JPS51113841A - Process for preparing lower alkyl esters of n-formyl-alpha -l-aspartyl-l-phenylalanine - Google Patents
Process for preparing lower alkyl esters of n-formyl-alpha -l-aspartyl-l-phenylalanineInfo
- Publication number
- JPS51113841A JPS51113841A JP3763875A JP3763875A JPS51113841A JP S51113841 A JPS51113841 A JP S51113841A JP 3763875 A JP3763875 A JP 3763875A JP 3763875 A JP3763875 A JP 3763875A JP S51113841 A JPS51113841 A JP S51113841A
- Authority
- JP
- Japan
- Prior art keywords
- aspartyl
- formyl
- phenylalanine
- lower alkyl
- alkyl esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- WYYUBJAMROQJSF-QWRGUYRKSA-N (3s)-4-[[(1s)-1-carboxy-2-phenylethyl]amino]-3-formamido-4-oxobutanoic acid Chemical compound OC(=O)C[C@H](NC=O)C(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 WYYUBJAMROQJSF-QWRGUYRKSA-N 0.000 title abstract 2
- 125000005907 alkyl ester group Chemical group 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
PURPOSE: Lower alkyl esters of N-formyl-α-L-aspartyl-L-phenylalanine, the raw material for sweeterner, are obtained in good yield from easily preparable N-formyl-N-aspartyl anhydride.
COPYRIGHT: (C)1976,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3763875A JPS51113841A (en) | 1975-03-28 | 1975-03-28 | Process for preparing lower alkyl esters of n-formyl-alpha -l-aspartyl-l-phenylalanine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3763875A JPS51113841A (en) | 1975-03-28 | 1975-03-28 | Process for preparing lower alkyl esters of n-formyl-alpha -l-aspartyl-l-phenylalanine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS51113841A true JPS51113841A (en) | 1976-10-07 |
Family
ID=12503178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3763875A Pending JPS51113841A (en) | 1975-03-28 | 1975-03-28 | Process for preparing lower alkyl esters of n-formyl-alpha -l-aspartyl-l-phenylalanine |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS51113841A (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2516077A1 (en) * | 1981-11-06 | 1983-05-13 | Human Pharm Sa Laboratoires | PROCESS FOR THE PREPARATION OF ESTER-METHYLIC OF A-ASPARTYL PHENYLALANINE |
| JPS62149699A (en) * | 1985-12-24 | 1987-07-03 | Ajinomoto Co Inc | Production of n-protected-alpha-l-aspartyl-l-phenylalanine methyl ester |
| US4745210A (en) * | 1984-12-17 | 1988-05-17 | Mitsui Toatsu Chemicals, Incorporated | Preparation process of N-formyl-α-aspartyl phenylalanine |
| US4778916A (en) * | 1985-03-26 | 1988-10-18 | Mitsui Toatsu Chemicals, Inc. | Preparation process of α-L-aspartyl-L-phenylalanine methyl ester or hydrochloride thereof |
| US4801732A (en) * | 1984-12-27 | 1989-01-31 | Mitsui Toatsu Chemicals, Incorporated | Preparation process of α-L-aspartyl-L-phenylalanine methyl ester |
| US4918216A (en) * | 1986-12-05 | 1990-04-17 | Mitsui Toatsu Chemicals, Incorporated | Preparation process of α-l-aspartyl-l-phenyl-alanine methyl ester or hydrohalide thereof |
| US4962222A (en) * | 1986-12-19 | 1990-10-09 | Mitsui Toatsu Chemicals, Incorporated | Preparation process of α-l-aspartyl-l-phenylalanine methyl ester having low hygroscopicity |
| WO2008044409A1 (en) | 2006-10-10 | 2008-04-17 | Ajinomoto Co., Inc. | Method for production of l-amino acid |
| DE102008049533A1 (en) | 2007-09-27 | 2009-06-18 | Ajinomoto Co., Inc. | A method for producing amino acids using a bacterium of the family Enterobacteriaceae |
| WO2009088049A1 (en) | 2008-01-10 | 2009-07-16 | Ajinomoto Co., Inc. | Method for production of desired substance by fermentation process |
| WO2011024555A1 (en) | 2009-08-28 | 2011-03-03 | 味の素株式会社 | Process for production of l-amino acid |
| WO2011055710A1 (en) | 2009-11-06 | 2011-05-12 | 味の素株式会社 | Method for producing l-amino acid |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4818249B1 (en) * | 1968-02-19 | 1973-06-05 |
-
1975
- 1975-03-28 JP JP3763875A patent/JPS51113841A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4818249B1 (en) * | 1968-02-19 | 1973-06-05 |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2516077A1 (en) * | 1981-11-06 | 1983-05-13 | Human Pharm Sa Laboratoires | PROCESS FOR THE PREPARATION OF ESTER-METHYLIC OF A-ASPARTYL PHENYLALANINE |
| US4745210A (en) * | 1984-12-17 | 1988-05-17 | Mitsui Toatsu Chemicals, Incorporated | Preparation process of N-formyl-α-aspartyl phenylalanine |
| US4801732A (en) * | 1984-12-27 | 1989-01-31 | Mitsui Toatsu Chemicals, Incorporated | Preparation process of α-L-aspartyl-L-phenylalanine methyl ester |
| US4778916A (en) * | 1985-03-26 | 1988-10-18 | Mitsui Toatsu Chemicals, Inc. | Preparation process of α-L-aspartyl-L-phenylalanine methyl ester or hydrochloride thereof |
| JPS62149699A (en) * | 1985-12-24 | 1987-07-03 | Ajinomoto Co Inc | Production of n-protected-alpha-l-aspartyl-l-phenylalanine methyl ester |
| US4918216A (en) * | 1986-12-05 | 1990-04-17 | Mitsui Toatsu Chemicals, Incorporated | Preparation process of α-l-aspartyl-l-phenyl-alanine methyl ester or hydrohalide thereof |
| US4962222A (en) * | 1986-12-19 | 1990-10-09 | Mitsui Toatsu Chemicals, Incorporated | Preparation process of α-l-aspartyl-l-phenylalanine methyl ester having low hygroscopicity |
| WO2008044409A1 (en) | 2006-10-10 | 2008-04-17 | Ajinomoto Co., Inc. | Method for production of l-amino acid |
| DE102008049533A1 (en) | 2007-09-27 | 2009-06-18 | Ajinomoto Co., Inc. | A method for producing amino acids using a bacterium of the family Enterobacteriaceae |
| WO2009088049A1 (en) | 2008-01-10 | 2009-07-16 | Ajinomoto Co., Inc. | Method for production of desired substance by fermentation process |
| EP2749652A2 (en) | 2008-01-10 | 2014-07-02 | Ajinomoto Co., Inc. | A method for producing a target substance by fermentation |
| WO2011024555A1 (en) | 2009-08-28 | 2011-03-03 | 味の素株式会社 | Process for production of l-amino acid |
| WO2011055710A1 (en) | 2009-11-06 | 2011-05-12 | 味の素株式会社 | Method for producing l-amino acid |
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