JPS5461128A - Peptide derivative - Google Patents

Peptide derivative

Info

Publication number
JPS5461128A
JPS5461128A JP12469177A JP12469177A JPS5461128A JP S5461128 A JPS5461128 A JP S5461128A JP 12469177 A JP12469177 A JP 12469177A JP 12469177 A JP12469177 A JP 12469177A JP S5461128 A JPS5461128 A JP S5461128A
Authority
JP
Japan
Prior art keywords
arginine
formula
nitroanilide
peptide derivative
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12469177A
Other languages
Japanese (ja)
Other versions
JPS5919532B2 (en
Inventor
Shunpei Sakakibara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP52124691A priority Critical patent/JPS5919532B2/en
Publication of JPS5461128A publication Critical patent/JPS5461128A/en
Publication of JPS5919532B2 publication Critical patent/JPS5919532B2/en
Expired legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NEW MATERIAL:Peptide derivative of formula and its acid addition salt (R is serylglycyl, leucylglycyl, glutarylglycyl, tert-alkyloxycarbonylglycyl, valylprolyl or ter-alkyloxycarbonylprolyl).
EXAMPLE: t-Butyloxycarbonyl-glycyl-L-arginine-p-nitroanilide derivative.
USE: Useful as a synthetic substrate having specificity to enzymes such as trpsin, kallikrein, thrombin, urokinase, etc.
PROCESS: The title compound of formula is prepared e.g. by reacting L-arginine- p-nitroanilide di-hydrochloride with t-butyloxycarbonylglycine-N-hydroxysuccinimide ester in a solvent, followed by eliminating the amino- or OH-protecting groups.
COPYRIGHT: (C)1979,JPO&Japio
JP52124691A 1977-10-18 1977-10-18 peptide derivative Expired JPS5919532B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP52124691A JPS5919532B2 (en) 1977-10-18 1977-10-18 peptide derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52124691A JPS5919532B2 (en) 1977-10-18 1977-10-18 peptide derivative

Publications (2)

Publication Number Publication Date
JPS5461128A true JPS5461128A (en) 1979-05-17
JPS5919532B2 JPS5919532B2 (en) 1984-05-07

Family

ID=14891695

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52124691A Expired JPS5919532B2 (en) 1977-10-18 1977-10-18 peptide derivative

Country Status (1)

Country Link
JP (1) JPS5919532B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6061557A (en) * 1983-09-14 1985-04-09 Nitto Boseki Co Ltd Production of arginyl-p-nitroanilide

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5397229B2 (en) 2008-02-22 2014-01-22 和光純薬工業株式会社 Substrate for measuring β-glucan and / or endotoxin and measuring method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6061557A (en) * 1983-09-14 1985-04-09 Nitto Boseki Co Ltd Production of arginyl-p-nitroanilide

Also Published As

Publication number Publication date
JPS5919532B2 (en) 1984-05-07

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