JPH11514843A - 喘息の治療方法 - Google Patents

喘息の治療方法

Info

Publication number: JPH11514843A
Authority: JP; Japan
Prior art keywords: antisense oligonucleotide; adenosine receptor; particles; adenosine; bond
Prior art date: 1995-06-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

JP9500962A

Other languages

English (en)

Japanese (ja)

Other versions

JPH11514843A5 (2

Inventor

ジョナサンダブリュー．ナイス

Original Assignee

イーストキャロライナユニバーシティー

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-07

Filing date

1996-06-03

Publication date

1999-12-21

1996-06-03 Application filed by イーストキャロライナユニバーシティー filed Critical イーストキャロライナユニバーシティー

1999-12-21 Publication of JPH11514843A publication Critical patent/JPH11514843A/ja

2004-07-22 Publication of JPH11514843A5 publication Critical patent/JPH11514843A5/ja

Status Ceased legal-status Critical Current

Links

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CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 description 1
229940029284 trichlorofluoromethane Drugs 0.000 description 1
239000003981 vehicle Substances 0.000 description 1
239000000341 volatile oil Substances 0.000 description 1
230000003442 weekly effect Effects 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
General Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Pulmonology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Microbiology (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Plant Pathology (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)

JP9500962A 1995-06-07 1996-06-03 喘息の治療方法 Ceased JPH11514843A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US08/472,527		1995-06-07
US08/472,527 US6040296A (en)	1995-06-07	1995-06-07	Specific antisense oligonucleotide composition & method for treatment of disorders associated with bronchoconstriction and lung inflammation
PCT/US1996/008325 WO1996040266A1 (en)	1995-06-07	1996-06-03	Method of treatment for asthma

Publications (2)

Publication Number	Publication Date
JPH11514843A true JPH11514843A (ja)	1999-12-21
JPH11514843A5 JPH11514843A5 (2)	2004-07-22

Family

ID=23875872

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP9500962A Ceased JPH11514843A (ja)	1995-06-07	1996-06-03	喘息の治療方法

Country Status (6)

Country	Link
US (1)	US6040296A (2)
EP (1)	EP0831924A4 (2)
JP (1)	JPH11514843A (2)
CN (1)	CN1192158A (2)
CA (1)	CA2223769C (2)
WO (1)	WO1996040266A1 (2)

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1995
- 1995-06-07 US US08/472,527 patent/US6040296A/en not_active Expired - Fee Related
1996
- 1996-06-03 CN CN96195955A patent/CN1192158A/zh active Pending
- 1996-06-03 WO PCT/US1996/008325 patent/WO1996040266A1/en not_active Ceased
- 1996-06-03 JP JP9500962A patent/JPH11514843A/ja not_active Ceased
- 1996-06-03 EP EP96917910A patent/EP0831924A4/en not_active Withdrawn
- 1996-06-03 CA CA002223769A patent/CA2223769C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US6040296A (en)	2000-03-21
CA2223769C (en)	2002-01-29
WO1996040266A1 (en)	1996-12-19
EP0831924A4 (en)	2001-11-14
AU699330B2 (en)	1998-12-03
CA2223769A1 (en)	1996-12-19
CN1192158A (zh)	1998-09-02
MX9709865A (es)	1998-08-30
AU6029596A (en)	1996-12-30
EP0831924A1 (en)	1998-04-01

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Publication	Publication Date	Title
JPH11514843A (ja)	1999-12-21	喘息の治療方法
US6025339A (en)	2000-02-15	Composition, kit and method for treatment of disorders associated with bronchoconstriction and lung inflammation
US5994315A (en)	1999-11-30	Low adenosine agent, composition, kit and method for treatment of airway disease
KR20010030622A (ko)	2001-04-16	다중 표적 하이브리드형성 핵산과 그들의 제조, 구성,제제, 키트 및 응용
WO1998023294A9 (en)	1998-09-17	Agent and method of treatment for diseases and conditions associated with respiratory ailments and lung inflammation
US6825174B2 (en)	2004-11-30	Composition, formulations & method for prevention & treatment of diseases and conditions associated with bronchoconstriction, allergy(ies) & inflammation
EP1011608A2 (en)	2000-06-28	Composition and method for prevention and treatment of cardiopulmonary and renal failure or damage associated with ischemia, endotoxin release, ards or brought about by administration of certain drugs
JP2002518007A (ja)	2002-06-25	アトピー性疾患および新生物細胞増殖を治療または予防するためのアンチセンスオリゴヌクレオチド
EP1165093A1 (en)	2002-01-02	Method for validating/invalidating target(s) and pathways
AU699330C (en)	2000-02-10	Method of treatment for asthma
AU724817B2 (en)	2000-09-28	Method of treatment for asthma
AU753972B2 (en)	2002-10-31	Low adenosine oligonucleotide, composition, kit and methods for obtaining oligonucleotide and for treatment of airway disease(s)
US20050014711A1 (en)	2005-01-20	Composition, formulations & methods for prevention and treatment of diseases and conditions associated with bronchoconstriction, allergy(ies) and inflammation
MXPA97009865A (en)	1998-11-12	Method of treatment for a
HK1023952A (en)	2000-09-29	Agent and method of treatment for diseases and conditions associated with respiratory ailments and lung inflammation
HK1016469A (en)	1999-11-05	Method of treatment for asthma
EP1766013B1 (en)	2011-06-08	Nuclease resistant external guide sequences for treating inflammatory and viral related respiratory diseases
MXPA97009866A (en)	1998-11-12	Method for the treatment of pulmon diseases using oligonucleotides antisent
CA2330545C (en)	2009-12-15	Antisense oligonucleotides for treating or preventing atopic diseases and neoplastic cell proliferation
KR20020095600A (ko)	2002-12-28	아데노신 함량이 낮은 안티센스 올리고뉴클레오타이드,조성물, 키트 및 기관지수축, 폐염증, 알레르기(들) 및계면활성제 결핍와 관련된 기도 장애들의 치료 방법
MXPA00004001A (es)	2002-08-20	Composicion y metodo para la prevencion y tratamiento de insuficiencia o dano cardiopulmonar y renal asociado con isquemia, liberacion de endotoxinas, sindrome de esfuerzo respiratorio agudo o provocado por la administracion de ciertos farmacos.
MXPA00002640A (en)	2001-12-13	Multiple target hybridizing nucleic acids, their preparation, compositions, formulation, kits and applications