JPS55100380A - 11imidazoll22ylidenee33heterocyclic urea derivative*its manufacture and pharmaceutic composition having antidepressive activity - Google Patents
11imidazoll22ylidenee33heterocyclic urea derivative*its manufacture and pharmaceutic composition having antidepressive activityInfo
- Publication number
- JPS55100380A JPS55100380A JP375680A JP375680A JPS55100380A JP S55100380 A JPS55100380 A JP S55100380A JP 375680 A JP375680 A JP 375680A JP 375680 A JP375680 A JP 375680A JP S55100380 A JPS55100380 A JP S55100380A
- Authority
- JP
- Japan
- Prior art keywords
- manufacture
- compounds
- urea derivative
- pharmaceutic composition
- antidepressive activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 230000001430 anti-depressive effect Effects 0.000 title 1
- 239000004202 carbamide Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000009858 acid secretion Effects 0.000 abstract 1
- 230000000949 anxiolytic effect Effects 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/004,675 US4230713A (en) | 1979-01-19 | 1979-01-19 | Heterocyclic tetrahydro-1-alkyl-4-oxo-1H-imidazol-2-ylidene urea and phenyl esters of tetrahydro-1-alkyl-4-oxo-1H-imidazol-2-ylidene carbamic acid compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS55100380A true JPS55100380A (en) | 1980-07-31 |
Family
ID=21711951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP375680A Pending JPS55100380A (en) | 1979-01-19 | 1980-01-18 | 11imidazoll22ylidenee33heterocyclic urea derivative*its manufacture and pharmaceutic composition having antidepressive activity |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4230713A (ja) |
| EP (1) | EP0013817B1 (ja) |
| JP (1) | JPS55100380A (ja) |
| AT (1) | ATE3769T1 (ja) |
| CA (1) | CA1122600A (ja) |
| DE (1) | DE2965701D1 (ja) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4472583A (en) * | 1980-02-05 | 1984-09-18 | The Dow Chemical Company | 4-Isothiocyanato-2,6-bis-(trifluoromethyl)pyridine |
| DE3674054D1 (de) * | 1985-04-26 | 1990-10-18 | Hoffmann La Roche | 1,3-disubstituierte imidazoliumsalze. |
| US4657922A (en) * | 1985-05-24 | 1987-04-14 | Mcneilab, Inc. | Anxiolytic 4,5-dihydro-4-oxo-1H-imidazol-2-yl urea derivatives |
| WO1999005194A1 (de) | 1997-07-22 | 1999-02-04 | Basf Coatings Ag | Beschichtungsmittel und verfahren zu dessen herstellung |
| US20030220646A1 (en) * | 2002-05-23 | 2003-11-27 | Thelen Sarah L. | Method and apparatus for reducing femoral fractures |
| AU2006327300A1 (en) * | 2005-12-20 | 2007-06-28 | Astrazeneca Ab | Substituted Cinnoline derivatives as GABAa-receptor modulators and method for their synthesis |
| US7465795B2 (en) * | 2005-12-20 | 2008-12-16 | Astrazeneca Ab | Compounds and uses thereof |
| AR067028A1 (es) * | 2007-06-19 | 2009-09-30 | Astrazeneca Ab | Compuestos y usos de los mismos 849 |
| US20210236466A1 (en) * | 2018-07-03 | 2021-08-05 | Ifm Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3983135A (en) * | 1974-09-23 | 1976-09-28 | Mcneil Laboratories, Incorporated | 4-Oxo-2-imidazolidinylidene ureas |
-
1979
- 1979-01-19 US US06/004,675 patent/US4230713A/en not_active Expired - Lifetime
- 1979-12-07 CA CA341,498A patent/CA1122600A/en not_active Expired
- 1979-12-17 DE DE7979302921T patent/DE2965701D1/de not_active Expired
- 1979-12-17 AT AT79302921T patent/ATE3769T1/de not_active IP Right Cessation
- 1979-12-17 EP EP79302921A patent/EP0013817B1/en not_active Expired
-
1980
- 1980-01-18 JP JP375680A patent/JPS55100380A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE2965701D1 (en) | 1983-07-21 |
| EP0013817B1 (en) | 1983-06-15 |
| EP0013817A1 (en) | 1980-08-06 |
| CA1122600A (en) | 1982-04-27 |
| ATE3769T1 (de) | 1983-06-15 |
| US4230713A (en) | 1980-10-28 |
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