JPS5520747A - Antidepressant - Google Patents

Antidepressant

Info

Publication number
JPS5520747A
JPS5520747A JP9428778A JP9428778A JPS5520747A JP S5520747 A JPS5520747 A JP S5520747A JP 9428778 A JP9428778 A JP 9428778A JP 9428778 A JP9428778 A JP 9428778A JP S5520747 A JPS5520747 A JP S5520747A
Authority
JP
Japan
Prior art keywords
dops
antidepressant
threo
erythro
dihydroxyphenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9428778A
Other languages
Japanese (ja)
Inventor
Takemoto Honma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP9428778A priority Critical patent/JPS5520747A/en
Publication of JPS5520747A publication Critical patent/JPS5520747A/en
Pending legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: An antidepressant containing 3-(3,4-dihydroxyphenyl)-serine as the effective ingredient that has different action mechanism from tricycle antidepressant.
CONSTITUTION: Said antidepressant contains 3-(3,4-dihydroxyphenyl)-serine or its salt (DOPS) as the effective ingredient. DOPS has four optical isomers of L-threo- DOPS, D-threo-DOPS, L-erythro-DOPS and D-erythro-DOPS, of which L-threo- DOPS is the most effective. DOPS inhibits the hypothermy of mouse caused by reserpine and tetrabenazine, thus showing antidepressant activity.
COPYRIGHT: (C)1980,JPO&Japio
JP9428778A 1978-08-01 1978-08-01 Antidepressant Pending JPS5520747A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9428778A JPS5520747A (en) 1978-08-01 1978-08-01 Antidepressant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9428778A JPS5520747A (en) 1978-08-01 1978-08-01 Antidepressant

Publications (1)

Publication Number Publication Date
JPS5520747A true JPS5520747A (en) 1980-02-14

Family

ID=14106035

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9428778A Pending JPS5520747A (en) 1978-08-01 1978-08-01 Antidepressant

Country Status (1)

Country Link
JP (1) JPS5520747A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6067420A (en) * 1983-09-22 1985-04-17 Sumitomo Chem Co Ltd Agent for suppressing psychokinetic excitation
WO1999052519A3 (en) * 1998-04-14 1999-12-02 Gen Hospital Corp Methods for treating neuropsychiatric disorders

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5049252A (en) * 1973-08-22 1975-05-01

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5049252A (en) * 1973-08-22 1975-05-01

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6067420A (en) * 1983-09-22 1985-04-17 Sumitomo Chem Co Ltd Agent for suppressing psychokinetic excitation
WO1999052519A3 (en) * 1998-04-14 1999-12-02 Gen Hospital Corp Methods for treating neuropsychiatric disorders
US6228875B1 (en) 1998-04-14 2001-05-08 The General Hospital Corporation Methods for treating neuropsychiatric disorders
US6667297B2 (en) 1998-04-14 2003-12-23 The General Hospital Corporation Methods for treating neuropsychiatric disorders
US6974821B2 (en) 1998-04-14 2005-12-13 The General Hospital Corporation Methods for treating neuropsychiatric disorders
US7704978B2 (en) 1998-04-14 2010-04-27 The General Hospital Corporation Methods for treating neuropsychiatric disorders

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