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Mitsubishi Chemical Corp
Original Assignee
Mitsubishi Chemical Industries Ltd
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Filing date
Publication date
Application filed by Mitsubishi Chemical Industries LtdfiledCriticalMitsubishi Chemical Industries Ltd
Priority to JP8362679ApriorityCriticalpatent/JPS567767A/en
Publication of JPS567767ApublicationCriticalpatent/JPS567767A/en
Publication of JPS6157829B2publicationCriticalpatent/JPS6157829B2/ja
USE: Carcinostatic agent. The hexamethylene derivative has superior offect. The conversion of an alkylene dipyridinesulfonate to an N-oxide derivative remarkably improves the activity.
PROCESS: The compound of formula is prepared by oxidizing an alkylene dipyridinesulfonate in a solvent such as chloroform, dichloromethane, etc. with an oxidizing agent such as hydrogen peroxide, pref. m-chloroperbenzoic acid.