JPH11240581A - Production of double-package body - Google Patents

Abstract

PROBLEM TO BE SOLVED: To enable the high speed formation of a heat seal and the high speed filling with contents, by using, as a internal-layer resin for a two-layer film used for an insertion package body, one that is lower in fusing point than an external-layer resin, and by allowing only the internal-layer resin to be welded at the moment of heat-seal and preventing the external-layer resin from being fused. SOLUTION: In the production of a packaging container 5, the bottom of a two-layer inflation film consisting of an internal-layer resin layer 2 and an external-layer resin layer 3 is first heat-sealed to form a seal part 4. Then, contents 6 are filled into the packaging container 5 through an opening part 7, and after they are filled, the opening part 7 is heat-sealed. Thereafter, the external-layer resin layer 3 is pulled and peeled from the packaging container 5 and the entire external-layer resin layer 3 is removed, thereby completing an insertion package body 1. The internal-layer resin layer 2 used in the case is a polyethylene resin, and the external-layer resin layer 3 is one of the resins selected from a group consisting of polypropylene, poly-4-methyl-1-pentene, polyethylene terephthalate, and polyamide.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for manufacturing a package having a double structure, and more particularly to a small package in which a large content is filled with a certain content and another content is filled. The present invention relates to a method for producing a double-packed body which is inserted and integrated and is suitable for uses such as pharmaceuticals and foods.

[0002]

2. Description of the Related Art In the fields of medicines and foods, a method of preparing a plurality of raw materials by separately packaging them in advance and mixing them immediately before use is sometimes used. In particular, when the raw materials are mixed and stored, if there is a possibility that the stored materials may change over time due to the influence of light, heat, or the like, or may be contaminated by bacteria or the like at the time of mixing, such a packaging method may be used. It is valid.

One specific method is disclosed in
A package is known in which two containers containing contents described in Japanese Patent No. 4671 are connected in series, and the connecting portion is communicated when used. This method is the preferred packaging method if both containers are approximately the same size,
Sometimes one of the packaging containers must be extremely small compared to the other, and in that case, it is difficult to use because of lack of balance and difficulty in use.

[0004] As another packaging method which improves this point, there is a double package in which a small package is enclosed in a large package. In use, the contents in a small package are operated so as to flow into a large package, both contents are mixed in a large package, and then the mixture is taken out and used. If the mixture is a substance that is liable to change over time, or if it is desired to avoid contamination by bacteria or the like until immediately before use, the packaging form by this method is advantageous.

However, when manufacturing this double package,
The outer surface of the small package to be enclosed must be sterilized in advance, and the integration of both packages requires an efficient sealing technique.

For example, the heat sealing technique as a sealing method for plastics can realize a reliable seal by an extremely simple operation. However, in order to proceed with the work efficiently, it is necessary to be able to seal at a low temperature and to use a sealing jig (sealing jig). It is required from the working surface that the molten resin does not adhere to the bar). Therefore, as plastics, a two-layer plastic film composed of a low melting point resin layer serving as a heat sealing layer and a high melting point resin layer where the sealing layer does not adhere to the seal bar is often used. However, when another film is heat-sealed on the high melting point resin side of the two-layer plastic film, it is necessary to arrange a higher melting point plastic film. At that time, the already-sealed low-melting-point resin layer may be melted again at a high heat-sealing temperature and peeled off, so that sealing leakage easily occurs, which is a difficult heat-sealing molding technique.

[0007]

Therefore, in the present invention, in manufacturing a double-structured package, a small package is enclosed in a large package in order to increase the production efficiency and securely seal. Various studies were conducted for the purpose of preventing contamination of the outer surface of a small package at the time of integration and improving the heat sealing method at the time of integration, and arrived at the present invention.

[0008]

That is, the present invention provides a packaging container comprising a two-layer film, wherein the inner layer of the film is formed of a resin having a lower melting point than the outer layer resin and a poor compatibility with the outer layer resin. Then, the package is filled with the contents, and the opening is heat-sealed under the condition that only the inner layer resin is melted to form a sealed package, and then the outer layer film is peeled off, and only the inner layer film is formed. Changed to a single-layer insert package, while preparing a package made of a heat-sealable resin with the insert package and filling it with a different content to form an external package,
Inserting at least one interpolated package into the outer package;
The present invention relates to a method for manufacturing a double-packed body, characterized in that the two ends are integrated and the outer package is sealed by overlapping and heat-sealing the end of the inner package with the opening of the outer package.

[0009]

DETAILED DESCRIPTION OF THE INVENTION Method of manufacturing an interpolated package An interpolated package enclosed in a double package is manufactured through the following steps. First, a two-layer film is prepared, and a packaging container is manufactured to fill the contents. The two-layer film used here is composed of an inner resin layer disposed inside and an outer resin layer disposed outside when the packaging container is formed, and the resin forming the inner layer is lower than the outer resin. A resin having a melting point and poor compatibility with the outer layer resin is selected.

The relationship between the low melting point and the high melting point is as follows.
When the two-layer film is heat-sealed under certain temperature conditions, the inner resin melts and adheres to each other, and the outer resin does not melt at that time and therefore does not adhere to the seal bar. Say the relationship. When selecting the resin for forming the inner layer and the outer layer, the resin is first selected from the resins satisfying the above-described heat sealing relationship. Under normal heat sealing conditions, a resin having a melting point of at least 10 ° C., preferably at least 15 ° C., more preferably at least 17 ° C. lower than that of the outer layer resin is used as the inner layer resin.

Further, it is necessary that the inner layer resin and the outer layer resin have poor compatibility with each other. Here, the expression "poor in compatibility with each other" means that the inner layer and the outer layer do not completely adhere to each other during the production of the two-layer film and even under the above-mentioned heat sealing conditions. Has a relationship of being easily peeled or peeled,
It means compatibility between such resins.

[0012] The resin used for the production of the two-layer film includes various physical properties required for the insert package, such as hygiene,
It is selected from a wide range of plastics as long as it satisfies performance such as moldability, mechanical strength, transparency, and flexibility. Examples of such plastics include polyolefin resins, polyester resins, polyamide resins, acrylonitrile-based resins (for example, Barex). The type suitable for the inner layer resin and outer layer resin is selected from them,
In particular, a polyolefin resin is suitably selected for any layer because it satisfies the above-mentioned performance. In particular, a low-melting-point polyolefin resin is preferable for the inner resin layer in contact with the contents to be filled in the container.

Examples of the polyolefin resin include high-density polyethylene, low-density polyethylene, linear low-density polyethylene, branched linear low-density polyethylene,
α-olefin copolymer, ethylene-vinyl acetate copolymer, polypropylene, propylene-α-olefin copolymer, poly 4-methyl-1-pentene and the like are preferably used, and a blend of these is used. Is also good.

Examples of the ethylene-α-olefin copolymer include α-olefins such as propylene, 1-butene, 1-pentene, 1-hexene, 4-methyl-1-pentene and 1-octene.
-An ethylene copolymer containing 0.1 to 20 mol% of an olefin unit is preferable, and can be produced in a range of low density to high density using a Ziegler catalyst or a metallocene catalyst. As the propylene-α-olefin copolymer, ethylene,
A propylene copolymer containing 0.1 to 20 mol% of an α-olefin unit such as 1-butene can be produced using the above-mentioned catalyst system.

As a preferred example of the combination of the inner layer resin and the outer layer resin, when polyethylene is used as the inner layer resin, the outer layer resin may be polypropylene, poly-4-methyl-1-pentene, nylon-6 resin, nylon-66.
Resin, polyethylene terephthalate resin and the like are selected from the viewpoint of their melting points and compatibility.

Specific examples of the structure of the two-layer film include a copolymer of ethylene and 4-methyl-1-pentene, a copolymer of ethylene and 1-butene, or a copolymer of ethylene and 1-butene.
When linear low-density polyethylene, which is a copolymer with hexene, is selected as the inner layer resin and propylene homopolymer or poly-4-methyl-1-pentene is selected as the outer layer resin, heat sealing between the inner layer resins is, for example, 115 to 140. The resin is firmly adhered to each other at a temperature as low as about ° C., so that the outer layer resin does not adhere to the seal bar, and the outer layer resin layer can be easily peeled off from the packaging container when the insert package is manufactured.

Since the inner resin layer serves as a container portion of the insert package, it is required to have flexibility, impact resistance, or transparency as a container in addition to the heat sealing property.
Therefore, for example, when polyethylene is used as the inner layer resin, it is desirable that the polyethylene has a sufficient molecular weight to form a film, and has an appropriate flexibility, impact resistance, or a density or crystallinity that provides transparency. It is.
ASTM D-123 is one such polyethylene.
8 (190 ° C., 2.16 kg) has a melt flow rate of 0.1 to 50 g / 10 min, preferably 0.5
２０20 g / 10 min, and ASTM D-1505
Is selected from the range of 0.90 to 0.95 g / cm ³ , preferably 0.91 to 0.94 g / cm ³ . In order for the inner layer resin to have such physical properties, one kind of polyethylene or a blend of two or more kinds of polyethylene may be used. For example, a high-density polyethylene or a high-pressure low-density polyethylene may be mixed with a linear low-density ethylene-α-olefin copolymer to adjust the melt flow rate and the density range described above.

Further, if an easy peel property is given to an interlayer bonding portion (heat sealing portion) between the inner resin layers,
When a force is applied to the inner package during use of the double package, the contents flow out of the interlayer bonding portion and move into the outer package, so that it is suitable for mixing both contents. In such a case, as the inner layer resin, polyethylene, polypropylene, poly 1-butene, poly 4-methyl-
It is convenient to blend a predetermined amount of 1-pentene, polyamide, or the like, since easy peeling appears.

The resin constituting the outer resin layer has a molecular weight having film formability. If polypropylene is used, its melt flow rate is ASTM
0.1 to 50 g / 10 min, preferably 0.5 to 2 g, measured according to D-1238 (230 ° C., 2.16 kg).
It is desirable to be in the range of 0 g / 10 minutes. Even when using poly-4-methyl-1-pentene, the melt flow rate is 0.1 to 50 g / 10 min, preferably 0.5 to 50 g / 10 min.
It is desirable to be in the range of 30 g / 10 minutes. Others
Since the container temporarily becomes the shape of the container and is filled with the contents, the container has mechanical properties that can withstand it and a tensile strength that does not break when peeled from the inner resin layer.

The two-layer film is produced by coextrusion blown molding, coextrusion T-die molding, extrusion lamination, film compression bonding, and the like.
The thickness of the film is 20-150 μm, preferably 40
１００100 μm, the inner layer is 40-90% of the total thickness,
Preferably, it is 50-80%.

Such a two-layer film is formed into a bag, tube, bottle or other container shape by heat-sealing the bottom portion and the necessary peripheral portion, and then filling the contents and heating the opening. Seal the contents to make a package.
Alternatively, the two-layer film may be formed into a container shape such as a bag while being heat-sealed, and the contents may be filled at the same time to form a package. Furthermore, a packaging container can be manufactured at once by a blow molding method, and the contents can be filled into a sealed package.

Next, the outer layer portion is peeled off from the package,
Change to a so-called single-layer insert package consisting of an inner layer film only. When a package filled with contents is continuously manufactured from the two-layer film, the end portion of the outer layer to be peeled can be easily peeled off by continuously winding the end portion.

When the above-described two-layer film is manufactured by co-extrusion molding, two kinds of resins melted in separate extruders are directly laminated in a die without contacting with the outside air, and then the outer layer of the package is formed. The outer surface of the inner layer at the time of peeling is aseptic. Also, in the laminating process, the laminating resin is extruded onto the other film in a molten state, and the interface between the two is kept in an airtight state.

Next, a method of manufacturing the outer package will be described. The packaging container for the outer package is formed by molding a film from the above-described interpolated package and a heat-sealable resin, and the bottom and necessary peripheral portions are formed into a bag, tube, bottle, or the like by an operation such as heat sealing. Make into a container shape. The container may be directly formed by a blow molding method. Since the outer packaging container is integrated with the inner packaging body by heat sealing in a later step, it is necessary that the resins constituting both the packaging bodies are firmly adhered to each other under one sealing condition. For that purpose, it is desirable that the melting points of both resins are close to each other and that the chemical structures are similar. Therefore, both are preferably substantially similar resins, and are not necessarily limited to the same resin.

If the heat-sealing operation between the outer packaging container and the inner package is performed under mild conditions and at a low speed, the outer packaging container selects a resin that meets the above-mentioned conditions, and then directly selects the resin. Can be manufactured. However, when manufacturing operations must be performed under severe conditions such as continuing high-speed molding while preventing adhesion to the seal bar,
It is more convenient to use a laminated film having a resin conforming to the above conditions in the sealant layer.

When the inner package is manufactured from a packaging container of a polyolefin resin such as polyethylene or polypropylene, the outer package is also made of a polyolefin resin such as a homopolymer, copolymer or blend thereof of ethylene or propylene. It may be manufactured by selecting from a range or from a laminated film having such a polyolefin resin as a sealant layer.

The laminated film is a film having two or more layers in which the above-mentioned sealant layer is bonded to at least one base layer made of other polyolefin, polyester, polyamide or the like directly or via an adhesive layer.

The sealant layer forms at least an adhesive layer with the insert package, and sometimes bears part of the strength. As such a sealant resin, the polyolefin, particularly a polyethylene resin described in the section of the method for producing an insert package can be suitably used. As the physical properties of polyethylene, ASTM D-1238 (190 ° C,
2.16 kg) has a melt flow rate of 0.
1 to 50 g / 10 min, preferably 0.5 to 20 g / 10 min
And a density measured by ASTM D-1505 of 0.88 to 0.95 g / cm ³ , preferably 0.9
It is selected from the range of 0 to 0.94 g / cm ³ . This polyethylene may be a single type of polyethylene, or a blend of two or more types of polyethylene, and further a polyolefin or another polymer. For example, a linear low-density ethylene-α-olefin copolymer is mixed with a high-pressure low-density polyethylene, or a copolymer of amorphous ethylene and propylene or 1-butene is mixed. Adjustments to rates and density ranges are also possible.

Since the base layer must satisfy the performance as a container, the resin constituting the base layer has a molecular weight capable of forming a film and physical properties such as transparency, flexibility and impact resistance. A typical example of such a resin is polypropylene resin. When the adhesiveness between the sealant layer and the substrate layer is insufficient, it is desirable to provide an adhesive layer in the middle, and the copolymer is modified by graft copolymerization with a polar group-containing polyolefin such as acrylic acid, methacrylic acid, or maleic anhydride. A carboxylic acid-modified polyolefin such as polyethylene may be used for the adhesive layer.

The outer packaging container has a layer thickness of 30 to 300 μm to support the weight of the contents and withstand external impact.
m, preferably 50 to 200 μm. When the laminated film is used, the sealant layer preferably has a thickness of 10 to 90, preferably 20 to 80% of the whole. After filling the packaging container with a predetermined amount of content different from the content in the insertion package, or while molding the packaging container, the content is filled to form an external package.

Manufacturing method of double wrapping body At least one inner wrapping body prepared above is inserted into the outer wrapping body thus manufactured. that time,
An end of the inner package, for example, an opening heat seal portion of the inner package is overlapped inside the opening of the outer package, and heat sealing is performed again from the outside of the outer layer package. By this heat sealing operation, if the outer packaging container has a single-layer structure, the resin thereof is melted, and if the outer packaging container is manufactured from a laminated film, the sealant layer is melted and firmly adheres to the inner package. Then, the inner package is fixed in the outer package, the two are integrated, and the outer package is simultaneously sealed to produce a double package. The same operation can be performed even when there are a plurality of interpolated packages fixed in the outer package.

The contents to be filled into the insert and the outer package vary depending on the type of medicine, food, etc. For example, if the purpose is a high-calorie infusion bag, glucose or glucose is used.
Amino acids and other drugs are combined in predetermined amounts,
It may be filled separately. In using this double package, the contents in the insert package are moved into the external package, but the method may be arbitrary. For example, an external force may be applied to the interpolated package to break the bag. If the inner layer resin at the time of manufacturing the insert package has an easy-peeling property, similarly, a force may be applied to the insert package to move the contents from the heat-sealed portion to the outer package. it can.

Next, a manufacturing method of an embodiment of the double package according to the present invention will be described with reference to the drawings. FIG. 1 is a schematic cross-sectional view showing a state immediately before an insert package is manufactured. First, the bottom of a two-layer blown film composed of the inner resin layer 2 and the outer resin layer 3 is heat-sealed to produce a packaging container 5 having a seal part 4. Next, the contents (A) 6 are filled in the packaging container 5, and the remaining opening 7 is heat-sealed to form a package. Thereafter, as shown in FIG. 1, the outer resin layer 3 is peeled off from the packaging container 5, and when all of the outer resin layers are removed, the insert package 1 is manufactured.

FIG. 2 is a schematic sectional view of the double package. The bottom portion 10 of the two-layer blown film composed of the sealant layer 8 and the base material layer 9 is heat-sealed to form an external packaging container. This container is filled with the contents (B) 11 to produce the external package 12. Next, the insert package 1 is inserted into the external package 12, and at this time, the outer surface of the opening heat seal portion 7 of the insert package 1 is overlapped on the inner inner surface of the opening 13 of the external package, and Heat sealing is performed from the outside of the package opening 13. As a result, the opening heat seal portion 7 of the inner package and the opening 13 of the outer package are adhered, and the inner package 1 is attached to the opening 13 of the outer package 12.
And they are integrated. At the same time, the outer package 12 is sealed, and the double package 14 is completed.

[0035]

According to the present invention, in the two-layer film used for manufacturing the insert package, since the inner layer resin has a lower melting point than the outer layer resin, only the inner layer resin is melted during heat sealing. The outer layer resin does not melt and thus does not adhere to the heat seal bar. Therefore, heat seal molding at a high speed and high-speed filling of contents can be performed.

Also, the two-layer film is manufactured in a sterile state between the layers, and then the inner package is obtained by a simple operation of peeling the outer layer from the packaging container manufactured from the two-layer film. Even if a sterilization operation is not performed, the outer surface of the insert package can be made aseptic as it is.

Furthermore, since the outer package is manufactured by itself or the sealant layer is made of a resin which can be heat-sealed with the inner package, the heat seal of both can be easily and reliably sealed at a low temperature. The contents in the double package can be kept sterile.

[0038]

Next, the present invention will be described with reference to examples.
The present invention is not limited to this embodiment. Example 1 30 μm thick polyethylene inner layer (ethylene / 4-methyl-1-pentene copolymer, melt flow rate 2.0 g / 10 min, density 0.920 g / cm ³ ,
(Melting point 115 ° C. measured by DSC) and a 30 μm thick poly-4-methyl-1-pentene outer layer (melt flow rate 26.0 g / 10 min, density 0.834 g / cm ³ , melting point 240 ° C.) The blown film was produced by a coextrusion molding method, and the bottom was heat-sealed at 120 ° C. to form a bag. The bag was filled with an amino acid and the mouth was heat-sealed in the same manner. Thereafter, the poly-4 methyl-1-pentene layer as the outer layer was peeled off to obtain a package having only the polyethylene layer.

On the other hand, the inner layer was made of 50 μm polyethylene (sealant layer: ethylene / 1-hexene copolymer, melt flow rate 4.0 g / 10 min, density 0.920 g / cm
³ , melting point 116 ° C.), the intermediate layer is 10 μm maleic anhydride graft-modified polyethylene (adhesive layer), the outer layer is 30 μm
Propylene homopolymer (base layer: melt flow rate 4.0 g / 10 min, density 0.910 g / cm ³ , melting point 1
A three-layer co-extruded blown film having a thickness of 90 μm and a thickness of 61 ° C.) was used, and the bottom was heat-sealed to form a large bag. It was filled with glucose. A small bag filled with amino acid was put into the bag, the mouth portions of both were overlapped, and heat sealing was performed at 130 ° C. from the outside. The small bag was secured at the mouth of the large bag, and the large bag was also sealed.

[Brief description of the drawings]

FIG. 1 is a schematic sectional view showing a state immediately before an embodiment of an insertion package according to the present invention is manufactured.

FIG. 2 is a schematic cross-sectional view of one embodiment of a double package according to the present invention.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 ... Inner package 2 ... Inner resin layer 3 ... Outer resin layer 6 ... Content (A) 8 ... Sealant layer 9 ... Base layer 11 ... Content (B) 14 ・ ・ ・ Double package

Claims (4)

[Claims] 1. A packaging container comprising a two-layer film is prepared, and the inner layer of the film is formed of a resin having a lower melting point than the outer layer resin and a poor compatibility with the outer layer resin. Into a sealed package by heat-sealing the opening under the condition that only the inner layer resin is filled and then the outer layer film is peeled off to form a single-layer insert package consisting only of the inner layer film On the other hand, a packaging container made of a resin that can be heat-sealed with the above-mentioned insertion packaging body is prepared and filled with another content to form an outer packaging body, and then at least one of the outer packaging bodies is contained in the outer packaging body. A double wrapping, wherein the inner wrapping is inserted into the inner wrapping, and the outer wrapping is sealed by heat sealing the end portion of the inner wrapping over the opening of the outer wrapping, thereby integrating the two and sealing the outer wrapping. How to make the body. 2. The two-layer film according to claim 1, wherein the inner layer is formed of a polyethylene resin, and the outer layer is formed of one resin selected from polypropylene, poly-4-methyl-1-pentene, polyethylene terephthalate, and polyamide. Item 2. The method for producing a double package according to Item 1. 3. The method according to claim 1, wherein the two-layer film is formed by a co-extrusion method. 4. The packaging container for the external package, wherein the sealant layer is made of a resin that can be heat-sealed with the internal package,
The method for producing a double package according to claim 1, wherein the package is formed from a laminated film including a base film and a base material layer.