JPS5571702A - Antitumorous glucan derivative, its preparation, and carcinostatic substance containing it - Google Patents

Antitumorous glucan derivative, its preparation, and carcinostatic substance containing it

Info

Publication number
JPS5571702A
JPS5571702A JP14517678A JP14517678A JPS5571702A JP S5571702 A JPS5571702 A JP S5571702A JP 14517678 A JP14517678 A JP 14517678A JP 14517678 A JP14517678 A JP 14517678A JP S5571702 A JPS5571702 A JP S5571702A
Authority
JP
Japan
Prior art keywords
glucan
derivative
decomposition
glucan derivative
corticiaceae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14517678A
Other languages
Japanese (ja)
Inventor
Eiji Oki
Hiromichi Saeki
Kenkichi Shinkai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP14517678A priority Critical patent/JPS5571702A/en
Publication of JPS5571702A publication Critical patent/JPS5571702A/en
Pending legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

PURPOSE: To obtain a glucan derivative and its boric acid inclusion compound useful for a carcinostatic substance, easily soluble in water and capable of making an aqueous solution scarcely being gelled by Smith decomposition of neutral polysaccharide produced by a basidiomycete of corticiaceae.
CONSTITUTION: A neutral polysaccharide produced by a basidiomycete of corticiaceae, for example, cortican as a starting material, undergoes Smith decomposition which is utilized in the decomposition of polysaccharide, preferably is treated with sodium periodate and reduced by sodium boron hydride to give a glucan derivative and its boric acid inclusion compound. The glucon derivative has a straight chain (1→3)β-D-glucan as a basic skeleton, wherein hydroxyl groups at 6 six position are replaced by 2-hydroxy-1-(1,3-dihydroxyprop-2-yloxy)ethyl group as substituent groups in a proportion of 2 per 6W7 of the constituent glucose.
COPYRIGHT: (C)1980,JPO&Japio
JP14517678A 1978-11-24 1978-11-24 Antitumorous glucan derivative, its preparation, and carcinostatic substance containing it Pending JPS5571702A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14517678A JPS5571702A (en) 1978-11-24 1978-11-24 Antitumorous glucan derivative, its preparation, and carcinostatic substance containing it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14517678A JPS5571702A (en) 1978-11-24 1978-11-24 Antitumorous glucan derivative, its preparation, and carcinostatic substance containing it

Publications (1)

Publication Number Publication Date
JPS5571702A true JPS5571702A (en) 1980-05-30

Family

ID=15379182

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14517678A Pending JPS5571702A (en) 1978-11-24 1978-11-24 Antitumorous glucan derivative, its preparation, and carcinostatic substance containing it

Country Status (1)

Country Link
JP (1) JPS5571702A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5634701A (en) * 1979-08-29 1981-04-07 Meito Sangyo Kk Beta-1,3-glucan, its preparation and use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5634701A (en) * 1979-08-29 1981-04-07 Meito Sangyo Kk Beta-1,3-glucan, its preparation and use

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