JPS56145292A - Cephalosporin derivative - Google Patents

Cephalosporin derivative

Info

Publication number
JPS56145292A
JPS56145292A JP4767480A JP4767480A JPS56145292A JP S56145292 A JPS56145292 A JP S56145292A JP 4767480 A JP4767480 A JP 4767480A JP 4767480 A JP4767480 A JP 4767480A JP S56145292 A JPS56145292 A JP S56145292A
Authority
JP
Japan
Prior art keywords
formula
pyrazino
quinoline
hydroxy
positive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4767480A
Other languages
Japanese (ja)
Inventor
Yoshiaki Watanabe
Chihiro Yokoo
Toshibumi Asaga
Akira Onodera
Kaoru Soda
Jiro Sawada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Priority to JP4767480A priority Critical patent/JPS56145292A/en
Publication of JPS56145292A publication Critical patent/JPS56145292A/en
Pending legal-status Critical Current

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  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Cephalosporin derivatives of formula I (X is H, hydroxyl) and their salts.
EXAMPLE: 7-[ D-α-(4-Hydroxy-pyrazino[ 2,3-f ]quinoline-3-carboxamide-α-pheuylacetamide ]cephalosporinic sodium salt.
USE: Antibiotic and its synthetic intermediate: they are effective on gram-positive and -negative bacteria, especially show remarkable effect on Pseudomonas areuginosa, indole-positive myxomeycetes, pneumobacillus or the like.
PREPARATION: For example, a compound of formula II is acylated with 4-hydroxy- pyrazino [2,3-f]quinoline-3-carboxylic acid or its reactive derivative to give the compound of formula I. The reaction is conducted in a solvent such as water or chloroform, when necessary, under heating.
COPYRIGHT: (C)1981,JPO&Japio
JP4767480A 1980-04-11 1980-04-11 Cephalosporin derivative Pending JPS56145292A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4767480A JPS56145292A (en) 1980-04-11 1980-04-11 Cephalosporin derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4767480A JPS56145292A (en) 1980-04-11 1980-04-11 Cephalosporin derivative

Publications (1)

Publication Number Publication Date
JPS56145292A true JPS56145292A (en) 1981-11-11

Family

ID=12781811

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4767480A Pending JPS56145292A (en) 1980-04-11 1980-04-11 Cephalosporin derivative

Country Status (1)

Country Link
JP (1) JPS56145292A (en)

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