JPS5353696A - Folic acid derivative * production thereof and radioactive analysis of folic acid salt by using said derivative - Google Patents

Folic acid derivative * production thereof and radioactive analysis of folic acid salt by using said derivative

Info

Publication number
JPS5353696A
JPS5353696A JP11780677A JP11780677A JPS5353696A JP S5353696 A JPS5353696 A JP S5353696A JP 11780677 A JP11780677 A JP 11780677A JP 11780677 A JP11780677 A JP 11780677A JP S5353696 A JPS5353696 A JP S5353696A
Authority
JP
Japan
Prior art keywords
folic acid
derivative
production
acid salt
radioactive analysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11780677A
Other languages
English (en)
Inventor
Ratonaa Haaman
Esu Akerukaa Anandorao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of JPS5353696A publication Critical patent/JPS5353696A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP11780677A 1976-09-29 1977-09-29 Folic acid derivative * production thereof and radioactive analysis of folic acid salt by using said derivative Pending JPS5353696A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/727,408 US4276280A (en) 1976-09-29 1976-09-29 Radiolabeled derivatives of folic acid

Publications (1)

Publication Number Publication Date
JPS5353696A true JPS5353696A (en) 1978-05-16

Family

ID=24922525

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11780677A Pending JPS5353696A (en) 1976-09-29 1977-09-29 Folic acid derivative * production thereof and radioactive analysis of folic acid salt by using said derivative

Country Status (10)

Country Link
US (1) US4276280A (ja)
JP (1) JPS5353696A (ja)
AU (1) AU2911077A (ja)
BE (1) BE859064A (ja)
CA (1) CA1137977A (ja)
DE (1) DE2741677A1 (ja)
FR (1) FR2366291A1 (ja)
GB (1) GB1581075A (ja)
IT (1) IT1087384B (ja)
SE (1) SE7710791L (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010523624A (ja) * 2007-04-11 2010-07-15 メルック・エプロバ・アクチエンゲゼルシヤフト １８ｆ標識葉酸

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337339A (en) 1979-04-30 1982-06-29 Baker Instruments Corp. Process for preparation of folic acid derivatives
US4298735A (en) * 1979-04-30 1981-11-03 Union Carbide Corporation Folic acid derivatives
GB2056459B (en) * 1979-07-04 1983-03-09 Daiichi Radioisotope Lab Pterin derivatives and an assay method for determining pterins
US4314988A (en) * 1979-10-31 1982-02-09 Baker Instruments Corp. Folic acid derivatives and process for preparation
EP0069450B1 (en) * 1981-06-22 1985-04-10 TECHNICON INSTRUMENTS CORPORATION (a New York corporation) Labelled vitamin b12 derivatives, their preparation and use
US5334369A (en) * 1991-06-11 1994-08-02 Medical University Of South Carolina Platelet receptor antagonists useful in detecting intravascular platelet aggregation
US5605671A (en) * 1992-10-05 1997-02-25 The Regents Of The University Of Michigan Radiolabeled neutrophil activating peptides for imaging
US5413778A (en) * 1992-10-05 1995-05-09 The Regents Of The University Of Michigan Labelled monocyte chemoattractant protein material and medical uses thereof
WO1994009128A1 (en) * 1992-10-22 1994-04-28 Mallinckrodt Medical, Inc. Therapeutic treatment for inhibiting vascular restenosis
US5800979A (en) * 1994-12-01 1998-09-01 Kolhouse; J. Fred Gas chromatography/mass spectrometric determination of folic acid coenzymes
US7192729B2 (en) 1999-07-06 2007-03-20 General Atomics Methods for assaying homocysteine
US6376210B1 (en) 1999-07-06 2002-04-23 General Atomics Methods and compositions for assaying analytes
AU2008237932C1 (en) * 2007-04-11 2014-04-24 Merck & Cie 18 F-labelled folates
CA2736861C (en) 2008-10-10 2017-11-14 Roger Schibli 18f-labelled folates as pet radiotracers
PT2776382T (pt) 2011-08-22 2018-12-24 Merck & Cie Folatos de 18f-sacárido
FR3000551B1 (fr) 2012-12-27 2015-06-26 Biomerieux Sa Derives de folate, particulierement utiles dans le cadre du dosage de folate(s)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3989812A (en) * 1974-08-09 1976-11-02 Smithkline Instruments, Inc. Folic acid derivatives and use in radio-assay
US3988431A (en) * 1974-12-12 1976-10-26 Becton, Dickinson And Company Radioassay of folates

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010523624A (ja) * 2007-04-11 2010-07-15 メルック・エプロバ・アクチエンゲゼルシヤフト １８ｆ標識葉酸

Also Published As

Publication number Publication date
BE859064A (fr) 1978-01-16
FR2366291B3 (ja) 1980-07-18
GB1581075A (en) 1980-12-10
US4276280A (en) 1981-06-30
SE7710791L (sv) 1978-03-30
FR2366291A1 (fr) 1978-04-28
AU2911077A (en) 1979-04-05
CA1137977A (en) 1982-12-21
IT1087384B (it) 1985-06-04
DE2741677A1 (de) 1978-03-30

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