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Abbott Japan Co Ltd
Original Assignee
Hokuriku Pharmaceutical Co Ltd
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Filing date
Publication date
Application filed by Hokuriku Pharmaceutical Co LtdfiledCriticalHokuriku Pharmaceutical Co Ltd
Priority to JP8469981ApriorityCriticalpatent/JPS57200370A/en
Publication of JPS57200370ApublicationCriticalpatent/JPS57200370A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
NEW MATERIAL:A 1-acyl group substituted-4-hydroxyalkylhomopiperazine derivative expressed by formulaI(R is 2,3,4-trimethoxyphenyl or 3,4,5-trimethoxylphenyl; m is 0 or 1; n is 2 or 3) and an acid addition salt thereof.
USE: A vasodilator having improved drug effect on cerebral, peripheral and coronary blood vessels.
PROCESS: A hydroxyalkylhomopiperazine derivative expressed by formula II is reacted with an acyl halogenide expressed by formula III (X is halogen, particularly chloro or bormo) in the presence of a tertiary amine to give the compound expressed by formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP8469981A1981-06-011981-06-011-acyl group substituted-4-hydroxyalkylhomopiperazine derivative
PendingJPS57200370A
(en)
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