JPS5294414A - Production of stable solid composition or complex containing salicylic acid choline * solid dosage form containing same as effective component and use of same - Google Patents
Production of stable solid composition or complex containing salicylic acid choline * solid dosage form containing same as effective component and use of sameInfo
- Publication number
- JPS5294414A JPS5294414A JP631977A JP631977A JPS5294414A JP S5294414 A JPS5294414 A JP S5294414A JP 631977 A JP631977 A JP 631977A JP 631977 A JP631977 A JP 631977A JP S5294414 A JPS5294414 A JP S5294414A
- Authority
- JP
- Japan
- Prior art keywords
- same
- production
- dosage form
- salicylic acid
- effective component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
- A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Novel cholinesalicylate-carboxy-lower alkyl-cellulose-metal complexes are obtained by forming an aqueous solution of a carboxy-lower alkyl-cellulose and cholinesalicylate, adding a source of a physiologically tolerated, at least doubly charged, metal ion in a quantity such that a complex is formed of the components, allowing the reaction mixture to stand until it thickens, and subsequently drying it. The novel compounds are stable, pharmaceutically active, cholinesalicylate compounds.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65111076A | 1976-01-21 | 1976-01-21 | |
| US651110 | 1976-01-21 | ||
| US705056 | 1976-07-14 | ||
| US05/705,056 US4067974A (en) | 1976-01-21 | 1976-07-14 | Stabilized solid form choline salicylate compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5294414A true JPS5294414A (en) | 1977-08-09 |
| JPS6051449B2 JPS6051449B2 (en) | 1985-11-14 |
Family
ID=27096002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52006319A Expired JPS6051449B2 (en) | 1976-01-21 | 1977-01-21 | Stable solid drug containing choline salicylate and method for producing the same |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS6051449B2 (en) |
| AR (1) | AR217249A1 (en) |
| AU (1) | AU511510B2 (en) |
| CA (1) | CA1070299A (en) |
| CH (1) | CH635816A5 (en) |
| DD (1) | DD128908A5 (en) |
| DE (2) | DE2760284C2 (en) |
| DK (1) | DK149804C (en) |
| EG (1) | EG12511A (en) |
| ES (1) | ES454712A1 (en) |
| FI (1) | FI56770C (en) |
| FR (1) | FR2338705A1 (en) |
| GB (2) | GB1575977A (en) |
| GR (1) | GR62110B (en) |
| HU (1) | HU175973B (en) |
| IL (1) | IL50992A (en) |
| MX (1) | MX5920E (en) |
| NL (1) | NL183821C (en) |
| NO (1) | NO145295C (en) |
| NZ (1) | NZ182810A (en) |
| RO (1) | RO71764A (en) |
| SE (1) | SE418799B (en) |
| YU (1) | YU40159B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5043168A (en) * | 1990-04-26 | 1991-08-27 | Sidmak Laboratories, Inc. | Solid choline magnesium salicylate composition and method of preparing same |
| US5217965A (en) * | 1991-06-17 | 1993-06-08 | Euroceltique, S.A. | Stabilized solid dosage forms of choline metal carboxymethylcellulose salicylate compositions |
| USD843660S1 (en) | 2017-11-27 | 2019-03-19 | Mary Kay Inc. | Cosmetic compact |
| USD850006S1 (en) | 2017-11-27 | 2019-05-28 | Mary Kay Inc. | Cosmetic compact |
| USD863685S1 (en) | 2017-11-27 | 2019-10-15 | Mary Kay Inc. | Cosmetic compact |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3347744A (en) * | 1963-10-25 | 1967-10-17 | Smith Kline French Lab | Magnesium hydroxide suspensions |
| US3297529A (en) * | 1964-11-25 | 1967-01-10 | Sutton Lab Inc | Magnesium sulfate stabilized choline salicylate |
| US3326760A (en) * | 1966-05-17 | 1967-06-20 | Synergistics Inc | Choline salicylate polygalacturonate therapy |
| US3759980A (en) * | 1969-05-26 | 1973-09-18 | Stockton Chemicals Inc | Salicylates |
-
1976
- 1976-09-08 CA CA260,766A patent/CA1070299A/en not_active Expired
- 1976-11-25 IL IL50992A patent/IL50992A/en unknown
- 1976-12-06 NZ NZ182810A patent/NZ182810A/en unknown
- 1976-12-07 GR GR52348A patent/GR62110B/en unknown
- 1976-12-22 AR AR265966A patent/AR217249A1/en active
- 1976-12-23 SE SE7614538A patent/SE418799B/en not_active IP Right Cessation
- 1976-12-30 FI FI763741A patent/FI56770C/en not_active IP Right Cessation
- 1976-12-30 ES ES454712A patent/ES454712A1/en not_active Expired
-
1977
- 1977-01-10 CH CH25977A patent/CH635816A5/en not_active IP Right Cessation
- 1977-01-12 YU YU69/77A patent/YU40159B/en unknown
- 1977-01-14 RO RO7789053A patent/RO71764A/en unknown
- 1977-01-15 DE DE2760284A patent/DE2760284C2/de not_active Expired - Lifetime
- 1977-01-15 DE DE19772701553 patent/DE2701553A1/en active Granted
- 1977-01-18 AU AU21419/77A patent/AU511510B2/en not_active Expired
- 1977-01-19 EG EG36/77A patent/EG12511A/en active
- 1977-01-19 NL NLAANVRAGE7700514,A patent/NL183821C/en not_active IP Right Cessation
- 1977-01-20 FR FR7701571A patent/FR2338705A1/en active Granted
- 1977-01-20 HU HU77MU577A patent/HU175973B/en unknown
- 1977-01-20 NO NO770172A patent/NO145295C/en unknown
- 1977-01-20 DK DK021677A patent/DK149804C/en not_active IP Right Cessation
- 1977-01-21 GB GB2512/77A patent/GB1575977A/en not_active Expired
- 1977-01-21 MX MX775373U patent/MX5920E/en unknown
- 1977-01-21 JP JP52006319A patent/JPS6051449B2/en not_active Expired
- 1977-01-21 GB GB9401/79A patent/GB1575978A/en not_active Expired
- 1977-01-21 DD DD7700197041A patent/DD128908A5/en unknown
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