JPS5653101A - Polysaccharide ks-2-d and its preparation - Google Patents
Polysaccharide ks-2-d and its preparationInfo
- Publication number
- JPS5653101A JPS5653101A JP12073679A JP12073679A JPS5653101A JP S5653101 A JPS5653101 A JP S5653101A JP 12073679 A JP12073679 A JP 12073679A JP 12073679 A JP12073679 A JP 12073679A JP S5653101 A JPS5653101 A JP S5653101A
- Authority
- JP
- Japan
- Prior art keywords
- average
- molecular weight
- water
- polysaccharide
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000004676 glycans Chemical class 0.000 title abstract 2
- 229920001282 polysaccharide Polymers 0.000 title abstract 2
- 239000005017 polysaccharide Substances 0.000 title abstract 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000001720 carbohydrates Chemical class 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- FIHZWZBEAXASKA-UHFFFAOYSA-N Anthron Natural products COc1cc2Cc3cc(C)cc(O)c3C(=O)c2c(O)c1C=CC(C)C FIHZWZBEAXASKA-UHFFFAOYSA-N 0.000 abstract 1
- 241000222120 Candida <Saccharomycetales> Species 0.000 abstract 1
- 235000001715 Lentinula edodes Nutrition 0.000 abstract 1
- 240000000599 Lentinula edodes Species 0.000 abstract 1
- 241000186781 Listeria Species 0.000 abstract 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 abstract 1
- 230000003327 cancerostatic effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000921 elemental analysis Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- OQUKIQWCVTZJAF-UHFFFAOYSA-N phenol;sulfuric acid Chemical compound OS(O)(=O)=O.OC1=CC=CC=C1 OQUKIQWCVTZJAF-UHFFFAOYSA-N 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000010186 staining Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- HNONEKILPDHFOL-UHFFFAOYSA-M tolonium chloride Chemical compound [Cl-].C1=C(C)C(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 HNONEKILPDHFOL-UHFFFAOYSA-M 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
NEW MATERIAL:A polysaccharide, KS-2-D, having the following physical and chemical properties. Elemental analysis, C 42.3±1.5%, H 6.2±0.3%, N 0.6± 0.2%, ash 6.7± 2.5%; molecular weight, 30,000W70,000, average molecular weight, 70,000; white amorphous powder; decomposition point, 185°C (Capillary method); pH=7W8, nearly neutral; soluble in water, insoluble in ethanol, acetone, n-hexane, etc.; specific rotation, [α]D21=+66.1W+97.5° (average 82.9°) (water, c=0.5%); positive to phenol-sulfuric acid reaction, anthron reaction, etc., negative to toluidine blue O staining; saccharide content, 65W80% (average 71%), protein content, 3.5W6% (average 4.8%), protein/saccharide ratio, 0.05W0.08 (average 0.07), etc.
USE: Carcinostatic agent. Preventive and remedy for diseases caused by candida, Pseudomonas aeruginosa, Listeria, influenza virus, etc.
PROCESS: The compound can be prepared by culturing strain of Lentinus edodes KSLE 28 (FERM-P No.4196), etc.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12073679A JPS5653101A (en) | 1979-09-21 | 1979-09-21 | Polysaccharide ks-2-d and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12073679A JPS5653101A (en) | 1979-09-21 | 1979-09-21 | Polysaccharide ks-2-d and its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5653101A true JPS5653101A (en) | 1981-05-12 |
Family
ID=14793706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12073679A Pending JPS5653101A (en) | 1979-09-21 | 1979-09-21 | Polysaccharide ks-2-d and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5653101A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1774012A2 (en) * | 2004-07-16 | 2007-04-18 | Medimush A/S | Immune modulating compounds from fungi |
| US7514085B2 (en) | 2004-07-16 | 2009-04-07 | Medimush A/S | Immune modulating compounds from fungi |
| US10471135B2 (en) | 2001-09-03 | 2019-11-12 | Glycanova As | Production of fungal extracellular immune stimulating compounds |
-
1979
- 1979-09-21 JP JP12073679A patent/JPS5653101A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10471135B2 (en) | 2001-09-03 | 2019-11-12 | Glycanova As | Production of fungal extracellular immune stimulating compounds |
| EP1774012A2 (en) * | 2004-07-16 | 2007-04-18 | Medimush A/S | Immune modulating compounds from fungi |
| US7514085B2 (en) | 2004-07-16 | 2009-04-07 | Medimush A/S | Immune modulating compounds from fungi |
| US7682615B2 (en) | 2004-07-16 | 2010-03-23 | Beka Holding As | Immune modulating compounds from fungi |
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