JPS57123145A - Production of p-hydroxyphenylacetic ester - Google Patents
Production of p-hydroxyphenylacetic esterInfo
- Publication number
- JPS57123145A JPS57123145A JP56008867A JP886781A JPS57123145A JP S57123145 A JPS57123145 A JP S57123145A JP 56008867 A JP56008867 A JP 56008867A JP 886781 A JP886781 A JP 886781A JP S57123145 A JPS57123145 A JP S57123145A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- phm
- hydroxyphenylacetic
- strong
- ion exchange
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PURPOSE: p-Hydroxymandelic acid is reduced in a solvent of lower alcohol in the presence of a strong-acid type ion exchange resin to produce the titled compound used as a synthetic intermediate of medicines and agricultural chemicals directly, not through its free acid, in high yield.
CONSTITUTION: p-Hydroxymandelic acid (PHM) of formulaIis reduced in an alcohol of 1W4C carbon atoms in the presence of a strong-acid type ion exchange resin to give a p-hydroxyphenylacetic ester of formula II (R is alkyl of 1W4C carbon atoms). The amount of alcohol is 5W15mol per 1mol of PHM and the strong-acid type ion exchange resin is 7W13W/V% based on PHM. The reduction reaction is catalytically effected in the presence of a Pd or Pt catalyst and three series of reactions proceed simultaneously. Since free p-hydroxyphenylacetic acid is not formed, the working environment is markedly improved as well as its purification and esterification processes are eliminated.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56008867A JPS57123145A (en) | 1981-01-23 | 1981-01-23 | Production of p-hydroxyphenylacetic ester |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56008867A JPS57123145A (en) | 1981-01-23 | 1981-01-23 | Production of p-hydroxyphenylacetic ester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS57123145A true JPS57123145A (en) | 1982-07-31 |
Family
ID=11704636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56008867A Pending JPS57123145A (en) | 1981-01-23 | 1981-01-23 | Production of p-hydroxyphenylacetic ester |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57123145A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007009590A1 (en) * | 2005-07-18 | 2007-01-25 | Dsm Ip Assets B.V. | Process for the preparation of phenolic compounds |
-
1981
- 1981-01-23 JP JP56008867A patent/JPS57123145A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007009590A1 (en) * | 2005-07-18 | 2007-01-25 | Dsm Ip Assets B.V. | Process for the preparation of phenolic compounds |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS57123145A (en) | Production of p-hydroxyphenylacetic ester | |
| MY132161A (en) | Process for the preparation of ammoxidation catalysts | |
| JPS53141216A (en) | Preparation of methacrylic acid ester | |
| JPS5424818A (en) | Preparation of high purity maleic acid monoalcohol ester | |
| GB1497992A (en) | Production of carboxy-alkane-phosphonic acids and carboxy-alkyl-phosphinic acids | |
| JPS57183749A (en) | Preparation of gamma-amino-beta-hydroxybutyric acid | |
| JPS5770845A (en) | Preparation of methacrylic acid dimenthylaminomethyl ester | |
| JPS51125252A (en) | Process for preparing substituted cyclopropanecarboxylic acid esters | |
| JPS5427507A (en) | Preparation of tertiary butyl alcohol | |
| JPS5219625A (en) | Process for preparation of organophosphorus compounds | |
| JPS5430104A (en) | Continuous production of tertiary butyl alcohol | |
| JPS5377010A (en) | Preparation of hydroxypivalic acid | |
| IE792291L (en) | Process for the manufacture of 5-mercapto-1,2,3-triazoles. | |
| JPS53124221A (en) | Preparation of phosphoroamidate having hydroxyalkyl group | |
| JPS5731629A (en) | Preparation of bisphenolethane | |
| JPS52139003A (en) | Synthesis of carboxylic acid esters | |
| JPS5714557A (en) | Production of malonic diester | |
| JPS57102850A (en) | Preparation of butyric acid derivative | |
| JPS5773000A (en) | Production of olean-1-2ene-3beta,30-diol | |
| JPS56158754A (en) | Preparation of p-ethoxycarbonylphenyl epsilon-guanidinocaproate | |
| JPS5430129A (en) | Preparation of toluic acid amide | |
| JPS5620544A (en) | Preparation of ethylene glycol monoethyl ether acetate | |
| JPS51138650A (en) | Process for preparing optically active trans-cyclopentene-3,5,-diolmon oester | |
| JPS6445A (en) | Production of 2-chloropropionaldehyde | |
| JPS5527015A (en) | Preparation of catalyst solution |