JPH11500741A5 - - Google Patents

Info

Publication number
JPH11500741A5
JPH11500741A5 JP1997511044A JP51104497A JPH11500741A5 JP H11500741 A5 JPH11500741 A5 JP H11500741A5 JP 1997511044 A JP1997511044 A JP 1997511044A JP 51104497 A JP51104497 A JP 51104497A JP H11500741 A5 JPH11500741 A5 JP H11500741A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1997511044A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11500741A (ja
Filing date
Publication date
Priority claimed from IL11509695A external-priority patent/IL115096A/xx
Priority claimed from US08/569,042 external-priority patent/US6117974A/en
Application filed filed Critical
Publication of JPH11500741A publication Critical patent/JPH11500741A/ja
Publication of JPH11500741A5 publication Critical patent/JPH11500741A5/ja
Ceased legal-status Critical Current

Links

JP9511044A 1995-08-29 1996-08-28 バックボーン環化ペプチド類似体のライブラリー Ceased JPH11500741A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IL11509695A IL115096A (en) 1995-08-29 1995-08-29 Libraries of backbone cyclized peptidomimetics
US08/569,042 1995-12-07
US08/569,042 US6117974A (en) 1991-10-02 1995-12-07 Libraries of backbone-cyclized peptidomimetics
US115096 1995-12-07
PCT/IL1996/000091 WO1997009344A2 (en) 1995-08-29 1996-08-28 Librairies of backbone-cyclized peptidomimetics

Publications (2)

Publication Number Publication Date
JPH11500741A JPH11500741A (ja) 1999-01-19
JPH11500741A5 true JPH11500741A5 (2) 2004-08-12

Family

ID=26323124

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9511044A Ceased JPH11500741A (ja) 1995-08-29 1996-08-28 バックボーン環化ペプチド類似体のライブラリー

Country Status (6)

Country Link
US (2) US6117974A (2)
EP (1) EP0923601A2 (2)
JP (1) JPH11500741A (2)
AU (1) AU714917B2 (2)
CA (1) CA2230861A1 (2)
WO (1) WO1997009344A2 (2)

Families Citing this family (35)

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US6117974A (en) * 1991-10-02 2000-09-12 Peptor Limited Libraries of backbone-cyclized peptidomimetics
US6407059B1 (en) * 1994-06-08 2002-06-18 Peptor Limited Conformationally constrained backbone cyclized peptide analogs
US5770687A (en) * 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
US6841533B1 (en) 1995-12-07 2005-01-11 Peptor Limited Conformationally constrained backbone cyclized interleukin-6 antagonists
US6355613B1 (en) * 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
IL122343A0 (en) * 1997-11-27 1998-04-05 Yissum Res Dev Co Inhibition of nuclear import by backbone cyclic peptide analogs
WO1999028339A1 (en) * 1997-12-02 1999-06-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Backbone cyclic peptide fragments and their analogs derived from pban 1-33, useful as insecticides
IL136617A0 (en) * 1997-12-15 2001-06-14 Peptor Ltd Branched building units for synthesizing cyclic peptides
US6355616B1 (en) 1999-06-25 2002-03-12 Xoma (Us) Technology Ltd. Derivative compounds derived from or based on bactericidal/permeability-increasing protein
AU2001288847A1 (en) * 2000-09-07 2002-03-22 Biosyntema Inc. Conformationally constrained labeled peptides for imaging and therapy
US20030144260A1 (en) * 2002-01-03 2003-07-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Heterocyclic compounds, method of developing new drug leads and combinatorial libraries used in such method
EP1468013A4 (en) * 2002-01-03 2005-03-16 Yissum Res Dev Co CYCLIC PEPTIDES WITH CARBON SKELETON HAVING RESTRICTED CONFORMATION
IL148921A0 (en) 2002-03-26 2002-09-12 Peptor Ltd Photo active backbone cyclized somatostatin analogs for optical imaging and photodynamic therapy
FR2838444B1 (fr) * 2002-04-10 2016-01-01 Neovacs Nouveaux peptides et leur application en therapeutique
US6994770B2 (en) * 2002-12-20 2006-02-07 Kimberly-Clark Worldwide, Inc. Strength additives for tissue products
US7147751B2 (en) * 2002-12-20 2006-12-12 Kimberly-Clark Worldwide, Inc. Wiping products having a low coefficient of friction in the wet state and process for producing same
EP1580559B1 (en) * 2004-03-23 2013-12-25 Bio-Rad Laboratories, Inc. Methods for reducing the variance between analyte concentrations taken from complex sample mixtures
US20060068661A1 (en) * 2004-09-29 2006-03-30 Kimberly-Clark Worldwide, Inc. Wiping products having a high equilibrium moisture and a low coefficient of friction
US20060211507A1 (en) * 2005-03-21 2006-09-21 Intertex, Inc. Stake for securing inflatable devices
CN101203527A (zh) * 2005-05-31 2008-06-18 耶路撒冷希伯来大学伊森姆研究发展公司 主链环化的促黑皮质素激素（αMSH）类似物
US20080015145A1 (en) 2006-07-11 2008-01-17 Maria Gyongyossy-Issa Mimotope receptors and inhibitors for platelet-platelet and platelet-endothelium interactions
US20100104572A1 (en) * 2006-11-02 2010-04-29 Sylvie Luria Methods for screening for therapeutic molecules and use of the molecules therefrom
EP2417150A2 (en) * 2009-04-06 2012-02-15 Matrix Laboratories Ltd An improved process for the preparation of desmopressin or its pharmaceutically acceptable salts
US20120270774A1 (en) 2009-08-28 2012-10-25 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Macrocyclic compounds, compositions comprising them and methods for preventing or treating hiv infection
FR2956115B1 (fr) 2010-02-05 2012-04-06 Isp Investments Inc Nouveaux peptides activateurs de la caspase-14 et compositions les comprenant
WO2013026015A1 (en) 2011-08-18 2013-02-21 Dana-Farber Cancer Institute, Inc. Muc1 ligand traps for use in treating cancers
EP2807182A1 (en) 2012-01-23 2014-12-03 Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. Stabilized peptide helices for inhibiting dimerization of chemokine c motif receptor 2 (ccr2)
US9725484B2 (en) 2013-02-25 2017-08-08 The Regents Of The University Of Michigan Methods and compositions for the treatment of bone remodeling disorders
WO2015087334A1 (en) 2013-12-15 2015-06-18 Yissum Research Develoment Company Of The Hebrew University Of Jerusalem Ltd. Viperistatin-derived peptides and uses thereof
EP3134106A1 (en) * 2014-02-24 2017-03-01 The Arizona Board Of Regents On Behalf Of The University Of Arizona Multivalent/multifunctional ligands with agonist activities at opioid receptors and antagonist activities at nk1 receptor for relief of pain
CN109415413A (zh) 2016-06-07 2019-03-01 耶路撒冷希伯来大学伊森姆研究发展有限公司 髓样分化因子88(myd88)的主链环化抑制肽
US11261215B2 (en) 2017-09-19 2022-03-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Somatostatin prodrugs
US20220119474A1 (en) 2019-02-21 2022-04-21 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Par4 derived peptides, analogs and uses thereof
WO2022003673A1 (en) 2020-06-30 2022-01-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Humanin analogs and uses thereof
WO2025141573A1 (en) 2023-12-27 2025-07-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Calreticulin peptidomimetic inhibitors and prodrugs

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US3988304A (en) * 1975-08-25 1976-10-26 American Home Products Corporation Cyclic dodecapeptide derivatives of somatostatin and intermediates thereof
US4054558A (en) * 1976-05-24 1977-10-18 American Home Products Corporation Cyclic dodecapeptide and intermediates therefor
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US4310518A (en) * 1979-10-31 1982-01-12 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
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US5807979A (en) * 1988-04-08 1998-09-15 The Scripps Research Institute Synthetic, three-dimensionally stabilized polypeptide mimics of HIV
AU3534989A (en) * 1988-04-08 1989-11-03 Scripps Clinic And Research Foundation Polypeptides stabilized by covalent hydrogen bond replacements
US5010175A (en) * 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
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US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
WO1992013878A2 (en) * 1991-02-07 1992-08-20 Board Of Trustees Of The University Of Illinois Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
US5475085A (en) * 1991-02-07 1995-12-12 Molecumetics, Ltd. Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
DE4119544C1 (2) * 1991-06-13 1992-10-15 Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf), 3300 Braunschweig, De
US5286846A (en) * 1991-06-14 1994-02-15 The Government Of The United States Of America As Represented By The Dept. Of Health And Human Services Amino acid derivative and bromoacetyl modified peptides for the preparation of synthetic peptide polymers, conjugated peptides, and cyclic peptides
US5364851A (en) * 1991-06-14 1994-11-15 International Synthecon, Llc Conformationally restricted biologically active peptides, methods for their production and uses thereof
US6117974A (en) * 1991-10-02 2000-09-12 Peptor Limited Libraries of backbone-cyclized peptidomimetics
IL99628A (en) * 1991-10-02 2004-07-25 Yissum Res Dev Co Processes for the preparation of cyclic peptides, and pharmaceutical compositions containing them
DE69319733T2 (de) * 1992-06-04 1999-01-14 Merrell Dow Pharmaceuticals Inc., Cincinnati, Ohio In der konformation beschränkte peptid analoge als wirkstoff gegen plättchenaggregation
US5371070A (en) * 1992-11-09 1994-12-06 The Salk Institute For Biological Studies Bicyclic GnRH antagonists and a method for regulating the secretion of gonadotropins
EP0788370A4 (en) * 1993-07-09 1998-07-08 Smithkline Beecham Corp CYCLIC, PARTIAL RANDOM PEPTIDE LIBRARIES
DE69526216T2 (de) * 1994-01-14 2002-11-14 Xoma Technology Ltd., Berkeley Antifungaleverfahren und mitteln
IL109943A (en) * 1994-06-08 2006-08-01 Develogen Israel Ltd Conformationally constrained backbone cyclized peptide analogs
US6051554A (en) * 1995-06-07 2000-04-18 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
US5770687A (en) * 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
CN101385190A (zh) * 2003-12-24 2009-03-11 莫莱克斯公司 多通道波导结构

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