JPS567721A - Preparation of immunoglobulin for intravenous injection - Google Patents

Preparation of immunoglobulin for intravenous injection

Info

Publication number
JPS567721A
JPS567721A JP8380079A JP8380079A JPS567721A JP S567721 A JPS567721 A JP S567721A JP 8380079 A JP8380079 A JP 8380079A JP 8380079 A JP8380079 A JP 8380079A JP S567721 A JPS567721 A JP S567721A
Authority
JP
Japan
Prior art keywords
intravenous injection
immunoglobulin
plasmin
preparation
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8380079A
Other languages
Japanese (ja)
Inventor
Haruo Onishi
Masahiro Nobuhara
Yasuo Suzuki
Suguru Mochida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mochida Pharmaceutical Co Ltd
Original Assignee
Mochida Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharmaceutical Co Ltd filed Critical Mochida Pharmaceutical Co Ltd
Priority to JP8380079A priority Critical patent/JPS567721A/en
Publication of JPS567721A publication Critical patent/JPS567721A/en
Pending legal-status Critical Current

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PURPOSE: To prepare immunoglobulin for intravenous injection, without plasmin-removing process, by treating human immunoglobulin with immobilized plasmin.
CONSTITUTION: Immunoglobulin for intravenous injection is prepared by treating human immunoglobulin, esp. gamma globulin with plasmin or plasminogen fixed to an insoluble carrier (e.g. Sephalose 4B). Since the plasmin is fixed to the carrier, there is no troubles of contaminating the product with the enzyme, and therefore, the enzyme-removal process is not necessary. The anticomplementary activity of the globulin thus prepared is sufficiently low for the intravenous injection.
COPYRIGHT: (C)1981,JPO&Japio
JP8380079A 1979-07-02 1979-07-02 Preparation of immunoglobulin for intravenous injection Pending JPS567721A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8380079A JPS567721A (en) 1979-07-02 1979-07-02 Preparation of immunoglobulin for intravenous injection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8380079A JPS567721A (en) 1979-07-02 1979-07-02 Preparation of immunoglobulin for intravenous injection

Publications (1)

Publication Number Publication Date
JPS567721A true JPS567721A (en) 1981-01-27

Family

ID=13812724

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8380079A Pending JPS567721A (en) 1979-07-02 1979-07-02 Preparation of immunoglobulin for intravenous injection

Country Status (1)

Country Link
JP (1) JPS567721A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT383739B (en) * 1983-03-16 1987-08-10 Immuno Ag METHOD FOR INACTIVATING SUBSTANCES CAUSING INCOMPATIBILITY REACTIONS IN IMMUNALLOBULIN BLOOD FRACTIONS
AT383738B (en) * 1983-03-16 1987-08-10 Immuno Ag METHOD FOR USING A FRACTION CONTAINING IMMUNGLOBULIN-G
AT383737B (en) * 1983-03-16 1987-08-10 Immuno Ag METHOD FOR USING AN IMMUNOGLOBULIN-G FRACTION
JPS62503036A (en) * 1985-05-30 1987-12-03 アンスチチユ　メリユ Method for preparing gamma globulin administered intravenously and gamma globulin obtained by the method
JPS62286932A (en) * 1986-05-30 1987-12-12 イムノ・アクチエンゲゼルシャフト Inactivation of proliferative filterable pathogen

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT383739B (en) * 1983-03-16 1987-08-10 Immuno Ag METHOD FOR INACTIVATING SUBSTANCES CAUSING INCOMPATIBILITY REACTIONS IN IMMUNALLOBULIN BLOOD FRACTIONS
AT383738B (en) * 1983-03-16 1987-08-10 Immuno Ag METHOD FOR USING A FRACTION CONTAINING IMMUNGLOBULIN-G
AT383737B (en) * 1983-03-16 1987-08-10 Immuno Ag METHOD FOR USING AN IMMUNOGLOBULIN-G FRACTION
US4886758A (en) * 1983-03-16 1989-12-12 Immuno Aktiengesellschaft Fur Chemisch-Medizinische Produkte Method of determining incompatibility-reaction-causing substances in blood products as well as a method of inactivating said incompatibility-reaction-causing substances
JPS62503036A (en) * 1985-05-30 1987-12-03 アンスチチユ　メリユ Method for preparing gamma globulin administered intravenously and gamma globulin obtained by the method
JPS62286932A (en) * 1986-05-30 1987-12-12 イムノ・アクチエンゲゼルシャフト Inactivation of proliferative filterable pathogen

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