JPS51113890A - Method for preparing novel cephalosporins - Google Patents

Method for preparing novel cephalosporins

Info

Publication number
JPS51113890A
JPS51113890A JP50037207A JP3720775A JPS51113890A JP S51113890 A JPS51113890 A JP S51113890A JP 50037207 A JP50037207 A JP 50037207A JP 3720775 A JP3720775 A JP 3720775A JP S51113890 A JPS51113890 A JP S51113890A
Authority
JP
Japan
Prior art keywords
preparing novel
cephalosporins
novel cephalosporins
quat
azide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP50037207A
Other languages
Japanese (ja)
Other versions
JPS5320518B2 (en
Inventor
Isamu Saikawa
Shuntaro Takano
Chosaku Yoshida
Okuta Takashima
Kaishu Momoi
Seietsu Kuroda
Miwako Komatsu
Takashi Yasuda
Hiroshi Kodama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Priority to JP50037207A priority Critical patent/JPS51113890A/en
Priority to AU80431/75A priority patent/AU481427B2/en
Priority to IL47168A priority patent/IL47168A/en
Priority to GB15360/77A priority patent/GB1508064A/en
Priority to CY102775A priority patent/CY1027A/en
Priority to GB17557/75A priority patent/GB1508062A/en
Priority to CY102875A priority patent/CY1028A/xx
Priority to CY1026A priority patent/CY1026A/en
Priority to GB1536377A priority patent/GB1508063A/en
Priority to DE2519400A priority patent/DE2519400C3/en
Priority to DE19752559932 priority patent/DE2559932C2/en
Priority to DE2560239A priority patent/DE2560239C2/en
Priority to BE156035A priority patent/BE828692A/en
Priority to PH17137A priority patent/PH21545A/en
Priority to CH584775A priority patent/CH605995A5/xx
Priority to AR258658A priority patent/AR209607A1/en
Priority to FR7514159A priority patent/FR2269937B1/fr
Priority to MX814275U priority patent/MX5699E/en
Priority to NL7505375.A priority patent/NL162386C/en
Priority to MX234875U priority patent/MX2966E/en
Priority to DK201975A priority patent/DK151338C/en
Priority to FI751340A priority patent/FI63760C/en
Priority to DD185922A priority patent/DD117882A5/xx
Priority to HUTO1002A priority patent/HU169633B/hu
Priority to SE7505392A priority patent/SE431457B/en
Priority to CY102976A priority patent/CY1029A/en
Priority to PH18076A priority patent/PH20534A/en
Priority to CA308,161A priority patent/CA1078384A/en
Priority to AR262422A priority patent/AR210879A1/en
Publication of JPS51113890A publication Critical patent/JPS51113890A/en
Priority to US05/732,860 priority patent/US4110327A/en
Priority to FR7631895A priority patent/FR2320295A1/en
Priority to AT828976A priority patent/AT344906B/en
Priority to PH19129A priority patent/PH22336A/en
Priority to PH19128A priority patent/PH22346A/en
Priority to IN2122/CAL/76A priority patent/IN145444B/en
Priority to IN2121/CAL/76A priority patent/IN145443B/en
Priority to ES454265A priority patent/ES454265A1/en
Priority to PH19814A priority patent/PH21987A/en
Priority to US05/841,608 priority patent/US4410522A/en
Priority to IL53485A priority patent/IL53485A0/en
Priority to CH1607577A priority patent/CH616939A5/en
Priority to FI780330A priority patent/FI62833C/en
Publication of JPS5320518B2 publication Critical patent/JPS5320518B2/ja
Priority to SE7808204A priority patent/SE435062B/en
Priority to KE2923A priority patent/KE2923A/en
Priority to DK104979A priority patent/DK149950C/en
Priority to HK262/79A priority patent/HK26279A/en
Priority to US06/047,818 priority patent/US4327097A/en
Priority to DK95880A priority patent/DK151958C/en
Priority to FI810165A priority patent/FI65780C/en
Priority to FI810468A priority patent/FI62834C/en
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: Cephalosporins of formula I are new: [where R is amino acid residue; R1 is H, carboxy-protecting group of salt-forming cation; n is 1W3; X is O or S; m is equal to 4Wn; R2 and R3 are a pair of substituents such as H, halogen carboxyl and alkyl, etc. at the same carbon respectively; A is H or hydroxy; B is R5 (R5 is cyano, azide or an organic residue which is bonded to CH2 via O, N or S) or quat-ammonium].
COPYRIGHT: (C)1976,JPO&Japio
JP50037207A 1974-05-09 1975-03-27 Method for preparing novel cephalosporins Granted JPS51113890A (en)

Priority Applications (50)

Application Number Priority Date Filing Date Title
JP50037207A JPS51113890A (en) 1975-03-27 1975-03-27 Method for preparing novel cephalosporins
AU80431/75A AU481427B2 (en) 1974-05-13 1975-04-23 Novel penicillins and cephalosporins and process for producing same
IL47168A IL47168A (en) 1974-05-09 1975-04-24 Mono or dioxo piperazino(thio)carbonylamino derivatives ofpenicillins and cephalosporins and process for producing the same
GB15360/77A GB1508064A (en) 1974-05-09 1975-04-28 Amino acid derivatives
CY102775A CY1027A (en) 1974-05-09 1975-04-28 2,3-dioxopiperazine derivatives
GB17557/75A GB1508062A (en) 1974-05-09 1975-04-28 Penicillins and cephalosporins and process for producing the same
CY102875A CY1028A (en) 1974-05-09 1975-04-28
CY1026A CY1026A (en) 1974-05-09 1975-04-28 Penicillins abd cephalosporins and process for producing the same
GB1536377A GB1508063A (en) 1974-05-09 1975-04-28 2,3-dioxopiperazine derivatives
DE2519400A DE2519400C3 (en) 1974-05-09 1975-04-30 Penicillin compounds, processes for preparing the same, and compositions containing the same
DE19752559932 DE2559932C2 (en) 1974-05-09 1975-04-30 Cephalosporins, processes for making the same, and compositions containing the same
DE2560239A DE2560239C2 (en) 1974-05-09 1975-04-30 2,3-Dioxopiperazine derivatives and processes for their preparation
BE156035A BE828692A (en) 1974-05-09 1975-05-02 NEW PENICILLINS AND CEPHALOSPORINS, THEIR METHOD OF PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
PH17137A PH21545A (en) 1974-05-09 1975-05-05 Novel penicillins and pharmaceutically acceptable salts thereof which contain a mono- or di- oxo piperazino (thio)-carbonyl amino group in molecule
CH584775A CH605995A5 (en) 1974-05-09 1975-05-06
AR258658A AR209607A1 (en) 1974-05-09 1975-05-06 PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 2,3-D OXO-1-PIPERAZINE-CARBONYLAMINE-ACETAMIDO-PENNYLAMINE OR 2,3-DIOXO-1-PIPERAZINOCARBONYLAMINE-ACETAMIDO-DELTA3-CEFEM-4-CARBOXYL ACID
FR7514159A FR2269937B1 (en) 1974-05-09 1975-05-06
MX814275U MX5699E (en) 1975-03-27 1975-05-07 A PROCEDURE FOR THE PREPARATION OF 7-ACILAMINOCEPPHALOSPORANIC ACID DERIVATIVES
NL7505375.A NL162386C (en) 1974-05-09 1975-05-07 METHOD FOR THE PREPARATION OF A PREPARATION WITH ANTI-BACTERIAL ACTION AND PROCESS FOR THE PREPARATION OF COMPOUNDS SUITABLE FOR INCLUSION IN SUCH A PREPARATION.
MX234875U MX2966E (en) 1974-08-13 1975-05-07 PROCEDURE FOR PREPARING PENICILLINS AND CEPHALOSPORINS
DK201975A DK151338C (en) 1974-05-09 1975-05-07 METHOD OF ANALOGUE FOR THE PREPARATION OF RACEMIC OR OPTICALLY ACTIVE PENICILLIN OR CEPHALOSPORINES
FI751340A FI63760C (en) 1974-05-09 1975-05-07 FREQUENCY REQUIREMENT FOR THERAPEUTIC THERAPEUTIC PENICILLINER
DD185922A DD117882A5 (en) 1974-05-09 1975-05-08
HUTO1002A HU169633B (en) 1974-05-09 1975-05-08
SE7505392A SE431457B (en) 1974-05-09 1975-05-09 PROCEDURE FOR PREPARING NEW PENICILLINES
CY102976A CY1029A (en) 1974-05-09 1976-01-19 Cephalosporins and process for producing the same
PH18076A PH20534A (en) 1974-05-09 1976-02-10 Novel cephalosporins having a mono or d-oxo-piperazino-carbonyl groups in the molecule and a pharmaceutical composition thereof
CA308,161A CA1078384A (en) 1974-05-09 1976-02-12 2,3-dioxopiperazine derivatives
AR262422A AR210879A1 (en) 1975-03-27 1976-02-27 PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 2,3-DIOXO-1-PIPERAZINOCARBOINIL-AMION -CECEFEM-4-CARBOXYL ACID
US05/732,860 US4110327A (en) 1974-05-09 1976-10-15 2,3 Diketo-piperazinocarbonylamino alkanoic acids and derivatives
FR7631895A FR2320295A1 (en) 1974-05-09 1976-10-22 NEW DERIVATIVES OF 2,3-DIOXOPIPERAZINE AND THEIR PREPARATION PROCESS
AT828976A AT344906B (en) 1974-05-09 1976-11-08 PROCESS FOR PRODUCING NEW CEPHALOSPORINE COMPOUNDS
PH19129A PH22336A (en) 1974-05-09 1976-11-15 A reactive derivative of 2,3-dioxapiperazine derivative
PH19128A PH22346A (en) 1974-05-09 1976-11-15 2,3-dioxo-piperazino carbonylamino alkanoic acid
IN2122/CAL/76A IN145444B (en) 1974-05-09 1976-11-27
IN2121/CAL/76A IN145443B (en) 1974-05-09 1976-11-27
ES454265A ES454265A1 (en) 1975-03-27 1976-12-15 A PROCEDURE FOR OBTAINING NEW CEPHALOSPORINS.
PH19814A PH21987A (en) 1974-05-09 1977-05-25 Process for producing novel penicillins and cephalosporins
US05/841,608 US4410522A (en) 1974-05-09 1977-10-12 Cephalosporins
IL53485A IL53485A0 (en) 1974-05-09 1977-11-29 2,3-dioxypiperazine derivatives
CH1607577A CH616939A5 (en) 1974-05-09 1977-12-27 Process for the preparation of new cephalosporins
FI780330A FI62833C (en) 1974-05-09 1978-02-01 SOM MELLAN PROCEDURES WITH FRAMSTATION OF ANTIBACTERIA WITH PENICILLIN AND OXYCALOSPORINDERIVAT ANVAENDBARA 2,3-DIOXOPIPERAZINDERIVAT OCH FOERFARANDE FOER FRAMSTAELLNING AV DEM
SE7808204A SE435062B (en) 1974-05-09 1978-07-27 PROCEDURE FOR THE PREPARATION OF NEW CEPHALOSPORINES
KE2923A KE2923A (en) 1974-05-09 1979-03-01 Novel penicillins and cephalosporine and process for producing the same
DK104979A DK149950C (en) 1974-05-09 1979-03-14 2,3-DIOXOPIPERAZINOCARBOXYLIC ACID DERIVATIVES FOR USE AS INTERMEDIATES
HK262/79A HK26279A (en) 1974-05-09 1979-04-26 Novel penicillins and cephalosporins and process for producing the same
US06/047,818 US4327097A (en) 1974-05-09 1979-06-12 Novel penicillins
DK95880A DK151958C (en) 1974-05-09 1980-03-06 2,3-DIOXOPIPERAZINE DERIVATIVES FOR USE AS INTERMEDIATES
FI810165A FI65780C (en) 1974-05-09 1981-01-21 FRAMEWORK FOR THERAPEUTIC TREATMENT OF THERAPEUTIC EQUIPMENT
FI810468A FI62834C (en) 1974-05-09 1981-02-16 BUTTER PROCESSING OF ANTIBACTERIA WITH PENICILLIN- OR CHPHALOSPORINDERIVAT ANVAENDBARA 2,3-DIOXOPIPERAZINDERIVAT OCH FOERFARANDE FOER DERAS FRAMSTAELLNING

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50037207A JPS51113890A (en) 1975-03-27 1975-03-27 Method for preparing novel cephalosporins

Publications (2)

Publication Number Publication Date
JPS51113890A true JPS51113890A (en) 1976-10-07
JPS5320518B2 JPS5320518B2 (en) 1978-06-27

Family

ID=12491132

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50037207A Granted JPS51113890A (en) 1974-05-09 1975-03-27 Method for preparing novel cephalosporins

Country Status (3)

Country Link
JP (1) JPS51113890A (en)
AR (1) AR210879A1 (en)
ES (1) ES454265A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5422391A (en) * 1977-07-21 1979-02-20 Toyama Chem Co Ltd Preparation of novel 7alpha-methoxycephalosporins

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5422391A (en) * 1977-07-21 1979-02-20 Toyama Chem Co Ltd Preparation of novel 7alpha-methoxycephalosporins

Also Published As

Publication number Publication date
JPS5320518B2 (en) 1978-06-27
ES454265A1 (en) 1977-12-01
AR210879A1 (en) 1977-09-30

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