JPS5677281A - Antibiotic heptelidic acid and its preparation - Google Patents

Antibiotic heptelidic acid and its preparation

Info

Publication number
JPS5677281A
JPS5677281A JP15467979A JP15467979A JPS5677281A JP S5677281 A JPS5677281 A JP S5677281A JP 15467979 A JP15467979 A JP 15467979A JP 15467979 A JP15467979 A JP 15467979A JP S5677281 A JPS5677281 A JP S5677281A
Authority
JP
Japan
Prior art keywords
antibiotic
strain
ferm
filtrate
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15467979A
Other languages
Japanese (ja)
Inventor
Mamoru Arai
Tatsuo Haishi
Yasuhiro Ito
Hideji Takahashi
Kohei Furuya
Kentaro Kodama
Hiroshi Takiguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP15467979A priority Critical patent/JPS5677281A/en
Publication of JPS5677281A publication Critical patent/JPS5677281A/en
Pending legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Heptelicid acid shown by the formula and its salt.
USE: An antibiotic. Effective against an obligate Gram-negative bacterium, especially against Bacteroides fragilis, having a strong antibacterial activity against a cliincally separated strain as well as a sensitive bacterium.
PROCESS: A strain SANK 12679(FERM-P 5284) of Gliocladium Virens, strain SANK 13379 (FERM-P 5284) of Cheatomim globosum, or strain SANK 13479 (FREM-P 5282) of Trichlderma viride is cultivated in a liquid medium at 20W 30°C to give a culture solution, which is filterted or centrifuged. Heptelidic acid shown by the formula is extracted or purified from the filtrate or the supernatant liquid. The extraction, example, is carried out by passing for the filtrate through a layer of active carbon, etc. so that impurities are adsorbed and removed.
COPYRIGHT: (C)1981,JPO&Japio
JP15467979A 1979-11-29 1979-11-29 Antibiotic heptelidic acid and its preparation Pending JPS5677281A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15467979A JPS5677281A (en) 1979-11-29 1979-11-29 Antibiotic heptelidic acid and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15467979A JPS5677281A (en) 1979-11-29 1979-11-29 Antibiotic heptelidic acid and its preparation

Publications (1)

Publication Number Publication Date
JPS5677281A true JPS5677281A (en) 1981-06-25

Family

ID=15589536

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15467979A Pending JPS5677281A (en) 1979-11-29 1979-11-29 Antibiotic heptelidic acid and its preparation

Country Status (1)

Country Link
JP (1) JPS5677281A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011016351A1 (en) * 2009-08-07 2011-02-10 学校法人神戸学院 Dna synthase inhibitors
JP2016140291A (en) * 2015-01-30 2016-08-08 公益財団法人野田産業科学研究所 Antibacterial substance

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011016351A1 (en) * 2009-08-07 2011-02-10 学校法人神戸学院 Dna synthase inhibitors
JP2011037730A (en) * 2009-08-07 2011-02-24 Kobe Gakuin Dna synthase inhibitor
JP2016140291A (en) * 2015-01-30 2016-08-08 公益財団法人野田産業科学研究所 Antibacterial substance

Similar Documents

Publication Publication Date Title
LU79216A1 (en) PROCESS FOR THE PREPARATION OF NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
PT66353A (en) PROCESS FOR THE PREPARATION OF NOVEL ALCOHOLSHIPS DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
LU81104A1 (en) NEW O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICINAL PRODUCTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
PT66099B (en) PROCESS FOR THE PREPARATION OF NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
IE820137L (en) Phosphoryl compounds
JPS5592387A (en) Antibiotic substance tm-531
JPS5543011A (en) 7-halothiazolylalkoxyiminoacetamido-3-cephem compound
LU79313A1 (en) PROCESS FOR THE PREPARATION OF NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
JPS5739798A (en) Prepartion of deacetylcephalosporin c or its salt and acetyl esterase used for it
BE872497A (en) NEW OXIMES DERIVED FROM 3-SUBSTITUTE 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIQUE, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
JPS5677281A (en) Antibiotic heptelidic acid and its preparation
JPS57131758A (en) 1-sulfo-2-oxoazetidine derivative, its preparation and use
PT66944B (en) PROCESS FOR THE PREPARATION OF NOVEL OXIMES DERIVED FROM 3-CARBAMOYLOXYMETHYL 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
PT69490A (en) PROCESS FOR THE PREPARATION OF NOVEL OXIMES DERIVED FROM 3-AZIDOMETHYL 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
EP0076452A3 (en) Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
JPS532404A (en) Elimination of thiol protectors
LU79998A1 (en) PROCESS FOR THE PREPARATION OF NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDE CEPHALOSPORANIC
JPS54106491A (en) Cephalosporin analog or its salt, their preparation, and prophylactics and remedies for microbisms consisting mainly of them
JPS5555198A (en) Novel antibiotic substance
JPS56140957A (en) Antibiotic mycoplanecin b, its derivative and preparation thereof
JPS5711977A (en) Purifying method of 5-acetamido-1,2,3-thiadiazole
JPS5785394A (en) Novel cephem compound, its preparation, preventive and remedy for bacterium infectious disease comprising it
JPS55151597A (en) New material 2-hydroxysagamicin and its preparation
JPS52108572A (en) Magnetic separator
JPS5239852A (en) Heat exchange plant