JPH11510488A5 - - Google Patents

Info

Publication number
JPH11510488A5
JPH11510488A5 JP1997506919A JP50691997A JPH11510488A5 JP H11510488 A5 JPH11510488 A5 JP H11510488A5 JP 1997506919 A JP1997506919 A JP 1997506919A JP 50691997 A JP50691997 A JP 50691997A JP H11510488 A5 JPH11510488 A5 JP H11510488A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997506919A
Other languages
English (en)
Japanese (ja)
Other versions
JP4174563B2 (ja
JPH11510488A (ja
Filing date
Publication date
Priority claimed from US08/505,606 external-priority patent/US5925351A/en
Application filed filed Critical
Publication of JPH11510488A publication Critical patent/JPH11510488A/ja
Publication of JPH11510488A5 publication Critical patent/JPH11510488A5/ja
Application granted granted Critical
Publication of JP4174563B2 publication Critical patent/JP4174563B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP50691997A 1995-07-21 1996-07-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体 Expired - Fee Related JP4174563B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/505,606 US5925351A (en) 1995-07-21 1995-07-21 Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
US08/505,606 1995-07-21
PCT/US1996/012010 WO1997003687A1 (en) 1995-07-21 1996-07-19 SOLUBLE LYMPHOTOXIN-β RECEPTORS AND ANTI-LYMPHOTOXIN RECEPTOR AND LIGAND ANTIBODIES, AS THERAPEUTIC AGENTS FOR THE TREATMENT OF IMMUNOLOGICAL DISEASE

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007161925A Division JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Publications (3)

Publication Number Publication Date
JPH11510488A JPH11510488A (ja) 1999-09-14
JPH11510488A5 true JPH11510488A5 (2) 2004-08-26
JP4174563B2 JP4174563B2 (ja) 2008-11-05

Family

ID=24011046

Family Applications (3)

Application Number Title Priority Date Filing Date
JP50691997A Expired - Fee Related JP4174563B2 (ja) 1995-07-21 1996-07-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2007161925A Withdrawn JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2011209921A Withdrawn JP2012041350A (ja) 1995-07-21 2011-09-26 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2007161925A Withdrawn JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2011209921A Withdrawn JP2012041350A (ja) 1995-07-21 2011-09-26 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Country Status (28)

Country Link
US (6) US5925351A (2)
EP (2) EP0840616B1 (2)
JP (3) JP4174563B2 (2)
KR (2) KR100557258B1 (2)
CN (3) CN1146441C (2)
AT (1) ATE279205T1 (2)
AU (1) AU715407B2 (2)
BG (1) BG63330B1 (2)
BR (1) BR9609716A (2)
CA (1) CA2227477A1 (2)
CZ (1) CZ298277B6 (2)
DE (1) DE69633624T2 (2)
DK (1) DK0840616T3 (2)
EA (3) EA001200B1 (2)
EE (1) EE04419B1 (2)
ES (1) ES2225889T3 (2)
FI (1) FI980122A7 (2)
HU (1) HU227508B1 (2)
MX (1) MX9800624A (2)
NO (2) NO327163B1 (2)
NZ (2) NZ503818A (2)
PL (1) PL186911B1 (2)
PT (1) PT840616E (2)
RO (1) RO121799B1 (2)
SI (1) SI0840616T1 (2)
SK (1) SK286409B6 (2)
TR (1) TR199800091T1 (2)
WO (1) WO1997003687A1 (2)

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CA2344049C (en) * 1998-10-09 2009-12-15 Biogen, Inc. Reversal of viral-induced systemic shock and respiratory distress by blockade of the lymphotoxin beta pathway
TR200504220T2 (tr) 1998-12-17 2007-04-24 Biogen Idec Ma Inc. Aktif limfotoksin-beta reseptör imunoglobülin şimeAktif limfotoksin-beta reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştrik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.ırılması için bir yöntem.
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MXPA03003144A (es) * 2000-10-13 2004-12-06 Biogen Inc Anticuerpos humanizados anti-lt-??-r.
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JP4429726B2 (ja) * 2002-02-08 2010-03-10 ワイス 炎症性応答を調節するための組成物および方法
CN1678625A (zh) * 2002-07-01 2005-10-05 比奥根艾迪克Ma公司 人源化抗淋巴毒素β受体的抗体
JP2006504775A (ja) * 2002-10-31 2006-02-09 バイオジェン・アイデック・エムエイ・インコーポレイテッド リンホトキシン経路インヒビターによる免疫学的腎障害の処置
JP2006513225A (ja) * 2002-12-20 2006-04-20 バイオジェン・アイデック・エムエイ・インコーポレイテッド 化学療法剤と組み合わせたリンホトキシンβ受容体因子
CA2511013A1 (en) * 2002-12-20 2004-07-15 Biogen Idec Ma Inc. Multivalent lymphotoxin beta receptor agonists and therapeutic uses thereof
CA2529945A1 (en) * 2003-06-27 2005-01-06 Biogen Idec Ma Inc. Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions
WO2005067477A2 (en) * 2003-12-08 2005-07-28 Centocor, Inc. Anti-human lymphotoxin alpha antibodies, compositions, methods and uses
AU2005227322A1 (en) * 2004-03-23 2005-10-06 Biogen Idec Ma Inc. Receptor coupling agents and therapeutic uses thereof
AU2005271403A1 (en) * 2004-08-03 2006-02-16 Biorexis Pharmaceutical Corporation Combination therapy using transferrin fusion proteins comprising GLP-1
WO2006074399A2 (en) * 2005-01-05 2006-07-13 Biogen Idec Ma Inc. Multispecific binding molecules comprising connecting peptides
WO2006135660A2 (en) * 2005-06-10 2006-12-21 University Of Chicago Therapies involving lymphotoxin beta receptor
CA2624730A1 (en) * 2005-10-04 2007-04-12 The John Hopkins University Compositions and methods for treating inflammation
WO2007109733A2 (en) 2006-03-21 2007-09-27 The Johns Hopkins University Diagnostic and prognostic markers and treatment strategies for multiple sclerosis
WO2008012629A2 (en) * 2006-07-24 2008-01-31 Biorexis Pharmaceutical Corporation Exendin fusion proteins
KR20090078349A (ko) 2006-10-12 2009-07-17 제넨테크, 인크. 림포톡신-알파에 대한 항체
JP2010506955A (ja) * 2006-10-20 2010-03-04 バイオジェン・アイデック・エムエイ・インコーポレイテッド 可溶性リンホトキシンβレセプターによる脱髄障害の処置
US8338376B2 (en) * 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
KR20170012582A (ko) 2006-11-02 2017-02-02 악셀레론 파마 인코포레이티드 Alk1 수용체 및 리간드 길항제 및 그의 용도
US8440185B2 (en) 2006-12-26 2013-05-14 The Johns Hopkins University Compositions and methods for the treatment of immunologic disorders
JP5431171B2 (ja) * 2007-03-15 2014-03-05 バイオジェン・アイデック・エムエイ・インコーポレイテッド 自己免疫障害の処置
JP5719591B2 (ja) 2007-06-08 2015-05-20 バイオジェン アイデック エムエー インコーポレイティドBiogen Idec Inc. 抗tnf応答性または非応答性を予測するためのバイオマーカー
JP2012514458A (ja) * 2008-12-31 2012-06-28 バイオジェン・アイデック・エムエイ・インコーポレイテッド 抗リンホトキシン抗体
EP3303383A1 (en) 2015-06-05 2018-04-11 iBio, Inc. Endostatin fragments and variants for use in treating fibrosis
EP3807401A1 (en) * 2018-06-15 2021-04-21 Universität Bern LIGANDS TO LIGHT OR ITS RECEPTOR LTßR FOR USE IN HAEMATOLOGIC MALIGNANCIES
US12146160B2 (en) 2019-05-14 2024-11-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Regulatory T cells targeted by lymphotoxin alpha blocking agent and uses thereof
CA3228786A1 (en) 2021-08-25 2023-03-02 Ibio, Inc. Anti-cd25 antibody

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MXPA03003144A (es) * 2000-10-13 2004-12-06 Biogen Inc Anticuerpos humanizados anti-lt-??-r.
CN1678625A (zh) * 2002-07-01 2005-10-05 比奥根艾迪克Ma公司 人源化抗淋巴毒素β受体的抗体
JP2006513225A (ja) * 2002-12-20 2006-04-20 バイオジェン・アイデック・エムエイ・インコーポレイテッド 化学療法剤と組み合わせたリンホトキシンβ受容体因子
CA2511013A1 (en) * 2002-12-20 2004-07-15 Biogen Idec Ma Inc. Multivalent lymphotoxin beta receptor agonists and therapeutic uses thereof
AU2005227322A1 (en) * 2004-03-23 2005-10-06 Biogen Idec Ma Inc. Receptor coupling agents and therapeutic uses thereof
CA2655411A1 (en) 2006-06-15 2007-12-21 Biogen Idec Ma Inc. Combination therapy employing lymphotoxin beta receptor binding molecules in combination with second agents

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