JPS54138580A - Manufacture of antihistamic - Google Patents

Manufacture of antihistamic

Info

Publication number: JPS54138580A
Authority: JP; Japan
Prior art keywords: antihistamic; manufacture
Prior art date: 1978-04-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP4187679A

Other languages

English (en)

Inventor

Henrii Buraun Toomasu

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Smith Kline and French Laboratories Ltd

Original Assignee

Smith Kline and French Laboratories Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-04-11

Filing date

1979-04-05

Publication date

1979-10-27

1979-04-05 Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd

1979-10-27 Publication of JPS54138580A publication Critical patent/JPS54138580A/ja

Status Pending legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Nutrition Science (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)

JP4187679A 1978-04-11 1979-04-05 Manufacture of antihistamic Pending JPS54138580A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB1404978		1978-04-11

Publications (1)

Publication Number	Publication Date
JPS54138580A true JPS54138580A (en)	1979-10-27

Family

ID=10034068

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP4187679A Pending JPS54138580A (en)	1978-04-11	1979-04-05	Manufacture of antihistamic

Country Status (31)

Country	Link
US (1)	US4523015A (ja)
EP (1)	EP0004793B1 (ja)
JP (1)	JPS54138580A (ja)
KR (1)	KR820002136B1 (ja)
AT (1)	AT372956B (ja)
AU (1)	AU527202B2 (ja)
CA (1)	CA1138453A (ja)
CS (1)	CS210684B2 (ja)
CY (1)	CY1194A (ja)
DD (1)	DD142878A5 (ja)
DE (1)	DE2961652D1 (ja)
DK (1)	DK147379A (ja)
ES (1)	ES479469A1 (ja)
FI (1)	FI791143A7 (ja)
GR (1)	GR66986B (ja)
HU (1)	HU180081B (ja)
IE (1)	IE48080B1 (ja)
IL (1)	IL57005A (ja)
IT (1)	IT1118476B (ja)
KE (1)	KE3284A (ja)
MX (1)	MX5898E (ja)
MY (1)	MY8500703A (ja)
NO (1)	NO791225L (ja)
NZ (1)	NZ190122A (ja)
PH (2)	PH16240A (ja)
PL (2)	PL118404B1 (ja)
PT (1)	PT69464A (ja)
RO (1)	RO76810A (ja)
SU (2)	SU944504A3 (ja)
YU (1)	YU84179A (ja)
ZA (1)	ZA791616B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN151188B (ja) *	1978-02-13	1983-03-05	Smith Kline French Lab
CA1140129A (en) *	1979-08-21	1983-01-25	Ronald J. King	4-pyrimidone derivatives
CA1155842A (en) *	1980-03-29	1983-10-25	Thomas H. Brown	Compounds
US4352933A (en) *	1981-02-06	1982-10-05	Smithkline Beckman Corporation	Chemical methods and intermediates for preparing substituted pyrimidinones
PT74865B (en) *	1981-05-27	1983-12-07	Smithkline Beckman Corp	Process of preparing a 2-(pyridylbutylamino)-pyrimidone and of its pharmaceutically acceptable salts
ZA823149B (en) *	1981-05-27	1983-03-30	Smithkline Beckman Corp	Chemical process
DK230482A (da) *	1981-05-30	1982-12-01	Smith Kline French Lab	Pyrimidonsalt og fremstilling heraf
US4772704A (en) *	1983-09-21	1988-09-20	Bristol-Myers Company	2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity
IL75400A (en) *	1984-06-16	1988-10-31	Byk Gulden Lomberg Chem Fab	Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
GB8421427D0 (en) *	1984-08-23	1984-09-26	Smith Kline French Lab	Chemical compounds
DE3532880A1 (de) *	1985-09-14	1987-03-26	Basf Ag	1,4-disubstituierte pyrazolderivate
JP2807577B2 (ja) *	1990-06-15	1998-10-08	エーザイ株式会社	環状アミド誘導体
CN107698501A (zh) *	2017-10-25	2018-02-16	遵义医学院	5,6‑二甲基‑2‑羟基烟酸的制备工艺
EP4196793A1 (en)	2020-08-11	2023-06-21	Université de Strasbourg	H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5246087A (en) *	1975-10-02	1977-04-12	Smith Kline French Lab	Heterocyclic compound
JPS5283388A (en) *	1975-12-29	1977-07-12	Smith Kline French Lab	Heterocyclic compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE787372A (fr) *	1971-08-09	1973-02-09	Ici Ltd	2-nitroamino-6-hydroxy-4-methylpyrimidines substituees en position 5
GB1383676A (en) *	1972-07-14	1974-02-12	Ici Ltd	Process for making diethylamino pyrimidine derivatives
GB1419994A (en) *	1973-05-03	1976-01-07	Smith Kline French Lab	Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
US4145546A (en) *	1975-10-02	1979-03-20	Smith Kline & French Laboratories Limited	4-Pyrimidone compounds
US4154834A (en) *	1975-12-29	1979-05-15	Smith Kline & French Laboratories Limited	Substituted isocytosines having histamine H2 -antagonist activity
US4216318A (en) *	1975-12-29	1980-08-05	Smith Kline & French Laboratories Limited	Heterocyclic alkyl 4-pyrimidones
US4227000A (en) *	1978-04-11	1980-10-07	Smith Kline & French Laboratories Limited	Intermediates in the process for making histamine antagonists
PT69886A (en) *	1978-07-15	1979-08-01	Smith Kline French Lab	Process for preparing isoureas and isothioureas

1979
- 1979-04-04 PH PH22351A patent/PH16240A/en unknown
- 1979-04-04 IL IL57005A patent/IL57005A/xx unknown
- 1979-04-04 AU AU45714/79A patent/AU527202B2/en not_active Ceased
- 1979-04-05 JP JP4187679A patent/JPS54138580A/ja active Pending
- 1979-04-05 GR GR58804A patent/GR66986B/el unknown
- 1979-04-05 ZA ZA791616A patent/ZA791616B/xx unknown
- 1979-04-06 NZ NZ190122A patent/NZ190122A/xx unknown
- 1979-04-06 FI FI791143A patent/FI791143A7/fi not_active Application Discontinuation
- 1979-04-09 HU HU79SI1685A patent/HU180081B/hu unknown
- 1979-04-09 RO RO7997173A patent/RO76810A/ro unknown
- 1979-04-09 IT IT67751/79A patent/IT1118476B/it active
- 1979-04-09 CA CA000325179A patent/CA1138453A/en not_active Expired
- 1979-04-09 IE IE364/79A patent/IE48080B1/en unknown
- 1979-04-09 DK DK147379A patent/DK147379A/da not_active IP Right Cessation
- 1979-04-10 PL PL1979214792A patent/PL118404B1/pl unknown
- 1979-04-10 CS CS792440A patent/CS210684B2/cs unknown
- 1979-04-10 NO NO791225A patent/NO791225L/no unknown
- 1979-04-10 ES ES479469A patent/ES479469A1/es not_active Expired
- 1979-04-10 KR KR7901119A patent/KR820002136B1/ko not_active Expired
- 1979-04-10 MX MX797862U patent/MX5898E/es unknown
- 1979-04-10 PT PT69464A patent/PT69464A/pt unknown
- 1979-04-10 AT AT0267079A patent/AT372956B/de not_active IP Right Cessation
- 1979-04-10 PL PL1979224350A patent/PL117998B1/pl unknown
- 1979-04-10 YU YU00841/79A patent/YU84179A/xx unknown
- 1979-04-10 DD DD79212128A patent/DD142878A5/de unknown
- 1979-04-10 SU SU792747652A patent/SU944504A3/ru active
- 1979-04-11 DE DE7979300598T patent/DE2961652D1/de not_active Expired
- 1979-04-11 CY CY1194A patent/CY1194A/xx unknown
- 1979-04-11 EP EP79300598A patent/EP0004793B1/en not_active Expired
1980
- 1980-05-19 US US06/151,502 patent/US4523015A/en not_active Expired - Lifetime
- 1980-06-11 SU SU802932201A patent/SU906376A3/ru active
- 1980-06-27 PH PH24208A patent/PH16841A/en unknown
1983
- 1983-04-30 KE KE3284A patent/KE3284A/xx unknown
1985
- 1985-12-30 MY MY703/85A patent/MY8500703A/xx unknown

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5246087A (en) *	1975-10-02	1977-04-12	Smith Kline French Lab	Heterocyclic compound
JPS5283388A (en) *	1975-12-29	1977-07-12	Smith Kline French Lab	Heterocyclic compounds

Also Published As

Publication number	Publication date
KR820002136B1 (ko)	1982-11-15
GR66986B (ja)	1981-05-15
HU180081B (en)	1983-01-28
FI791143A7 (fi)	1981-01-01
YU84179A (en)	1983-04-30
US4523015A (en)	1985-06-11
PT69464A (en)	1979-05-01
KE3284A (en)	1983-05-13
PL118404B1 (en)	1981-10-31
EP0004793A3 (en)	1979-11-28
ZA791616B (en)	1980-04-30
IT7967751A0 (it)	1979-04-09
NZ190122A (en)	1982-03-09
AU527202B2 (en)	1983-02-24
IL57005A (en)	1983-11-30
AU4571479A (en)	1979-10-18
IT1118476B (it)	1986-03-03
IE48080B1 (en)	1984-09-19
DK147379A (da)	1979-10-12
CS210684B2 (en)	1982-01-29
EP0004793A2 (en)	1979-10-17
RO76810A (ro)	1981-05-30
MX5898E (es)	1984-08-22
AT372956B (de)	1983-12-12
IE790364L (en)	1979-10-11
DD142878A5 (de)	1980-07-16
SU906376A3 (ru)	1982-02-15
NO791225L (no)	1979-10-12
ES479469A1 (es)	1979-07-16
MY8500703A (en)	1985-12-31
PL117998B1 (en)	1981-09-30
ATA267079A (de)	1983-04-15
DE2961652D1 (en)	1982-02-18
CY1194A (en)	1983-12-31
EP0004793B1 (en)	1981-12-30
CA1138453A (en)	1982-12-28
PH16841A (en)	1984-03-15
PH16240A (en)	1983-08-11
PL214792A1 (ja)	1980-03-24
SU944504A3 (ru)	1982-07-15

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