JPH11510142A5 - - Google Patents
Info
- Publication number
- JPH11510142A5 JPH11510142A5 JP1997506909A JP50690997A JPH11510142A5 JP H11510142 A5 JPH11510142 A5 JP H11510142A5 JP 1997506909 A JP1997506909 A JP 1997506909A JP 50690997 A JP50690997 A JP 50690997A JP H11510142 A5 JPH11510142 A5 JP H11510142A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US136595P | 1995-07-21 | 1995-07-21 | |
| US08/675,454 US6248720B1 (en) | 1996-07-03 | 1996-07-03 | Method for gene therapy using nucleic acid loaded polymeric microparticles |
| US60/001,365 | 1996-07-03 | ||
| US08/675,454 | 1996-07-03 | ||
| PCT/US1996/011990 WO1997003702A1 (en) | 1995-07-21 | 1996-07-19 | A method for gene therapy using nucleic acid loaded polymeric microparticles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11510142A JPH11510142A (ja) | 1999-09-07 |
| JPH11510142A5 true JPH11510142A5 (2) | 2004-08-26 |
Family
ID=26668935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9506909A Ceased JPH11510142A (ja) | 1995-07-21 | 1996-07-19 | 核酸負荷ポリマー微粒子を使用した遺伝子治療法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6677313B1 (2) |
| EP (1) | EP0840623B1 (2) |
| JP (1) | JPH11510142A (2) |
| AU (1) | AU714584B2 (2) |
| CA (1) | CA2227287A1 (2) |
| WO (1) | WO1997003702A1 (2) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US20030026782A1 (en) | 1995-02-07 | 2003-02-06 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
| US6143211A (en) * | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
| EP0840623B1 (en) | 1995-07-21 | 2007-07-18 | Brown University Research Foundation | Compositions for gene therapy comprising nucleic acid loaded polymeric microparticles |
| DE69608122T3 (de) * | 1995-11-09 | 2011-06-16 | Microbiological Research Authority Camr, Salisbury | Mikroverkapselte dna zur impfung und gentherapie |
| GB9607035D0 (en) * | 1996-04-03 | 1996-06-05 | Andaris Ltd | Spray-dried microparticles as therapeutic vehicles |
| EP1005374B1 (en) * | 1997-01-22 | 2007-04-18 | Zycos Inc. | Microparticles for delivery of nucleic acid |
| US20020182258A1 (en) * | 1997-01-22 | 2002-12-05 | Zycos Inc., A Delaware Corporation | Microparticles for delivery of nucleic acid |
| US6197229B1 (en) * | 1997-12-12 | 2001-03-06 | Massachusetts Institute Of Technology | Method for high supercoiled DNA content microspheres |
| US6254890B1 (en) | 1997-12-12 | 2001-07-03 | Massachusetts Institute Of Technology | Sub-100nm biodegradable polymer spheres capable of transporting and releasing nucleic acids |
| PT1077722E (pt) | 1998-05-22 | 2006-12-29 | Coley Pharm Group Inc | Produtos e composições para utilização na indução da imunidade mucosal |
| CA2397404C (en) * | 2000-01-14 | 2008-12-02 | Brown University Research Foundation | Micronized freeze-dried particles |
| US7029700B2 (en) | 2000-01-14 | 2006-04-18 | Brown University Research Foundation | Micronized freeze-dried particles |
| JP4751556B2 (ja) | 2000-02-28 | 2011-08-17 | ジーンシーグス， インコーポレイテッド | ナノカプセルカプセル化システムおよび方法 |
| US7256180B2 (en) * | 2000-04-28 | 2007-08-14 | Supratek Pharma Inc. | Compositions and methods for inducing activation of dendritic cells |
| US20040142475A1 (en) * | 2000-06-02 | 2004-07-22 | Barman Shikha P. | Delivery systems for bioactive agents |
| AUPR011700A0 (en) * | 2000-09-14 | 2000-10-05 | Austin Research Institute, The | Composition comprising immunogenic virus sized particles (VSP) |
| DE60130253D1 (de) | 2000-11-21 | 2007-10-11 | Michael P Diamond | Zusammensetzungen zur verhinderung der adhäsion |
| EP1423175B1 (en) * | 2001-08-08 | 2013-10-02 | Brown University Research Foundation | Methods for micronization of hydrophobic drugs |
| CA2469718A1 (en) * | 2001-12-10 | 2003-06-19 | Spherics, Inc. | Methods and products useful in the formation and isolation of microparticles |
| US8153141B2 (en) | 2002-04-04 | 2012-04-10 | Coley Pharmaceutical Gmbh | Immunostimulatory G, U-containing oligoribonucleotides |
| CA2492807A1 (en) * | 2002-07-29 | 2004-03-04 | Nanodel Technologies Gmbh | Nanoparticles for dna administration to a target organ |
| EP1569620A4 (en) * | 2002-10-30 | 2006-03-22 | Spherics Inc | NANOPARTICULAR BIOACTIVE AGENTS |
| US7217428B2 (en) * | 2004-05-28 | 2007-05-15 | Technology Innovations Llc | Drug delivery apparatus utilizing cantilever |
| US7935517B2 (en) * | 2004-09-22 | 2011-05-03 | Nanolab, Inc. | Nanospearing for molecular transportation into cells |
| US20090311767A1 (en) * | 2005-04-21 | 2009-12-17 | Chiles Thomas C | Method for molecular delivery into cells using naonotube spearing |
| PL1957647T3 (pl) | 2005-11-25 | 2015-07-31 | Zoetis Belgium S A | Oligorybonukleotydy immunostymulujące |
| WO2008137066A1 (en) * | 2007-05-02 | 2008-11-13 | The Board Of Regents Of The University Of Oklahoma | Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases |
| EP2170353B1 (en) | 2007-05-18 | 2015-06-03 | AdiuTide Pharmaceuticals GmbH | Phosphate-modified oligonucleotide analogs with immunostimulatory activity |
| US8303573B2 (en) | 2007-10-17 | 2012-11-06 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| US8789536B2 (en) | 2007-10-17 | 2014-07-29 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| US20090105561A1 (en) * | 2007-10-17 | 2009-04-23 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Medical or veterinary digestive tract utilization systems and methods |
| US8707964B2 (en) * | 2007-10-31 | 2014-04-29 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| US8808276B2 (en) * | 2007-10-23 | 2014-08-19 | The Invention Science Fund I, Llc | Adaptive dispensation in a digestive tract |
| US20090163894A1 (en) * | 2007-10-31 | 2009-06-25 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Medical or veterinary digestive tract utilization systems and methods |
| US8808271B2 (en) * | 2007-10-31 | 2014-08-19 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| US8333754B2 (en) * | 2007-10-31 | 2012-12-18 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| US8109920B2 (en) * | 2007-10-31 | 2012-02-07 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| US20090137866A1 (en) * | 2007-11-28 | 2009-05-28 | Searete Llc, A Limited Liability Corporation Of The State Delaware | Medical or veterinary digestive tract utilization systems and methods |
| EP3978928A1 (en) | 2008-11-14 | 2022-04-06 | The Brigham and Women's Hospital, Inc. | Therapeutic and diagnostic methods relating to cancer stem cells |
| CA2959660A1 (en) | 2014-09-03 | 2016-03-10 | Genesegues, Inc. | Therapeutic nanoparticles and related compositions, methods, and systems |
| US12433876B2 (en) | 2019-08-30 | 2025-10-07 | University Of Rochester | Septin inhibitors for treatment of cancers |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3639306A (en) | 1968-08-08 | 1972-02-01 | Amicon Corp | Encapsulating particles and process for making same |
| US3615024A (en) | 1968-08-26 | 1971-10-26 | Amicon Corp | High flow membrane |
| JPS528795B2 (2) | 1971-12-30 | 1977-03-11 | ||
| US4637905A (en) | 1982-03-04 | 1987-01-20 | Batelle Development Corporation | Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or ε-caprolactones |
| US4818542A (en) * | 1983-11-14 | 1989-04-04 | The University Of Kentucky Research Foundation | Porous microspheres for drug delivery and methods for making same |
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| EP0248531A3 (en) * | 1986-05-02 | 1988-09-28 | Southern Research Institute | Encapsulated nucleic acids |
| EP0257915B1 (en) | 1986-08-11 | 1993-03-10 | Innovata Biomed Limited | Pharmaceutical formulations comprising microcapsules |
| US5075109A (en) * | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| FR2608942B1 (fr) | 1986-12-31 | 1991-01-11 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules |
| US4861627A (en) | 1987-05-01 | 1989-08-29 | Massachusetts Institute Of Technology | Preparation of multiwall polymeric microcapsules |
| WO1990013361A1 (en) | 1989-05-04 | 1990-11-15 | Southern Research Institute | Improved encapsulation process and products therefrom |
| US4997904A (en) | 1989-08-25 | 1991-03-05 | Nova Pharmaceutical Corporation | Aromatic polyanhydride compositions |
| AU640232B2 (en) | 1990-04-27 | 1993-08-19 | Allergan, Inc. | Polymeric drug delivery system |
| US5460831A (en) | 1990-06-22 | 1995-10-24 | The Regents Of The University Of California | Targeted transfection nanoparticles |
| US5518731A (en) | 1990-09-27 | 1996-05-21 | Allergan, Inc. | Nonaqueous fluorinated drug delivery vehicle suspensions |
| US5516670A (en) | 1991-09-30 | 1996-05-14 | Kuehnle; Adelheid R. | Magnetophoretic particle delivery method and apparatus for the treatment of cells |
| US5531925A (en) | 1991-10-04 | 1996-07-02 | Gs Biochem Ab | Particles, method of preparing said particles and uses thereof |
| US5288502A (en) | 1991-10-16 | 1994-02-22 | The University Of Texas System | Preparation and uses of multi-phase microspheres |
| US6197346B1 (en) | 1992-04-24 | 2001-03-06 | Brown Universtiy Research Foundation | Bioadhesive microspheres and their use as drug delivery and imaging systems |
| US5478745A (en) | 1992-12-04 | 1995-12-26 | University Of Pittsburgh | Recombinant viral vector system |
| BR9405798A (pt) | 1993-02-22 | 1995-12-12 | Vivorx Pharmaceuticals Inc | Métodos para liberação in vivo de material biológico e composições úteis dos mesmos |
| NZ265555A (en) | 1993-04-19 | 1997-09-22 | Medisorb Technologies Internat | Biodegradable microparticle compositions of antisense oligodeoxyribonucleotides |
| JPH08510639A (ja) * | 1993-04-19 | 1996-11-12 | メディソーブ・テクノロジーズ・インターナショナル・リミテッド・パートナーシップ | 細胞取込みと遺伝子発現の促進と標的化をもたらす接合体と核酸のカプセル化 |
| AU7102194A (en) | 1993-06-30 | 1995-01-24 | Dcv Biologics L.P. | A method for introducing a biological substance into a target |
| EP0804249A2 (en) * | 1994-03-15 | 1997-11-05 | Brown University Research Foundation | Polymeric gene delivery system |
| US5480914A (en) | 1994-05-06 | 1996-01-02 | Allergan, Inc. | Nonaqueous thixotropic drug delivery suspensions and methods of their use |
| GB9412273D0 (en) | 1994-06-18 | 1994-08-10 | Univ Nottingham | Administration means |
| US6248720B1 (en) | 1996-07-03 | 2001-06-19 | Brown University Research Foundation | Method for gene therapy using nucleic acid loaded polymeric microparticles |
| EP0840623B1 (en) | 1995-07-21 | 2007-07-18 | Brown University Research Foundation | Compositions for gene therapy comprising nucleic acid loaded polymeric microparticles |
| US6143211A (en) | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
| DE69608122T3 (de) * | 1995-11-09 | 2011-06-16 | Microbiological Research Authority Camr, Salisbury | Mikroverkapselte dna zur impfung und gentherapie |
| US5783567A (en) | 1997-01-22 | 1998-07-21 | Pangaea Pharmaceuticals, Inc. | Microparticles for delivery of nucleic acid |
-
1996
- 1996-07-19 EP EP96928007A patent/EP0840623B1/en not_active Expired - Lifetime
- 1996-07-19 WO PCT/US1996/011990 patent/WO1997003702A1/en not_active Ceased
- 1996-07-19 CA CA002227287A patent/CA2227287A1/en not_active Abandoned
- 1996-07-19 AU AU67623/96A patent/AU714584B2/en not_active Ceased
- 1996-07-19 JP JP9506909A patent/JPH11510142A/ja not_active Ceased
-
2000
- 2000-10-03 US US09/678,764 patent/US6677313B1/en not_active Expired - Fee Related