JPS552631A - 3,4-dihydrocarbostyril derivative - Google Patents

3,4-dihydrocarbostyril derivative

Info

Publication number
JPS552631A
JPS552631A JP7477278A JP7477278A JPS552631A JP S552631 A JPS552631 A JP S552631A JP 7477278 A JP7477278 A JP 7477278A JP 7477278 A JP7477278 A JP 7477278A JP S552631 A JPS552631 A JP S552631A
Authority
JP
Japan
Prior art keywords
formula
group
benzyl
dihydrocarbostyril
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7477278A
Other languages
Japanese (ja)
Other versions
JPS6126909B2 (en
Inventor
Michiaki Tominaga
Hitoshi Tone
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP7477278A priority Critical patent/JPS552631A/en
Publication of JPS552631A publication Critical patent/JPS552631A/en
Publication of JPS6126909B2 publication Critical patent/JPS6126909B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

MEW MATERIAL:A 3,4-dihydrocarbostyril derivative of formula I: [R<1> is H, benzyloxycarbonyl, 2-tetrahydropyranyl, R<3> CO(CH2)m-(R<3> is lower alkyl group; m is an integer 1-4), or group of formula II; R<2> is H, benzyl, benzyloxycarbonyl group) R<1> is not H or R<3> CO(CH2)m-when R<2> is H or benzyl group], and its acid addition salt. EXAMPLE:8-(2-Tetrahydropyranyloxy)-5-[3-(N-benzyl-beta-3,4-dimethoxyph enethylamino)-2-hydroxypropoxy]-3,4-dihydrocarbostyril. USE:Remedies or their intermediates for angina pectoris, arrhythmia, and hypertension, e.g. blocking agents having selectivity to heart. PROCESS:A carbostyril derivative of formula III is reacted with an amine of formula IV to give the objective compound of formula I.
JP7477278A 1978-06-19 1978-06-19 3,4-dihydrocarbostyril derivative Granted JPS552631A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7477278A JPS552631A (en) 1978-06-19 1978-06-19 3,4-dihydrocarbostyril derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7477278A JPS552631A (en) 1978-06-19 1978-06-19 3,4-dihydrocarbostyril derivative

Publications (2)

Publication Number Publication Date
JPS552631A true JPS552631A (en) 1980-01-10
JPS6126909B2 JPS6126909B2 (en) 1986-06-23

Family

ID=13556905

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7477278A Granted JPS552631A (en) 1978-06-19 1978-06-19 3,4-dihydrocarbostyril derivative

Country Status (1)

Country Link
JP (1) JPS552631A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309432A (en) * 1979-01-30 1982-01-05 Otsuka Pharmaceutical Company, Ltd. Compositions for treating glaucoma containing a carbostyril

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309432A (en) * 1979-01-30 1982-01-05 Otsuka Pharmaceutical Company, Ltd. Compositions for treating glaucoma containing a carbostyril

Also Published As

Publication number Publication date
JPS6126909B2 (en) 1986-06-23

Similar Documents

Publication Publication Date Title
EP0283970A3 (en) New peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same
JPS54130587A (en) Carbostyryl derivative
PL238012A1 (en) Process for preparing 2-/2&#39; - hydroxy-3&#39;-/1,2-dimethyl-propylamino/-propoxy/-beta-phenylpropiophenone
US4154849A (en) N-Cyano-2-(substituted phenoxy) butyramides and their use as mildewicides
IE792329L (en) Thiazaheterocyclics and process for preparing pyrrolidine¹and piperidine derivatives.
US4168319A (en) N-alkynyl-2-(substituted phenoxy) butyramides and their use as mildewicides
JPS552631A (en) 3,4-dihydrocarbostyril derivative
DE2963729D1 (en) New intermediates and their use for the preparation of new oxadiazolo-pyrimidine derivatives
JPS55127371A (en) Carbostyril derivative
NO138808C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE PREGNANIC ACID DERIVATIVES
JPS5649364A (en) Carbostyril derivative
FR2359150A1 (en) TIN-TRIORGANIC DERIVATIVES OF HYDROXYDIAZENIUM OXIDES FOR USE AS FUNGICIDES
FR2427326A2 (en) NEW POLYIODIC IONIC DERIVATIVES OF BENZENE, USABLE AS OPACIFYING PRODUCTS FOR RADIOGRAPHY
GB1505020A (en) Substituted 2-phenylimino-thiazolines a process for their preparation and their use as ectoparasiticides
FR2433536A1 (en) NEW ANDROST 4-ENE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS A MEDICAMENT
FR2446835A1 (en) OCTAHYDRO-2H-PYRROLO (3,4-G) QUINOLEINS USEFUL AS INTERMEDIATES
FR2442236A1 (en)
FR2444047A1 (en) NOVEL 2,2-DIMETHYL 19-NOR STEROIDS DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
JPS5697266A (en) Proline derivative and its preparation
JPS5780321A (en) Cardiotonic agent
JPS54128583A (en) Thiosemicarbazone derivative
JPS552655A (en) Quinoline derivative
GB758382A (en) Improvements in bis-(ú­-aminophenoxy) alkane derivatives
FR2362827A1 (en) NEW DIURETHANES USEFUL AS HERBICIDES
JPS5649357A (en) Quinoline derivative