JPH11512608A5 - - Google Patents

Info

Publication number
JPH11512608A5
JPH11512608A5 JP1997513637A JP51363797A JPH11512608A5 JP H11512608 A5 JPH11512608 A5 JP H11512608A5 JP 1997513637 A JP1997513637 A JP 1997513637A JP 51363797 A JP51363797 A JP 51363797A JP H11512608 A5 JPH11512608 A5 JP H11512608A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP1997513637A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11512608A (ja
Filing date
Publication date
Priority claimed from US08/534,351 external-priority patent/US6162796A/en
Application filed filed Critical
Publication of JPH11512608A publication Critical patent/JPH11512608A/ja
Publication of JPH11512608A5 publication Critical patent/JPH11512608A5/ja
Abandoned legal-status Critical Current

Links

JP9513637A 1995-09-27 1996-09-26 Ａａｖベクターを用いて心臓に遺伝子を導入する方法 Abandoned JPH11512608A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/534,351 1995-09-27
US08/534,351 US6162796A (en) 1995-09-27 1995-09-27 Method for transferring genes to the heart using AAV vectors
PCT/US1996/015446 WO1997012050A1 (en) 1995-09-27 1996-09-26 Method for transferring genes to the heart using aav vectors

Publications (2)

Publication Number Publication Date
JPH11512608A JPH11512608A (ja) 1999-11-02
JPH11512608A5 true JPH11512608A5 (2) 2004-09-30

Family

ID=24129676

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9513637A Abandoned JPH11512608A (ja) 1995-09-27 1996-09-26 Ａａｖベクターを用いて心臓に遺伝子を導入する方法

Country Status (7)

Country Link
US (1) US6162796A (2)
EP (1) EP0859853A1 (2)
JP (1) JPH11512608A (2)
AU (1) AU727835B2 (2)
CA (1) CA2233167A1 (2)
WO (1) WO1997012050A1 (2)
ZA (1) ZA968170B (2)

Families Citing this family (41)

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US6306830B1 (en) 1996-09-05 2001-10-23 The Regents Of The University Of California Gene therapy for congestive heart failure
US6752987B1 (en) 1995-02-28 2004-06-22 The Regents Of The University Of California Adenovirus encoding human adenylylcyclase (AC) VI
US7745416B2 (en) * 1995-04-11 2010-06-29 The Regents Of The University Of California Method for in vivo regulation of cardiac muscle contractility
CA2223837C (en) * 1995-06-07 2010-05-25 University Of North Carolina At Chapel Hill Aav transduction of myoblasts
US6506379B1 (en) 1995-06-07 2003-01-14 Ariad Gene Therapeutics, Inc. Intramuscular delivery of recombinant AAV
US20030206891A1 (en) * 1995-06-07 2003-11-06 Ariad Gene Therapeutics, Inc. Rapamycin-based biological regulation
US5962313A (en) * 1996-01-18 1999-10-05 Avigen, Inc. Adeno-associated virus vectors comprising a gene encoding a lyosomal enzyme
US5858351A (en) 1996-01-18 1999-01-12 Avigen, Inc. Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors
US5846528A (en) * 1996-01-18 1998-12-08 Avigen, Inc. Treating anemia using recombinant adeno-associated virus virions comprising an EPO DNA sequence
WO1997032990A1 (en) * 1996-03-04 1997-09-12 Targeted Genetics Corporation Methods for transducing cells in blood vessels using recombinant aav vectors
US20020037867A1 (en) * 1999-02-26 2002-03-28 James M. Wilson Method for recombinant adeno-associated virus-directed gene therapy
EP0932418B1 (en) * 1996-09-06 2007-12-05 The Trustees Of The University Of Pennsylvania Method for recombinant adeno-associated virus-directed gene therapy
US6486133B1 (en) 1997-03-07 2002-11-26 The Wistar Institute Of Anatomy And Biology Methods for inducing localized vascular development and enhancing the repair of a wound in the mammamian dermis
US6995006B2 (en) * 1997-09-05 2006-02-07 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
US6953690B1 (en) 1998-03-20 2005-10-11 The Trustees Of The University Of Pennsylvania Compositions and methods for helper-free production of recombinant adeno-associated viruses
US6129757A (en) * 1998-05-18 2000-10-10 Scimed Life Systems Implantable members for receiving therapeutically useful compositions
AU763049B2 (en) * 1998-12-28 2003-07-10 Arch Development Corporation Efficient and stable (in vivo) gene transfer to cardiomyocytes using recombinantadeno-associated virus vectors
US7078387B1 (en) 1998-12-28 2006-07-18 Arch Development Corp. Efficient and stable in vivo gene transfer to cardiomyocytes using recombinant adeno-associated virus vectors
JP4693244B2 (ja) 1999-03-18 2011-06-01 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法
CA2395839A1 (en) 1999-12-27 2001-07-05 The Regents Of The University Of California Gene therapy for congestive heart failure
US20030144237A1 (en) * 2000-04-13 2003-07-31 Peter Carmeliet Use of inhibition of a gas6 function or of a gas6 receptor for preventing and treating a cardiovascular disease
EP1870473A1 (en) * 2000-08-17 2007-12-26 Keiya Ozawa Adeno-associated virus-mediated delivery of angiogenic factors
CA2419245A1 (en) * 2000-08-17 2002-02-21 Keiya Ozawa Adeno-associated virus-mediated delivery of angiogenic factors
WO2002080756A2 (en) * 2001-04-05 2002-10-17 The Johns Hopkins University Imaging systems for in vivo protocols
AU2002303243A1 (en) * 2001-04-05 2002-10-21 The Johns Hopkins University Imaging nucleic acid delivery
US7217570B2 (en) 2001-08-23 2007-05-15 The Wistar Institute Of Anatomy And Biology Organotypic intestinal culture and methods of use thereof
WO2003084390A2 (en) * 2002-04-01 2003-10-16 The Johns Hopkins University School Of Medicine Device, systems and methods for heating of a vessel in combination with mr/nmr imaging
US20040009151A1 (en) * 2002-04-04 2004-01-15 Kay Mark A. Methods for delivering recombinant adeno-associated virus virions to the liver of a mammal
EP1486567A1 (en) * 2003-06-11 2004-12-15 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Improved adeno-associated virus (AAV) vector for gene therapy
WO2005027995A2 (en) * 2003-09-19 2005-03-31 The Trustees Of The University Of Pennsylvania Global myocardial perfusion catheter
US20060128647A1 (en) * 2003-12-24 2006-06-15 Daniel Sigg Novel oligonucleotides and treating cardiac disorders by using the same
US8859273B2 (en) * 2003-12-24 2014-10-14 Medtronic, Inc. Methods of using HCN genes to treat cardiac arrhythmias
US20050244377A1 (en) * 2003-12-24 2005-11-03 Daniel Sigg Methods of treating cardiac disorders by suppressing the expression of the potassium inwardly-rectifying channel
US20050281786A1 (en) * 2004-06-18 2005-12-22 David Poulsen AAV mediated gene delivery to cochlear cells
CN1286981C (zh) * 2004-11-30 2006-11-29 华中科技大学同济医学院附属同济医院 表达人类cyp2j2反义基因的重组腺相关病毒及其制备方法
KR20090035711A (ko) * 2006-07-25 2009-04-10 셀라돈 코포레이션 유전자 치료를 위한 아데노-관련 바이러스 벡터의 전방 심외막 관상에의 연장 주입
KR20100129295A (ko) 2008-02-19 2010-12-08 셀라돈 코포레이션 심근 내 바이러스 벡터의 흡수를 개선시키기 위한 조성물
US9644205B2 (en) 2012-04-25 2017-05-09 The Regents Of The University Of California Synthetic promoter for modulating gene expression
US10648000B2 (en) 2015-02-16 2020-05-12 University Of Florida Research Foundation, Incorporated rAAV vector compositions, methods for targeting vascular endothelial cells and use in treatment of type I diabetes
DK3405215T3 (da) * 2016-01-19 2022-09-19 Univ California Fremgangsmåder til behandling af danon-sygdom og andre autofagilidelser
US12460226B2 (en) 2018-04-16 2025-11-04 The Trustees Of The University Of Pennsylvania Compositions and methods for treating duchenne muscular dystrophy

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5139941A (en) * 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
US5252479A (en) * 1991-11-08 1993-10-12 Research Corporation Technologies, Inc. Safe vector for gene therapy
US5478745A (en) * 1992-12-04 1995-12-26 University Of Pittsburgh Recombinant viral vector system
WO1995012681A1 (en) * 1993-11-05 1995-05-11 New York University Methods relating to ir-95
PT728214E (pt) * 1993-11-09 2004-11-30 Ohio Med College Linhas celulares estaveis capazes de expressar o gene de replicacao do virus adeno-associado
US5693531A (en) * 1993-11-24 1997-12-02 The United States Of America As Represented By The Department Of Health And Human Services Vector systems for the generation of adeno-associated virus particles
US5580766A (en) * 1994-01-14 1996-12-03 Alexion Pharmaceuticals, Inc. Retroviral vector particles for transducing non-proliferating cells
FR2716682B1 (fr) * 1994-01-28 1996-04-26 Centre Nat Rech Scient Procédé de préparation de virus adéno-associés (AAV) recombinants et utilisations.
DE9416814U1 (de) * 1994-10-19 1996-02-15 Pöting GmbH & Co. KG, 40699 Erkrath Vorrichtung zur Herstellung von Glasformlingen nach dem Preßverfahren
WO1996026742A1 (en) * 1995-02-28 1996-09-06 The Regents Of The University Of California Gene transfer-mediated angiogenesis therapy
US5797870A (en) * 1995-06-07 1998-08-25 Indiana University Foundation Pericardial delivery of therapeutic and diagnostic agents

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