JPS57114554A - N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agent - Google Patents

N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agent

Info

Publication number: JPS57114554A
Authority: JP; Japan
Prior art keywords: validamine; glucosidase inhibiting; inhibiting agent; derivative; alpha
Prior art date: 1981-01-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP56181A

Other languages

English (en)

Japanese (ja)

Other versions

JPH0161100B2 (mo

Inventor

Satoshi Horii

Yukihiko Kameda

Ou Fukase

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Takeda Pharmaceutical Co Ltd

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-01-05

Filing date

1981-01-05

Publication date

1982-07-16

1981-01-05 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1981-01-05 Priority to JP56181A priority Critical patent/JPS57114554A/ja

1981-12-24 Priority to EP81306141A priority patent/EP0056194B1/en

1981-12-24 Priority to DE8181306141T priority patent/DE3166093D1/de

1981-12-28 Priority to US06/334,986 priority patent/US4701559A/en

1982-01-04 Priority to CA000393545A priority patent/CA1184181A/en

1982-07-16 Publication of JPS57114554A publication Critical patent/JPS57114554A/ja

1987-04-17 Priority to US07/039,278 priority patent/US4777294A/en

1987-04-17 Priority to US07/039,277 priority patent/US4803303A/en

1989-12-27 Publication of JPH0161100B2 publication Critical patent/JPH0161100B2/ja

1992-06-17 Priority to MX9202937A priority patent/MX9202937A/es

Status Granted legal-status Critical Current

Links

GSQYAWMREAXBHF-UOYQFSTFSA-N validamine Chemical class N[C@H]1C[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GSQYAWMREAXBHF-UOYQFSTFSA-N 0.000 title abstract 5
102100024295 Maltase-glucoamylase Human genes 0.000 title abstract 3
108010028144 alpha-Glucosidases Proteins 0.000 title abstract 3
230000002401 inhibitory effect Effects 0.000 title abstract 3
GSQYAWMREAXBHF-UHFFFAOYSA-N Validamine Natural products NC1CC(CO)C(O)C(O)C1O GSQYAWMREAXBHF-UHFFFAOYSA-N 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
-1 phenoxy, thienyl Chemical group 0.000 abstract 2
125000004076 pyridyl group Chemical group 0.000 abstract 2
241001465754 Metazoa Species 0.000 abstract 1
239000002262 Schiff base Substances 0.000 abstract 1
150000004753 Schiff bases Chemical class 0.000 abstract 1
150000001299 aldehydes Chemical class 0.000 abstract 1
239000003674 animal food additive Substances 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
235000014633 carbohydrates Nutrition 0.000 abstract 1
150000001720 carbohydrates Chemical class 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
208000002925 dental caries Diseases 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
235000013373 food additive Nutrition 0.000 abstract 1
239000002778 food additive Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
201000001421 hyperglycemia Diseases 0.000 abstract 1
150000002576 ketones Chemical class 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
230000004060 metabolic process Effects 0.000 abstract 1
230000003449 preventive effect Effects 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Furan Compounds (AREA)
Pyridine Compounds (AREA)

JP56181A 1981-01-05 1981-01-05 N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agent Granted JPS57114554A (en)

Priority Applications (8)

Application Number	Priority Date	Filing Date	Title
JP56181A JPS57114554A (en)	1981-01-05	1981-01-05	N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agent
EP81306141A EP0056194B1 (en)	1981-01-05	1981-12-24	N-substituted pseudo-aminosugars, their production and use
DE8181306141T DE3166093D1 (en)	1981-01-05	1981-12-24	N-substituted pseudo-aminosugars, their production and use
US06/334,986 US4701559A (en)	1981-01-05	1981-12-28	N-substituted pseudo-aminosugars, their production and use
CA000393545A CA1184181A (en)	1981-01-05	1982-01-04	N-substituted pseudo-aminosugars, their production and use
US07/039,278 US4777294A (en)	1981-01-05	1987-04-17	N-substituted pseudo-aminosugars, their production and use
US07/039,277 US4803303A (en)	1981-01-05	1987-04-17	N-substituted pseudo-aminosugars, their production and use
MX9202937A MX9202937A (es)	1981-01-05	1992-06-17	Pseudo-aminoazucares n-substituidos.

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP56181A JPS57114554A (en)	1981-01-05	1981-01-05	N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agent

Publications (2)

Publication Number	Publication Date
JPS57114554A true JPS57114554A (en)	1982-07-16
JPH0161100B2 JPH0161100B2 (mo)	1989-12-27

Family

ID=11477129

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP56181A Granted JPS57114554A (en)	1981-01-05	1981-01-05	N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agent

Country Status (1)

Country	Link
JP (1)	JPS57114554A (mo)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2012011174A1 (ja) *	2010-07-22	2012-01-26	ビオフェルミン製薬株式会社	脂質代謝改善剤、脂質代謝改善作用増強剤、抗肥満剤及び抗肥満作用増強剤

1981
- 1981-01-05 JP JP56181A patent/JPS57114554A/ja active Granted

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2012011174A1 (ja) *	2010-07-22	2012-01-26	ビオフェルミン製薬株式会社	脂質代謝改善剤、脂質代謝改善作用増強剤、抗肥満剤及び抗肥満作用増強剤

Also Published As

Publication number	Publication date
JPH0161100B2 (mo)	1989-12-27

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