JPS5585571A - Preparation of 1,3-disubstituted-5-pyrazolone - Google Patents
Preparation of 1,3-disubstituted-5-pyrazoloneInfo
- Publication number
- JPS5585571A JPS5585571A JP16061978A JP16061978A JPS5585571A JP S5585571 A JPS5585571 A JP S5585571A JP 16061978 A JP16061978 A JP 16061978A JP 16061978 A JP16061978 A JP 16061978A JP S5585571 A JPS5585571 A JP S5585571A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- solvent
- compound
- pyrazolone
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 1,3-disubstituted-5-pyrazolone Chemical class 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 239000002904 solvent Substances 0.000 abstract 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 abstract 2
- NDELSWXIAJLWOU-UHFFFAOYSA-N 2,5-dimethyl-4h-pyrazol-3-one Chemical compound CN1N=C(C)CC1=O NDELSWXIAJLWOU-UHFFFAOYSA-N 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 230000002363 herbicidal effect Effects 0.000 abstract 1
- 239000004009 herbicide Substances 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
Abstract
PURPOSE: To obtain the title compound (especially a 1,3-dimethyl substituted compound useful an an intermediate for a herbicide) from a low-priced raw material in relatively short time in high yield, by reacting 3-substituted-5-pyrazolone with a chlorinated alkyl in a solvent, e.g., DMF, etc.
CONSTITUTION: A compound shown by the formula I (R is alkyl) is reacted with a chlorinated alkyl shown by the formula R'Cl (R' is lower alkyl) in a solvent, e.g., DMF, etc. to give the desired compound (especially 1,3-dimethyl-5-pyrazolone) shown by the formula II. The selection of a solvent is important in the reaction, and the use of methyl alcohol, ethyl alcohol, propyl alcohol, isopropyl alcohol, etc. besides DMF raise the yield. An amount of the chlorinated alkyl is 2 moles or more based on 1 mole of the compound shown by the formula I and an amount of the solvent is 30W100ml based on the compound shown by the formula I. The reaction undergoes at 60W120°C for 5W10 hours.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16061978A JPS5585571A (en) | 1978-12-22 | 1978-12-22 | Preparation of 1,3-disubstituted-5-pyrazolone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16061978A JPS5585571A (en) | 1978-12-22 | 1978-12-22 | Preparation of 1,3-disubstituted-5-pyrazolone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5585571A true JPS5585571A (en) | 1980-06-27 |
| JPS6221781B2 JPS6221781B2 (en) | 1987-05-14 |
Family
ID=15718841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16061978A Granted JPS5585571A (en) | 1978-12-22 | 1978-12-22 | Preparation of 1,3-disubstituted-5-pyrazolone |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5585571A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4936233A (en) * | 1972-07-29 | 1974-04-04 | ||
| JPS5012082A (en) * | 1973-04-17 | 1975-02-07 |
-
1978
- 1978-12-22 JP JP16061978A patent/JPS5585571A/en active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4936233A (en) * | 1972-07-29 | 1974-04-04 | ||
| JPS5012082A (en) * | 1973-04-17 | 1975-02-07 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6221781B2 (en) | 1987-05-14 |
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