JPS5481264A - Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid - Google Patents

Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid

Info

Publication number
JPS5481264A
JPS5481264A JP14658277A JP14658277A JPS5481264A JP S5481264 A JPS5481264 A JP S5481264A JP 14658277 A JP14658277 A JP 14658277A JP 14658277 A JP14658277 A JP 14658277A JP S5481264 A JPS5481264 A JP S5481264A
Authority
JP
Japan
Prior art keywords
formula
acetic acid
methylpyrrole
methyl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14658277A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5516579B2 (de
Inventor
Sei Kondo
Minoru Suda
Daiei Tsunemoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Priority to JP14658277A priority Critical patent/JPS5481264A/ja
Priority to SE7811704A priority patent/SE435278B/sv
Priority to US05/963,673 priority patent/US4238396A/en
Priority to GB7847086A priority patent/GB2014131B/en
Priority to PH21894A priority patent/PH15394A/en
Priority to CA000317552A priority patent/CA1121364A/en
Priority to LU80620A priority patent/LU80620A1/de
Priority to ES475807A priority patent/ES475807A1/es
Priority to AT0878478A priority patent/AT372372B/de
Priority to FI783768A priority patent/FI66848C/fi
Priority to FR7834471A priority patent/FR2411180A1/fr
Priority to CH1248078A priority patent/CH644103A5/de
Priority to NL7811940A priority patent/NL7811940A/xx
Priority to IT52240/78A priority patent/IT1157750B/it
Priority to AU42313/78A priority patent/AU529229B2/en
Priority to DK553378A priority patent/DK553378A/da
Priority to IE2419/78A priority patent/IE47793B1/en
Priority to DE2852975A priority patent/DE2852975C2/de
Priority to PCT/JP1978/000042 priority patent/WO1979000357A1/ja
Priority to FR7909463A priority patent/FR2414040A1/fr
Publication of JPS5481264A publication Critical patent/JPS5481264A/ja
Priority to PH23259A priority patent/PH17068A/en
Publication of JPS5516579B2 publication Critical patent/JPS5516579B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP14658277A 1977-12-08 1977-12-08 Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid Granted JPS5481264A (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
JP14658277A JPS5481264A (en) 1977-12-08 1977-12-08 Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid
SE7811704A SE435278B (sv) 1977-12-08 1978-11-13 5-cyano-1-legre(c?711?71-?714)alkyl-pyrrol-2-ettiksyra, framstellning derav och anvendningen som mellanprodukt vid framstellning av terapeutiskt verksamma pyrrolderivat
US05/963,673 US4238396A (en) 1977-12-08 1978-11-27 1-Hydrocarbyl-pyrrole-2-acetic acid derivatives and their production
GB7847086A GB2014131B (en) 1977-12-08 1978-12-04 1-hydrocarbylpyrrole derivatives
PH21894A PH15394A (en) 1977-12-08 1978-12-06 Production of 1 hydrocarbyl pyrrole-2-acetic acids derivatives
CH1248078A CH644103A5 (de) 1977-12-08 1978-12-07 In 1-stellung durch einen kohlenwasserstoffrest substituierte 5-cyano-pyrrolyl-essigsaeuren, ihre herstellung und verwendung zur herstellung entsprechender 5-acyl-verbindungen.
AU42313/78A AU529229B2 (en) 1977-12-08 1978-12-07 1-hydrocarbylpyrrole derivatives x
ES475807A ES475807A1 (es) 1977-12-08 1978-12-07 Un procedimiento para preparar acidos 5-acil-1-hidrocarbil- pirrol-2-acetico.
AT0878478A AT372372B (de) 1977-12-08 1978-12-07 Verfahren zur herstellung von 5-acyl-1nideralkylpyrrol-2-essigsaeuren
FI783768A FI66848C (fi) 1977-12-08 1978-12-07 Foerfarande foer framstaellning av 1-alkylpyrrol-2-aettiksyraderivat den i foerfarandet anvaenda mellanprodukten och dess framstaellning
FR7834471A FR2411180A1 (fr) 1977-12-08 1978-12-07 Procede de preparation de 1-hydrocarbyl-2-(2',2',2'-trihalogeno-1'-hydroxyethyl)pyrroles
CA000317552A CA1121364A (en) 1977-12-08 1978-12-07 1-hydrocarbylpyrrole-2-acetic acid derivatives and their production
NL7811940A NL7811940A (nl) 1977-12-08 1978-12-07 Werkwijze ter bereiding van 1-hydrocarbylpyrrool-2-azijnzuurderivaten.
IT52240/78A IT1157750B (it) 1977-12-08 1978-12-07 Procedimento per la preparazione di derivati di acido 1-idrocarbilpirrolo-2-acetico e prodotto ottenuto
LU80620A LU80620A1 (de) 1977-12-08 1978-12-07 1-hydrocarbylpyrrol-2-essigsaeure-derivate und verfahren zu ihrer herstellung
DK553378A DK553378A (da) 1977-12-08 1978-12-07 Fremgangsmaade til fremstilling af 1-hydrocarbylpyrrol-2-eddikesyrederivater
IE2419/78A IE47793B1 (en) 1977-12-08 1978-12-07 1-hydrocarbylpyrrole derivatives
DE2852975A DE2852975C2 (de) 1977-12-08 1978-12-07 5-Cyano-1-alkylpyrrol-2-essigsäure-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
PCT/JP1978/000042 WO1979000357A1 (fr) 1977-12-08 1978-12-08 Procede de preparation d'acide 1-methyl-5-acroylpyrol-2 acetique
FR7909463A FR2414040A1 (fr) 1977-12-08 1979-04-13 Acides 5-cyano-1-hydrocarbylpyrrole-2-acetiques leur preparation et leur application a la production d'acides 5-acyles correspondants
PH23259A PH17068A (en) 1977-12-08 1979-11-08 5-cyano-1-methylpyrrole 2-acetic acid and process of preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14658277A JPS5481264A (en) 1977-12-08 1977-12-08 Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid

Publications (2)

Publication Number Publication Date
JPS5481264A true JPS5481264A (en) 1979-06-28
JPS5516579B2 JPS5516579B2 (de) 1980-05-02

Family

ID=15410949

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14658277A Granted JPS5481264A (en) 1977-12-08 1977-12-08 Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid

Country Status (3)

Country Link
JP (1) JPS5481264A (de)
AT (1) AT372372B (de)
WO (1) WO1979000357A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60104871U (ja) * 1983-12-21 1985-07-17 株式会社　林物産 横断旗

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4830635A (de) * 1971-08-25 1973-04-23

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791500A (fr) * 1971-11-19 1973-05-17 Hoffmann La Roche Procede pour la preparation de 2-(2-aminobenzoyl) pyridines
JPS5128601B2 (de) * 1972-04-18 1976-08-20
US3846447A (en) * 1972-08-03 1974-11-05 Mcneilab Inc Preparation of 5-aroyl-pyrroles and intermediates therefor
US3998844A (en) * 1975-06-02 1976-12-27 Mcneil Laboratories, Incorporated Uncatalyzed aroylation of 1-alkylpyrrole-2-acetic acid derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4830635A (de) * 1971-08-25 1973-04-23

Also Published As

Publication number Publication date
AT372372B (de) 1983-09-26
WO1979000357A1 (fr) 1979-06-28
ATA878478A (de) 1983-02-15
JPS5516579B2 (de) 1980-05-02

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