JPS55164643A - Purification of coenzyme q - Google Patents

Purification of coenzyme q

Info

Publication number
JPS55164643A
JPS55164643A JP7386579A JP7386579A JPS55164643A JP S55164643 A JPS55164643 A JP S55164643A JP 7386579 A JP7386579 A JP 7386579A JP 7386579 A JP7386579 A JP 7386579A JP S55164643 A JPS55164643 A JP S55164643A
Authority
JP
Japan
Prior art keywords
isopropanol
coenzyme
give
mixture
high purity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7386579A
Other languages
Japanese (ja)
Inventor
Hirokazu Ryono
Fusayoshi Kakizaki
Hirozumi Etou
Arahiko Eguchi
Masao Nakamura
Takao Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP7386579A priority Critical patent/JPS55164643A/en
Publication of JPS55164643A publication Critical patent/JPS55164643A/en
Pending legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To obtain a high purity coenzyme Q, which takes an important role in the biological electron transport system and has an excellent pharmaceutical activity for various diseases, at room temp., easily, in the yield, by recrystallizing a low purity coenzyme Q using isopropanol as a solvent.
CONSTITUTION: A coenzyme Q having 40W98% purity is recrystallized in isopropanol by conventional method to give the high purity coenzyme. For example, the starting material is dissolved in isopropanol by heating at 35W60°C to give a homogeneous solution, which is then cooled to ca. 0W35°C. The recrystallization solvent may be a mixture of isopropanol and an organic solvent soluble in isopropanol, e.g. hexane, ethyl ether, acetone, etc. In this case the amount of isopropanol is preferably 50W99% (V/V). Esp. a mixture of isopropanol and 5W30% of ethyl acetate is preferable for removing a trace of impurities.
COPYRIGHT: (C)1980,JPO&Japio
JP7386579A 1979-06-12 1979-06-12 Purification of coenzyme q Pending JPS55164643A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7386579A JPS55164643A (en) 1979-06-12 1979-06-12 Purification of coenzyme q

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7386579A JPS55164643A (en) 1979-06-12 1979-06-12 Purification of coenzyme q

Publications (1)

Publication Number Publication Date
JPS55164643A true JPS55164643A (en) 1980-12-22

Family

ID=13530489

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7386579A Pending JPS55164643A (en) 1979-06-12 1979-06-12 Purification of coenzyme q

Country Status (1)

Country Link
JP (1) JPS55164643A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53127891A (en) * 1977-04-12 1978-11-08 Nisshin Flour Milling Co Ltd Crystallization of co-enzyme q

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53127891A (en) * 1977-04-12 1978-11-08 Nisshin Flour Milling Co Ltd Crystallization of co-enzyme q

Similar Documents

Publication Publication Date Title
JPS5331639A (en) Preparation of benzyl benzoate
JPS5283428A (en) Preparation of aromatic carboxylic acid amide derivatives
JPS53130623A (en) Preparation of n-hydroxyalkyl-substituted phosphoroamidate
JPS53127891A (en) Crystallization of co-enzyme q
JPS5262234A (en) Process for preparation of n_3'-hydroxyphenyl-2-methylbenzamide
JPS5212146A (en) Process for preparation of p- acetylaminobenzene-sufonylchloride
JPS5422363A (en) Preparation of thiophene-substituted fatty acid halide
JPS5257142A (en) Process for preparing dihalovinyl-cyclopropanecarboxylic acid derivati ves
JPS53130619A (en) Preparation of high purity isoprenylacetic acid
JPS52106857A (en) Preparation of 1,3-disubstituted-2-azetidinones
JPS51113882A (en) Method for preparing 1-(alpha -alkoxyalkyl)-uracil derivatives
JPS5266531A (en) Preparation of oxazolylethylene compounds
JPS5246013A (en) Process for preparation of gamma-unsaturated carboxylic acid esters
JPS5271500A (en) Purification of colesterol
JPS539715A (en) Crystallization of dl-acetylmethionine
JPS5239648A (en) Aprocess for preparing p-cyanobenzoic acid amide from terephthalonitril e
JPS5246014A (en) Process for preparation of gamma-unsaturated carboxylic acid esters
JPS5236654A (en) Process for preparation of steroid derivatives
JPS5262291A (en) Preparation of 7-aamino-deacetoxycephalosporanic acid derivatives
JPS53144562A (en) Preparation of steroid derivatives
JPS53144563A (en) Preparation of steroid derivatives
JPS51113873A (en) Method for synthesizing 4-oxo-4h-thiopyran derivatives
JPS5646872A (en) Purification of 2,2'-bis(2-oxazoline)
JPS5283412A (en) Preparation of 3,3-dimethyl-4-pentenoic acids
JPS5395985A (en) Preparation of aminopyrazinecarboxylic acid