JPS5677272A - Monoester compound of kojic acid - Google Patents
Monoester compound of kojic acidInfo
- Publication number
- JPS5677272A JPS5677272A JP15382179A JP15382179A JPS5677272A JP S5677272 A JPS5677272 A JP S5677272A JP 15382179 A JP15382179 A JP 15382179A JP 15382179 A JP15382179 A JP 15382179A JP S5677272 A JPS5677272 A JP S5677272A
- Authority
- JP
- Japan
- Prior art keywords
- kojic acid
- monoester compound
- kojic
- chromatodermatosis
- melain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BEJNERDRQOWKJM-UHFFFAOYSA-N kojic acid Chemical compound OCC1=CC(=O)C(O)=CO1 BEJNERDRQOWKJM-UHFFFAOYSA-N 0.000 title abstract 5
- 229960004705 kojic acid Drugs 0.000 title abstract 5
- WZNJWVWKTVETCG-UHFFFAOYSA-N kojic acid Natural products OC(=O)C(N)CN1C=CC(=O)C(O)=C1 WZNJWVWKTVETCG-UHFFFAOYSA-N 0.000 title abstract 5
- 150000001875 compounds Chemical class 0.000 title abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 206010042496 Sunburn Diseases 0.000 abstract 1
- 102000003425 Tyrosinase Human genes 0.000 abstract 1
- 108060008724 Tyrosinase Proteins 0.000 abstract 1
- 150000007933 aliphatic carboxylic acids Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 108010038270 melain Proteins 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000003405 preventing effect Effects 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 230000002087 whitening effect Effects 0.000 abstract 1
Landscapes
- Pyrane Compounds (AREA)
- Cosmetics (AREA)
Abstract
NEW MATERIAL:A monoester compound of kojic acid shown by the formula (R is 3W20C aliphatic acyl).
EXAMPLE: Monopalmitate of kojic acid.
USE: A whitening cosmetic. Inhibiting the activity of tyrosinase occurring in the human skin, exhibiting an extremely suppressing action of melain formation, showing improved beautifying effect and preventing effect of sunburn, and effective against chromatodermatosis, etc. Having high stability to pH, light, heat, etc., improved shelf stability, solubility in oil, and nontoxic to the human body.
PROCESS: For example, an aliphatic carboxylic acid chloride is added to a solution of kojic acid in pyridine and kojic acid is esterified.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15382179A JPS5822152B2 (en) | 1979-11-27 | 1979-11-27 | Kojic acid monoester |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15382179A JPS5822152B2 (en) | 1979-11-27 | 1979-11-27 | Kojic acid monoester |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5677272A true JPS5677272A (en) | 1981-06-25 |
| JPS5822152B2 JPS5822152B2 (en) | 1983-05-06 |
Family
ID=15570820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15382179A Expired JPS5822152B2 (en) | 1979-11-27 | 1979-11-27 | Kojic acid monoester |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5822152B2 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5486624A (en) * | 1994-02-01 | 1996-01-23 | Pacific Corporation | Kojic acid derivative |
| US5523421A (en) * | 1993-11-16 | 1996-06-04 | Pacific Corporation | Kojic acid derivatives |
| US5599528A (en) * | 1993-09-30 | 1997-02-04 | Sansho Seiyaku Co., Ltd. | Preparation for epidermis |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002293728A (en) * | 2001-03-30 | 2002-10-09 | Sansho Seiyaku Co Ltd | Astringent cosmetic |
| JP2002293729A (en) * | 2001-03-30 | 2002-10-09 | Sansho Seiyaku Co Ltd | Tissue-repairing agent |
-
1979
- 1979-11-27 JP JP15382179A patent/JPS5822152B2/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5599528A (en) * | 1993-09-30 | 1997-02-04 | Sansho Seiyaku Co., Ltd. | Preparation for epidermis |
| US5523421A (en) * | 1993-11-16 | 1996-06-04 | Pacific Corporation | Kojic acid derivatives |
| US5486624A (en) * | 1994-02-01 | 1996-01-23 | Pacific Corporation | Kojic acid derivative |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5822152B2 (en) | 1983-05-06 |
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