JPS5630980A - Codeinone 7,8-oxide - Google Patents

Codeinone 7,8-oxide

Info

Publication number
JPS5630980A
JPS5630980A JP10781579A JP10781579A JPS5630980A JP S5630980 A JPS5630980 A JP S5630980A JP 10781579 A JP10781579 A JP 10781579A JP 10781579 A JP10781579 A JP 10781579A JP S5630980 A JPS5630980 A JP S5630980A
Authority
JP
Japan
Prior art keywords
codeinone
formula
oxide
action
butylhydroperoxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10781579A
Other languages
Japanese (ja)
Other versions
JPS6145991B2 (en
Inventor
Kiyoko Uba
Naoki Miyata
Keizo Watanabe
Masaaki Hirobe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Priority to JP10781579A priority Critical patent/JPS5630980A/en
Publication of JPS5630980A publication Critical patent/JPS5630980A/en
Publication of JPS6145991B2 publication Critical patent/JPS6145991B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A codeinone 7,8-oxide shown by the formula I.
USE: A drug having action, e.g., pain-killing, antitussive and sedative action, etc.
PROCESS: For example, codeinone shown by the formula II is reacted with an oxidizing agent, e.g., hydroperoxide, t-butylhydroperoxide, etc. in a solvent, e.g., water, methanol, methylene chloride, etc. in the presence of a base, preferably an alkali carbonate, etc. to give a compound shown by the formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP10781579A 1979-08-24 1979-08-24 Codeinone 7,8-oxide Granted JPS5630980A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10781579A JPS5630980A (en) 1979-08-24 1979-08-24 Codeinone 7,8-oxide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10781579A JPS5630980A (en) 1979-08-24 1979-08-24 Codeinone 7,8-oxide

Publications (2)

Publication Number Publication Date
JPS5630980A true JPS5630980A (en) 1981-03-28
JPS6145991B2 JPS6145991B2 (en) 1986-10-11

Family

ID=14468728

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10781579A Granted JPS5630980A (en) 1979-08-24 1979-08-24 Codeinone 7,8-oxide

Country Status (1)

Country Link
JP (1) JPS5630980A (en)

Also Published As

Publication number Publication date
JPS6145991B2 (en) 1986-10-11

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