JPS57203082A - Manufacture of substituted-4-oxo-4h-1- benzopyran-2-carboxylic acids - Google Patents

Manufacture of substituted-4-oxo-4h-1- benzopyran-2-carboxylic acids

Info

Publication number
JPS57203082A
JPS57203082A JP57057413A JP5741382A JPS57203082A JP S57203082 A JPS57203082 A JP S57203082A JP 57057413 A JP57057413 A JP 57057413A JP 5741382 A JP5741382 A JP 5741382A JP S57203082 A JPS57203082 A JP S57203082A
Authority
JP
Japan
Prior art keywords
benzopyran
oxo
substituted
manufacture
carboxylic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57057413A
Other languages
English (en)
Inventor
Oogusuten Yoahimu
Kaataa Deebitsudo
Burian Rii Toomasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of JPS57203082A publication Critical patent/JPS57203082A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/26—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
    • C07D303/26—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds having one or more free hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP57057413A 1971-07-29 1982-04-08 Manufacture of substituted-4-oxo-4h-1- benzopyran-2-carboxylic acids Pending JPS57203082A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3560571A GB1384530A (en) 1971-07-29 1971-07-29 Chromone derivatives

Publications (1)

Publication Number Publication Date
JPS57203082A true JPS57203082A (en) 1982-12-13

Family

ID=10379579

Family Applications (3)

Application Number Title Priority Date Filing Date
JP47075574A Pending JPS5741476B1 (ja) 1971-07-29 1972-07-29
JP4853481A Granted JPS56158777A (en) 1971-07-29 1981-04-02 Manufacture of substituted-4oxo-4h-1-benzopyrane- 2-carboxylic acids
JP57057413A Pending JPS57203082A (en) 1971-07-29 1982-04-08 Manufacture of substituted-4-oxo-4h-1- benzopyran-2-carboxylic acids

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP47075574A Pending JPS5741476B1 (ja) 1971-07-29 1972-07-29
JP4853481A Granted JPS56158777A (en) 1971-07-29 1981-04-02 Manufacture of substituted-4oxo-4h-1-benzopyrane- 2-carboxylic acids

Country Status (11)

Country Link
US (1) US3882148A (ja)
JP (3) JPS5741476B1 (ja)
CA (1) CA984846A (ja)
CH (8) CH581126A5 (ja)
DE (1) DE2237100A1 (ja)
DK (1) DK133751B (ja)
FR (1) FR2147287B1 (ja)
GB (1) GB1384530A (ja)
IL (1) IL40014A (ja)
NL (1) NL7210478A (ja)
SE (1) SE385891B (ja)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1428186A (en) * 1972-06-21 1976-03-17 Fujisawa Pharmaceutical Co Chromone derivatives
GB1399647A (en) * 1972-12-15 1975-07-02 Fisons Ltd Phenoxyalkoxy-chromone derivatives processes for their preparation and compositions containing them
US4115567A (en) * 1973-12-27 1978-09-19 Carlo Erba S. P. A. 6-Carboxy-2-(2'-pyrazinyl)-chromones and esters thereof
US4065467A (en) * 1973-12-27 1977-12-27 Carlo Erba, S. P. A. 5:6-Benzo δ-pyrone derivatives and process for their preparation
US4148900A (en) * 1973-12-27 1979-04-10 Carlo Erba S.P.A. 5:6-Benzo-γ-pyrone derivatives and process for their preparation
US4238495A (en) * 1976-01-30 1980-12-09 Miles Laboratories, Inc. 1-(4-Cyano-phenoxy)-2-hydroxy-3-[2-(5-1H-tetrazolyl)-chromon-5-yloxy]-propane and salts thereof
SE7800809L (sv) * 1977-01-26 1978-07-27 Fisons Ltd Forfarande for framstellning av nya salter av bensopyranderivat
US4174402A (en) * 1978-08-17 1979-11-13 Sterling Drug Inc. Method for the prophylaxis of SRS-A-induced symptoms
US4252818A (en) * 1979-08-02 1981-02-24 Merck & Co., Inc. Novel benzopyran derivatives
US4311645A (en) * 1980-03-24 1982-01-19 Hoffmann-La Roche Inc. Synthesis of SRS-active compounds
US4315935A (en) * 1980-04-14 1982-02-16 Smithkline Corporation N,N'-Bis[substituted-1,2,3,4-tetrahydroisoquinolinolyl]disulfonylimides and antiallergic compositions and method of use
US4317826A (en) * 1980-05-27 1982-03-02 Smithkline Corporation N,N'-Bis[substituted-1,2,3,4 tetrahydroisoquinolyl]disulfonylimides and antiallergic compositions and method of use
US4321254A (en) * 1980-09-26 1982-03-23 Smithkline Corporation Antiallergic imidodisulfamides
US4385047A (en) * 1981-01-05 1983-05-24 Smithkline Beckman Corporation Antiallergic imidodisulfamides
EP0056172B1 (en) * 1981-01-09 1985-04-03 FISONS plc Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them
DE3265715D1 (en) * 1981-03-24 1985-10-03 Fisons Plc Anti srs-a carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them
US4474788A (en) * 1981-11-12 1984-10-02 Fisons Plc Anti-SRSA quinoline carboxylic acid derivatives
US5135940A (en) * 1982-09-23 1992-08-04 Merck Frosst Canada, Inc. Leukotriene antagonists
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
US4539419A (en) * 1983-05-02 1985-09-03 Hoffmann-La Roche Inc. Naphthalenyloxy substituted carboxylic acids
ZA844519B (en) * 1983-06-24 1985-02-27 Hoffmann La Roche Dihydrobenzopyran derivatives
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
EP0156233A3 (en) * 1984-03-19 1986-02-19 Merck & Co. Inc. Use of leukotriene antagonists for producing cytoprotective pharmaceutical compositions and process for producing cytoprotective pharmaceutical compositions
US4546194A (en) * 1984-05-29 1985-10-08 G. D. Searle & Co. Substituted chromanon-2-yl alkanols and derivatives thereof
JPS6141466U (ja) * 1984-08-09 1986-03-17 健三 杉本 ア−ク溶接用電極棒送給装置
WO1986003742A1 (fr) * 1984-12-26 1986-07-03 Takeda Chemical Industries, Ltd. Procede de preparation de derives d'acide benzoique
JPS61186368A (ja) * 1985-02-14 1986-08-20 Kyorin Pharmaceut Co Ltd 新規な抗アレルギ−薬およびその製造方法
US4889871A (en) * 1987-05-29 1989-12-26 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives
US5093353A (en) * 1988-05-20 1992-03-03 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US5219883A (en) * 1988-05-20 1993-06-15 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US4950684A (en) * 1988-05-20 1990-08-21 G. D. Searle & Co. 2,2-di-substituted benzopyran leukotriene-D4 antagonists
US5212198A (en) * 1990-05-10 1993-05-18 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof
US5192782A (en) * 1990-05-10 1993-03-09 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof
US5073562A (en) * 1990-05-10 1991-12-17 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof
US5124350A (en) * 1990-06-28 1992-06-23 G. D. Searle & Co. Leukotriene b4 antagonists
PH30449A (en) * 1991-11-25 1997-05-28 Lilly Co Eli Substituted phenyl phenol leukotriene antagonists
US5352690A (en) * 1992-07-01 1994-10-04 Eli Lilly And Company 1,2,4-trioxygenated benzene derivatives useful as leukotriene antagonists
US5380740A (en) * 1993-04-28 1995-01-10 G. D. Searle & Co. Anti-inflammatory compounds, compositions and method of use thereof
WO2014030688A1 (ja) * 2012-08-24 2014-02-27 第一三共株式会社 鎖状側鎖を有するクロモン誘導体
CN107216354B (zh) * 2017-07-04 2019-10-18 西北工业大学 基于环三磷腈的六官能度环氧树脂的制备方法
CN113236746B (zh) * 2021-04-08 2024-08-30 浙江万里扬股份有限公司 变速器和车辆

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1144905A (en) * 1965-03-25 1969-03-12 Fisons Pharmaceuticals Ltd Substituted bis-(2-carboxy-chromonyl-oxy) derivatives and preparation and pharmaceutical compositions thereof
GB1190194A (en) * 1966-07-05 1970-04-29 Fisons Pharmaceuticals Ltd Bis-Phenoxy Compounds and Chromanone and Chromone Derivatives
GB1292601A (en) * 1968-10-30 1972-10-11 Fisons Pharmaceuticals Ltd Bis-(2-carboxy-chromone) compounds, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPS5741476B1 (ja) 1982-09-03
CH565784A5 (ja) 1975-08-29
IL40014A (en) 1976-05-31
CH564553A5 (ja) 1975-07-31
CH565170A5 (ja) 1975-08-15
JPS56158777A (en) 1981-12-07
CH565785A5 (ja) 1975-08-29
GB1384530A (en) 1975-02-19
JPS5744677B2 (ja) 1982-09-22
CH564549A5 (ja) 1975-07-31
DK133751C (ja) 1976-11-29
NL7210478A (ja) 1973-01-31
FR2147287A1 (ja) 1973-03-09
CH581126A5 (ja) 1976-10-29
DK133751B (da) 1976-07-12
FR2147287B1 (ja) 1976-04-16
DE2237100A1 (de) 1973-02-08
CH567498A5 (ja) 1975-10-15
CH565783A5 (ja) 1975-08-29
CA984846A (en) 1976-03-02
SE385891B (sv) 1976-07-26
US3882148A (en) 1975-05-06
IL40014A0 (en) 1972-09-28

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