JPS56144094A - Preparation of mycophenolic acid by fungus - Google Patents
Preparation of mycophenolic acid by fungusInfo
- Publication number
- JPS56144094A JPS56144094A JP4592080A JP4592080A JPS56144094A JP S56144094 A JPS56144094 A JP S56144094A JP 4592080 A JP4592080 A JP 4592080A JP 4592080 A JP4592080 A JP 4592080A JP S56144094 A JPS56144094 A JP S56144094A
- Authority
- JP
- Japan
- Prior art keywords
- mycophenolic acid
- penicillium
- fungus
- preparation
- compactum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- HPNSFSBZBAHARI-UHFFFAOYSA-N micophenolic acid Natural products OC1=C(CC=C(C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-UHFFFAOYSA-N 0.000 title abstract 5
- HPNSFSBZBAHARI-RUDMXATFSA-N mycophenolic acid Chemical compound OC1=C(C\C=C(/C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-RUDMXATFSA-N 0.000 title abstract 5
- 229960000951 mycophenolic acid Drugs 0.000 title abstract 5
- 241000233866 Fungi Species 0.000 title abstract 3
- 241000228143 Penicillium Species 0.000 abstract 2
- 241000228145 Penicillium brevicompactum Species 0.000 abstract 2
- KNHUKKLJHYUCFP-UHFFFAOYSA-N clofibrate Chemical compound CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 KNHUKKLJHYUCFP-UHFFFAOYSA-N 0.000 abstract 2
- 229960001214 clofibrate Drugs 0.000 abstract 2
- 229940098377 penicillium brevicompactum Drugs 0.000 abstract 2
- 230000001939 inductive effect Effects 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To improve the productivity of mycophenolic acid, by cultivating a mycophenolic acid producing fungus having clofibrate resistance belonging to the genus Penicillium.
CONSTITUTION: A clofibrate resistant strain of mycophenolic acid producing fungus belonging to the genus Penicillium, e.g., Penicillium brevi-compactum AJ117090 FERM-P5474, etc., inducible strain from Penicillium brevi-compactum ATCC16024, is cultivated in a well-known nutrient medium. Mycophenolic acid accumulated in the medium is separated and collected by a well-known method.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4592080A JPS5853918B2 (en) | 1980-04-08 | 1980-04-08 | Production method of mycophenolic acid using microorganisms |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4592080A JPS5853918B2 (en) | 1980-04-08 | 1980-04-08 | Production method of mycophenolic acid using microorganisms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56144094A true JPS56144094A (en) | 1981-11-10 |
| JPS5853918B2 JPS5853918B2 (en) | 1983-12-01 |
Family
ID=12732678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4592080A Expired JPS5853918B2 (en) | 1980-04-08 | 1980-04-08 | Production method of mycophenolic acid using microorganisms |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5853918B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006038218A1 (en) * | 2004-10-05 | 2006-04-13 | Biocon Limited | Process for producing mycophenolic acid using penicillium arenicola bicc7673 |
-
1980
- 1980-04-08 JP JP4592080A patent/JPS5853918B2/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006038218A1 (en) * | 2004-10-05 | 2006-04-13 | Biocon Limited | Process for producing mycophenolic acid using penicillium arenicola bicc7673 |
| JP2008515422A (en) * | 2004-10-05 | 2008-05-15 | バイオコン・リミテッド | A method for producing mycophenolic acid using Penicillium arenicola BICC7673. |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5853918B2 (en) | 1983-12-01 |
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