JPS5634699A - (2'-5')polyadenylic acid compound and its preparation - Google Patents
(2'-5')polyadenylic acid compound and its preparationInfo
- Publication number
- JPS5634699A JPS5634699A JP11152379A JP11152379A JPS5634699A JP S5634699 A JPS5634699 A JP S5634699A JP 11152379 A JP11152379 A JP 11152379A JP 11152379 A JP11152379 A JP 11152379A JP S5634699 A JPS5634699 A JP S5634699A
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- substituted
- acid compound
- polyadenylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Saccharide Compounds (AREA)
Abstract
NEW MATERIAL:A (2'-5')polyadenylic acid compound of formula I [the group of formula II is a residue of the group of formula III; NB is o-nitro-4- and/or 5-substituted or unsubstituted benzyl; n is 0W2], or its salt.
USE: An intermediate for the synthesis of 5'-triphosphoryladenylyl-(2'-5')-adenylyl- (2'-5')adenosine which is a protein-synthesis inhibiting material.
PROCESS: The objective compound of formula I is prepared by (1) condensing N6- acyl or substituted or unsubstituted trityl-3'-O[o-nitro-4- and/or 5-substituted or unsubstituted benzyl]adenosine-monophosphate by reacting with a condensing agent (2) hydrolyzing the condensation product to eliminate the N6-acyl group or the N6- trityl group, and if nexessary, (3) converting the free acid thus obtained to a salt.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11152379A JPS5634699A (en) | 1979-08-31 | 1979-08-31 | (2'-5')polyadenylic acid compound and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11152379A JPS5634699A (en) | 1979-08-31 | 1979-08-31 | (2'-5')polyadenylic acid compound and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5634699A true JPS5634699A (en) | 1981-04-06 |
| JPS6126915B2 JPS6126915B2 (en) | 1986-06-23 |
Family
ID=14563481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11152379A Granted JPS5634699A (en) | 1979-08-31 | 1979-08-31 | (2'-5')polyadenylic acid compound and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5634699A (en) |
-
1979
- 1979-08-31 JP JP11152379A patent/JPS5634699A/en active Granted
Non-Patent Citations (1)
| Title |
|---|
| CHEM. PHARM. BULL.=1977 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6126915B2 (en) | 1986-06-23 |
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