JPS5587715A - Stabilization of bacanpicillin hydrochloride - Google Patents

Stabilization of bacanpicillin hydrochloride

Info

Publication number
JPS5587715A
JPS5587715A JP16183078A JP16183078A JPS5587715A JP S5587715 A JPS5587715 A JP S5587715A JP 16183078 A JP16183078 A JP 16183078A JP 16183078 A JP16183078 A JP 16183078A JP S5587715 A JPS5587715 A JP S5587715A
Authority
JP
Japan
Prior art keywords
bapc
bacanpicillin
hydrochloride
heating
necessary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16183078A
Other languages
Japanese (ja)
Other versions
JPS5713529B2 (en
Inventor
Tomohiro Hayashida
Naohiro Oishi
Masaki Sasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Yoshitomi Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoshitomi Pharmaceutical Industries Ltd filed Critical Yoshitomi Pharmaceutical Industries Ltd
Priority to JP16183078A priority Critical patent/JPS5587715A/en
Publication of JPS5587715A publication Critical patent/JPS5587715A/en
Publication of JPS5713529B2 publication Critical patent/JPS5713529B2/ja
Granted legal-status Critical Current

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  • Medicinal Preparation (AREA)

Abstract

PURPOSE: To stabilize and improve the moisture resistance of the title compound useful as an orally administrable penicillin, by mixing bacanpicillin hydrochloride with a specific additive homogeneously, and if necessary, heating the mixture.
CONSTITUTION: Bacanpicillin hydrochloride (BAPC) is stabilized by mixing homogeneously with at least one material selected from oils, fats, fatty acids, their esters, higher alcohols, waxes and paraffins, and if necessary, heating the mixture pref. at 40W70°C. The amount of the additive is arbitrary, however, higher amount gives slower release of BAPC. The deliquescent property of BAPC can be suppressed by the addition of the above additives having higher affinity to BAPC.
COPYRIGHT: (C)1980,JPO&Japio
JP16183078A 1978-12-26 1978-12-26 Stabilization of bacanpicillin hydrochloride Granted JPS5587715A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16183078A JPS5587715A (en) 1978-12-26 1978-12-26 Stabilization of bacanpicillin hydrochloride

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16183078A JPS5587715A (en) 1978-12-26 1978-12-26 Stabilization of bacanpicillin hydrochloride

Publications (2)

Publication Number Publication Date
JPS5587715A true JPS5587715A (en) 1980-07-02
JPS5713529B2 JPS5713529B2 (en) 1982-03-17

Family

ID=15742719

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16183078A Granted JPS5587715A (en) 1978-12-26 1978-12-26 Stabilization of bacanpicillin hydrochloride

Country Status (1)

Country Link
JP (1) JPS5587715A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05194218A (en) * 1991-11-20 1993-08-03 Takeda Chem Ind Ltd Oral medicine composition and its production
WO2011052500A1 (en) * 2009-10-28 2011-05-05 第一三共株式会社 Wax stable formulation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4848616A (en) * 1971-10-05 1973-07-10
JPS4981526A (en) * 1972-12-14 1974-08-06
JPS49107855A (en) * 1973-02-03 1974-10-14

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4848616A (en) * 1971-10-05 1973-07-10
JPS4981526A (en) * 1972-12-14 1974-08-06
JPS49107855A (en) * 1973-02-03 1974-10-14

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05194218A (en) * 1991-11-20 1993-08-03 Takeda Chem Ind Ltd Oral medicine composition and its production
WO2011052500A1 (en) * 2009-10-28 2011-05-05 第一三共株式会社 Wax stable formulation

Also Published As

Publication number Publication date
JPS5713529B2 (en) 1982-03-17

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