-03-11 2018-03-15 シャイア ヒューマン ジェネティック セラピーズ インコーポレイテッド α−ガラクトシダーゼＡ欠乏症の治療

Also Published As

Publication number Publication date
AU4772596A (en) 1996-08-21
EP0807165A4 (fr) 1998-07-15
CA2211417A1 (fr) 1996-08-08
WO1996023869A1 (fr) 1996-08-08
EP0807165A1 (fr) 1997-11-19

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Legal Events

Date Code Title Description
A313 Final decision of rejection without a dissenting response from the applicant

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Effective date: 20040420

A02 Decision of refusal

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Effective date: 20040518