JPS57188554A - Elongated n-terminal somatostatin homologue - Google Patents

Elongated n-terminal somatostatin homologue

Info

Publication number
JPS57188554A
JPS57188554A JP57072520A JP7252082A JPS57188554A JP S57188554 A JPS57188554 A JP S57188554A JP 57072520 A JP57072520 A JP 57072520A JP 7252082 A JP7252082 A JP 7252082A JP S57188554 A JPS57188554 A JP S57188554A
Authority
JP
Japan
Prior art keywords
elongated
terminal
homologue
somatostatin homologue
terminal somatostatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57072520A
Other languages
English (en)
Japanese (ja)
Inventor
Uookaa Beeru Jiyuniaa Wairii
Edowaado Furederitsuku Ri Jiin
Rosu Buraun Maabin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Salk Institute for Biological Studies
Original Assignee
Salk Institute for Biological Studies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Institute for Biological Studies filed Critical Salk Institute for Biological Studies
Publication of JPS57188554A publication Critical patent/JPS57188554A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP57072520A 1981-04-29 1982-04-28 Elongated n-terminal somatostatin homologue Pending JPS57188554A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/258,878 US4393050A (en) 1981-04-29 1981-04-29 Analogs of extended N-terminal somatostatin

Publications (1)

Publication Number Publication Date
JPS57188554A true JPS57188554A (en) 1982-11-19

Family

ID=22982518

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57072520A Pending JPS57188554A (en) 1981-04-29 1982-04-28 Elongated n-terminal somatostatin homologue

Country Status (8)

Country Link
US (1) US4393050A (de)
EP (1) EP0063885B1 (de)
JP (1) JPS57188554A (de)
AU (1) AU547379B2 (de)
CA (1) CA1243300A (de)
DE (1) DE3261678D1 (de)
IL (1) IL65535A (de)
ZA (1) ZA822662B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816438A (en) * 1984-08-31 1989-03-28 The Salk Institute For Biological Studies Insulin-selective somatostatin analogs
US4880778A (en) * 1986-05-12 1989-11-14 Eastman Kodak Company Combinations having synergistic growth hormone releasing activity and methods for use thereof
US4839344A (en) * 1987-06-12 1989-06-13 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
WO1989007110A1 (en) * 1988-01-28 1989-08-10 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
ES2399651T3 (es) * 2008-07-08 2013-04-02 Novartis Ag Utilización de pasireotida para el tratamiento de la hipoglucemia hiperinsulenémica endógena

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998795A (en) * 1975-06-23 1976-12-21 American Home Products Corporation (Acyl-D-α-amino acid-gly-gly-tyr-ala)1 -somatostatin
US4372884A (en) 1975-08-06 1983-02-08 The Salk Institute For Biological Studies Pharmaceutically active peptides
CA1040624A (en) * 1975-08-28 1978-10-17 Hans U. Immer Extended chain derivatives of somatostatin and process therefor
US4316891A (en) * 1980-06-14 1982-02-23 The Salk Institute For Biological Studies Extended N-terminal somatostatin

Also Published As

Publication number Publication date
ZA822662B (en) 1983-02-23
US4393050A (en) 1983-07-12
CA1243300A (en) 1988-10-18
AU8297482A (en) 1982-11-04
IL65535A (en) 1985-02-28
AU547379B2 (en) 1985-10-17
DE3261678D1 (en) 1985-02-07
EP0063885A1 (de) 1982-11-03
EP0063885B1 (de) 1984-12-27
IL65535A0 (en) 1982-07-30

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