JPH11510373A - インフルエンザ菌由来のｏｍｐ２６抗原 - Google Patents

インフルエンザ菌由来のｏｍｐ２６抗原

Info

Publication number
JPH11510373A
JPH11510373A JP9504247A JP50424797A JPH11510373A JP H11510373 A JPH11510373 A JP H11510373A JP 9504247 A JP9504247 A JP 9504247A JP 50424797 A JP50424797 A JP 50424797A JP H11510373 A JPH11510373 A JP H11510373A
Authority
JP
Japan
Prior art keywords
protein
omp26
amino acid
haemophilus influenzae
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9504247A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11510373A5 (2
Inventor
キド，ジェネル
クリップス，アラン
スミス，クリストファー，ジョン
Original Assignee
コーテックス インターナショナル リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by コーテックス インターナショナル リミテッド filed Critical コーテックス インターナショナル リミテッド
Publication of JPH11510373A publication Critical patent/JPH11510373A/ja
Publication of JPH11510373A5 publication Critical patent/JPH11510373A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
JP9504247A 1995-06-27 1996-06-27 インフルエンザ菌由来のｏｍｐ２６抗原 Pending JPH11510373A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9513074.6 1995-06-27
GBGB9513074.6A GB9513074D0 (en) 1995-06-27 1995-06-27 Novel anigen
PCT/GB1996/001549 WO1997001638A1 (en) 1995-06-27 1996-06-27 Omp26 antigen from haemophilus influenzae

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008226372A Division JP2009034107A (ja) 1995-06-27 2008-09-03 インフルエンザ菌由来のｏｍｐ２６抗原

Publications (2)

Publication Number Publication Date
JPH11510373A true JPH11510373A (ja) 1999-09-14
JPH11510373A5 JPH11510373A5 (2) 2004-10-14

Family

ID=10776746

Family Applications (2)

Application Number Title Priority Date Filing Date
JP9504247A Pending JPH11510373A (ja) 1995-06-27 1996-06-27 インフルエンザ菌由来のｏｍｐ２６抗原
JP2008226372A Pending JP2009034107A (ja) 1995-06-27 2008-09-03 インフルエンザ菌由来のｏｍｐ２６抗原

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008226372A Pending JP2009034107A (ja) 1995-06-27 2008-09-03 インフルエンザ菌由来のｏｍｐ２６抗原

Country Status (18)

Country Link
US (4) US6245338B1 (2)
EP (1) EP0835313B1 (2)
JP (2) JPH11510373A (2)
KR (1) KR19990028423A (2)
CN (1) CN1144875C (2)
AT (1) ATE317013T1 (2)
AU (1) AU708061B2 (2)
CA (1) CA2225405A1 (2)
DE (1) DE69635783T2 (2)
ES (1) ES2259443T3 (2)
GB (1) GB9513074D0 (2)
MX (1) MX9710412A (2)
NO (1) NO976119L (2)
NZ (1) NZ311120A (2)
RU (1) RU2221045C2 (2)
TW (1) TW457247B (2)
WO (1) WO1997001638A1 (2)
ZA (1) ZA965482B (2)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009149642A (ja) * 2000-10-02 2009-07-09 Id Biomedical Corp ヘモフィルス・インフルエンゼ抗原及び対応ｄｎａ断片
JP2017529092A (ja) * 2014-09-24 2017-10-05 陳輝 バイオ製品における細菌エンドトキシンを除去する試薬キット、方法及びそのバイオ製品の製造方法

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6468765B1 (en) 1995-04-21 2002-10-22 Human Genome Sciences, Inc. Selected Haemophilus influenzae Rd polynucleotides and polypeptides
US6355450B1 (en) 1995-04-21 2002-03-12 Human Genome Sciences, Inc. Computer readable genomic sequence of Haemophilus influenzae Rd, fragments thereof, and uses thereof
GB9904183D0 (en) * 1999-02-24 1999-04-14 Smithkline Beecham Biolog Novel compounds
ES2275499T3 (es) 1999-03-19 2007-06-16 Glaxosmithkline Biologicals S.A. Vacuna contra streptococcus pneumoniae.
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
RU2185191C1 (ru) * 2001-02-01 2002-07-20 Ростовский научно-исследовательский институт микробиологии и паразитологии Способ получения антигенного препарата haemophilus influenzae типа b (hib)
GB0103171D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
EP1524991A1 (en) 2002-08-02 2005-04-27 GlaxoSmithKline Biologicals S.A. Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria
CN101687025A (zh) * 2005-03-30 2010-03-31 诺华疫苗和诊断公司 B型流感嗜血杆菌
CN100357318C (zh) * 2005-10-11 2007-12-26 中山大学 美人鱼发光杆菌外膜蛋白w和编码序列及其制备方法和应用
KR100743604B1 (ko) * 2005-12-05 2007-07-27 볼보 컨스트럭션 이키프먼트 홀딩 스웨덴 에이비 차량용 머플러 구조
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
PL1973564T3 (pl) 2005-12-22 2017-04-28 Glaxosmithkline Biologicals S.A. Szczepionki zawierające koniugaty polisacharydu otoczkowego streptococcus pneumoniae
AU2007206114B2 (en) 2006-01-17 2013-01-24 Arne Forsgren A novel surface exposed Haemophilus influenzae protein (protein E; pE)
SI2167121T1 (sl) 2007-06-26 2015-12-31 Glaxosmithkline Biologicals S.A. Cepivo, ki obsega kapsularne polisaharidne konjugate Streptococcusa pneumoniae
GB201003922D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Conjugation process
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
EP2544714A1 (en) 2010-03-10 2013-01-16 GlaxoSmithKline Biologicals S.A. Vaccine composition
GB201103836D0 (en) 2011-03-07 2011-04-20 Glaxosmithkline Biolog Sa Conjugation process
US20130156803A1 (en) 2011-06-04 2013-06-20 Rochester General Hospital Research Institute Compositions and methods related to p6
CN104321078A (zh) * 2012-04-26 2015-01-28 诺华股份有限公司 抗原和抗原组合
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
GB201621686D0 (en) 2016-12-20 2017-02-01 Glaxosmithkline Biologicals Sa Novel methods for inducing an immune response
CA3063954A1 (en) 2017-05-30 2018-12-06 Glaxosmithline Biologicals S.A. Methods for manufacturing an adjuvant
BR112020010790A2 (pt) 2017-12-01 2020-11-10 Glaxosmithkline Biologicals S.A. purificação da saponina
US20210283238A1 (en) 2018-08-07 2021-09-16 Glaxosmithkline Biologicals Sa Novel processes and vaccines
WO2020109365A1 (en) 2018-11-29 2020-06-04 Glaxosmithkline Biologicals Sa Methods for manufacturing an adjuvant
JP7640473B2 (ja) 2019-06-05 2025-03-05 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム サポニン精製
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins
GB202205833D0 (en) 2022-04-21 2022-06-08 Glaxosmithkline Biologicals Sa Bacteriophage
WO2024017827A1 (en) 2022-07-19 2024-01-25 Glaxosmithkline Biologicals Sa Continuous process for vaccine production

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69033600T2 (de) * 1989-03-09 2001-04-05 American Cyanamid Co., Madison Verfahren zur Isolierung von Haemopnilus influenzae Protein-E
GB8924473D0 (en) * 1989-10-31 1989-12-20 Connaught Lab Outer membrane protein p1 and peptides of haemophilus influenzae b
GB9224584D0 (en) * 1992-11-23 1993-01-13 Connaught Lab Use of outer membrane protein d15 and its peptides as vaccine against haempohilus influenzae diseases

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009149642A (ja) * 2000-10-02 2009-07-09 Id Biomedical Corp ヘモフィルス・インフルエンゼ抗原及び対応ｄｎａ断片
JP2011231114A (ja) * 2000-10-02 2011-11-17 Id Biomedical Corp ヘモフィルス・インフルエンゼ抗原及び対応ｄｎａ断片
JP2017529092A (ja) * 2014-09-24 2017-10-05 陳輝 バイオ製品における細菌エンドトキシンを除去する試薬キット、方法及びそのバイオ製品の製造方法

Also Published As

Publication number Publication date
AU6236396A (en) 1997-01-30
RU2221045C2 (ru) 2004-01-10
TW457247B (en) 2001-10-01
DE69635783T2 (de) 2006-11-02
WO1997001638A1 (en) 1997-01-16
KR19990028423A (ko) 1999-04-15
US6284477B1 (en) 2001-09-04
AU708061B2 (en) 1999-07-29
CN1144875C (zh) 2004-04-07
JP2009034107A (ja) 2009-02-19
NO976119D0 (no) 1997-12-29
EP0835313A1 (en) 1998-04-15
US6313281B1 (en) 2001-11-06
US6254875B1 (en) 2001-07-03
EP0835313B1 (en) 2006-02-01
ES2259443T3 (es) 2006-10-01
DE69635783D1 (de) 2006-04-13
CN1189186A (zh) 1998-07-29
MX9710412A (es) 1998-07-31
GB9513074D0 (en) 1995-08-30
NO976119L (no) 1998-02-26
NZ311120A (en) 1999-10-28
ATE317013T1 (de) 2006-02-15
CA2225405A1 (en) 1997-01-16
US6245338B1 (en) 2001-06-12
ZA965482B (en) 1997-12-29

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