JPS5592689A - Antitumor substance, and drug containing the same - Google Patents

Antitumor substance, and drug containing the same

Info

Publication number
JPS5592689A
JPS5592689A JP16115978A JP16115978A JPS5592689A JP S5592689 A JPS5592689 A JP S5592689A JP 16115978 A JP16115978 A JP 16115978A JP 16115978 A JP16115978 A JP 16115978A JP S5592689 A JPS5592689 A JP S5592689A
Authority
JP
Japan
Prior art keywords
active substance
mycobacterium
coagulant
centrifuged
strain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP16115978A
Other languages
Japanese (ja)
Inventor
Shizuo Shimada
Tadashi Sudo
Hitoshi Inoue
Yoshio Furuya
Yoshikazu Fujisawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP16115978A priority Critical patent/JPS5592689A/en
Publication of JPS5592689A publication Critical patent/JPS5592689A/en
Pending legal-status Critical Current

Links

Landscapes

  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To obtain an active substance having antitumor activity or adjuvant activity, by extracting cells of bacteria belonging to Mycobacterium genus with an aqueous medium.
CONSTITUTION: Cells of bacteria belonging to Mycobacterium genus, e.g. Mycobacterium bovis BCG Nippon strain, Mycobacterium tuberculosis Aoyama B strain, etc. are disintegrated, and the dispersion is filtered or centrifuged to obtain a cell- free extract. The extract is precipitated with a coagulant such as aluminum sulfate, streptomycin, etc., suspended again in an aqueous medium of pH≥5 to elute the soluble components, and filtered or centrifuged after the removal of the coagulant to remove the insoluble components. The solution of the active substance thus prepared is, if necessary, freeze-dried to obtain the solid active substance.
COPYRIGHT: (C)1980,JPO&Japio
JP16115978A 1978-12-28 1978-12-28 Antitumor substance, and drug containing the same Pending JPS5592689A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16115978A JPS5592689A (en) 1978-12-28 1978-12-28 Antitumor substance, and drug containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16115978A JPS5592689A (en) 1978-12-28 1978-12-28 Antitumor substance, and drug containing the same

Publications (1)

Publication Number Publication Date
JPS5592689A true JPS5592689A (en) 1980-07-14

Family

ID=15729708

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16115978A Pending JPS5592689A (en) 1978-12-28 1978-12-28 Antitumor substance, and drug containing the same

Country Status (1)

Country Link
JP (1) JPS5592689A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100339398C (en) * 2005-12-22 2007-09-26 浙江万马药业有限公司 Bacterial-breaking process druing procedure of BCG acid powder polysaccharide and nucleic

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100339398C (en) * 2005-12-22 2007-09-26 浙江万马药业有限公司 Bacterial-breaking process druing procedure of BCG acid powder polysaccharide and nucleic

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