JPS5587793A - Carcinostatic meso-tetra(p-carboxyphenyl)porphine derivative - Google Patents

Carcinostatic meso-tetra(p-carboxyphenyl)porphine derivative

Info

Publication number
JPS5587793A
JPS5587793A JP16256578A JP16256578A JPS5587793A JP S5587793 A JPS5587793 A JP S5587793A JP 16256578 A JP16256578 A JP 16256578A JP 16256578 A JP16256578 A JP 16256578A JP S5587793 A JPS5587793 A JP S5587793A
Authority
JP
Japan
Prior art keywords
anticarcinogenic
carboxyphenyl
meso
tetra
carcinostatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16256578A
Other languages
Japanese (ja)
Other versions
JPS6326087B2 (en
Inventor
Atsukore Takanabe
Yoshio Arakawa
Daisuke Sato
Ryozo Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
GC Biopharma Corp
Original Assignee
Green Cross Corp
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp, Green Cross Corp Korea filed Critical Green Cross Corp
Priority to JP16256578A priority Critical patent/JPS5587793A/en
Publication of JPS5587793A publication Critical patent/JPS5587793A/en
Publication of JPS6326087B2 publication Critical patent/JPS6326087B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Anticarcinogenic meso-tetra(p-carboxyphenyl)porphine derivatives of formula I (R1, R2, R3 and R4 are hydroxyl or residues of anticarcinogenic substances where at least one of the four groups is the residue of anticarcinogenic substance) and their alkali metal salts.
USE: Anticarcinogenic agent.
PREPARATION: The dehydrohalogenation between meso-tetra(p-carboxyphenyl) porphine derivative of formula II (R is halogen) and an anticarcisogenic agent bearing amino or imino group or hydroxyl group is effected to give title compound. The anticarcinogenic substance is, e.g., anthramycin, mitomycin C,8-azaguanine, etc.
COPYRIGHT: (C)1980,JPO&Japio
JP16256578A 1978-12-27 1978-12-27 Carcinostatic meso-tetra(p-carboxyphenyl)porphine derivative Granted JPS5587793A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16256578A JPS5587793A (en) 1978-12-27 1978-12-27 Carcinostatic meso-tetra(p-carboxyphenyl)porphine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16256578A JPS5587793A (en) 1978-12-27 1978-12-27 Carcinostatic meso-tetra(p-carboxyphenyl)porphine derivative

Publications (2)

Publication Number Publication Date
JPS5587793A true JPS5587793A (en) 1980-07-02
JPS6326087B2 JPS6326087B2 (en) 1988-05-27

Family

ID=15756998

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16256578A Granted JPS5587793A (en) 1978-12-27 1978-12-27 Carcinostatic meso-tetra(p-carboxyphenyl)porphine derivative

Country Status (1)

Country Link
JP (1) JPS5587793A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6113A (en) * 1982-09-27 1986-01-06 ヘルス・リサーチ・インコーポレーテツド Photosensitive drug for tumor, manufacture and apparatus
JPS61130220A (en) * 1984-11-26 1986-06-18 エフアモル・リミテツド Manufacture of antitumoral drug

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6113A (en) * 1982-09-27 1986-01-06 ヘルス・リサーチ・インコーポレーテツド Photosensitive drug for tumor, manufacture and apparatus
JPS61130220A (en) * 1984-11-26 1986-06-18 エフアモル・リミテツド Manufacture of antitumoral drug

Also Published As

Publication number Publication date
JPS6326087B2 (en) 1988-05-27

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