JPS5515476B1 - - Google Patents

Info

Publication number
JPS5515476B1
JPS5515476B1 JP7194A JP9471A JPS5515476B1 JP S5515476 B1 JPS5515476 B1 JP S5515476B1 JP 7194 A JP7194 A JP 7194A JP 9471 A JP9471 A JP 9471A JP S5515476 B1 JPS5515476 B1 JP S5515476B1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7194A
Other languages
Japanese (ja)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS5515476B1 publication Critical patent/JPS5515476B1/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP7194A 1970-01-06 1971-01-06 Pending JPS5515476B1 (2)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
JPS5515476B1 true JPS5515476B1 (2) 1980-04-23

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7194A Pending JPS5515476B1 (2) 1970-01-06 1971-01-06

Country Status (19)

Country Link
JP (1) JPS5515476B1 (2)
AT (1) AT303041B (2)
BE (1) BE761219A (2)
CA (1) CA999866A (2)
CH (2) CH538477A (2)
DE (1) DE2062001C2 (2)
DK (1) DK125021B (2)
ES (1) ES387016A1 (2)
FI (1) FI49503C (2)
FR (1) FR2081412B1 (2)
GB (1) GB1335261A (2)
IE (1) IE34859B1 (2)
IL (1) IL35916A (2)
NL (1) NL171444C (2)
NO (1) NO135315C (2)
PH (1) PH9682A (2)
SE (3) SE386672B (2)
YU (1) YU33660B (2)
ZA (1) ZA708590B (2)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003513074A (ja) * 1999-11-03 2003-04-08 アルバニー モレキュラー リサーチ インコーポレーティッド アリールおよびヘテロアリール置換テトラヒドロイソキノリン、ならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを阻止するためのそれらの使用
JP2004501860A (ja) * 1999-11-03 2004-01-22 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー ノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するための、４−フェニル置換テトラヒドロイソキノリン類およびその利用

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
EP1113007A1 (en) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
KR100821410B1 (ko) 2000-07-11 2008-04-10 에이엠알 테크놀로지, 인크. 4-페닐 치환된 테트라하이드로이소퀴놀린 및 이의치료학적 용도
UA91341C2 (ru) 2004-07-15 2010-07-26 Амр Текнолоджи, Інк. Арил- и гетероарилзамещенные тетрагидроизохинолины и их применение для блокирования обратного захвата норэпинефрина, допамина и серотонина
WO2006138714A2 (en) * 2005-06-17 2006-12-28 Janssen Pharmaceutica N.V. Naphthyridine compounds
UA95454C2 (uk) 2005-07-15 2011-08-10 Амр Текнолоджи, Інк. Арил- і гетероарилзаміщені тетрагідробензазепіни і їх застосування для блокування зворотного захоплення норепінефрину, допаміну і серотоніну
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
EP2429295B1 (en) 2009-05-12 2013-12-25 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
AU2010247763B2 (en) 2009-05-12 2015-12-24 Albany Molecular Research, Inc. 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
US8815894B2 (en) 2009-05-12 2014-08-26 Bristol-Myers Squibb Company Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003513074A (ja) * 1999-11-03 2003-04-08 アルバニー モレキュラー リサーチ インコーポレーティッド アリールおよびヘテロアリール置換テトラヒドロイソキノリン、ならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを阻止するためのそれらの使用
JP2004501860A (ja) * 1999-11-03 2004-01-22 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー ノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するための、４−フェニル置換テトラヒドロイソキノリン類およびその利用

Also Published As

Publication number Publication date
FI49503B (2) 1975-04-01
FR2081412A1 (2) 1971-12-03
NL171444B (nl) 1982-11-01
SE399879B (sv) 1978-03-06
AT303041B (de) 1972-11-10
DK125021B (da) 1972-12-18
IE34859L (en) 1971-07-06
CA999866A (en) 1976-11-16
CH527194A (de) 1972-08-31
YU1971A (en) 1977-06-30
PH9682A (en) 1976-02-10
ES387016A1 (es) 1976-05-01
CH538477A (de) 1973-06-30
NL171444C (nl) 1983-04-05
BE761219A (fr) 1971-07-05
NO135315C (2) 1977-03-23
NO135315B (2) 1976-12-13
IL35916A0 (en) 1971-02-25
GB1335261A (en) 1973-10-24
SE386672B (sv) 1976-08-16
SE368401B (2) 1974-07-01
FR2081412B1 (2) 1974-04-12
NL7018956A (2) 1971-07-08
DE2062001A1 (de) 1971-07-15
IE34859B1 (en) 1975-09-03
IL35916A (en) 1973-11-28
DE2062001C2 (de) 1986-10-16
FI49503C (fi) 1975-07-10
YU33660B (en) 1977-12-31
ZA708590B (en) 1971-09-29

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