JPS5729951A - Determintion of sugar side chain related to cancer - Google Patents

Determintion of sugar side chain related to cancer

Info

Publication number
JPS5729951A
JPS5729951A JP10478880A JP10478880A JPS5729951A JP S5729951 A JPS5729951 A JP S5729951A JP 10478880 A JP10478880 A JP 10478880A JP 10478880 A JP10478880 A JP 10478880A JP S5729951 A JPS5729951 A JP S5729951A
Authority
JP
Japan
Prior art keywords
lectin
cancer
side chain
sugar side
tag
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10478880A
Other languages
Japanese (ja)
Inventor
Shoichi Adachi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIPPON KOUTAI KENKYUSHO KK
Original Assignee
NIPPON KOUTAI KENKYUSHO KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIPPON KOUTAI KENKYUSHO KK filed Critical NIPPON KOUTAI KENKYUSHO KK
Priority to JP10478880A priority Critical patent/JPS5729951A/en
Publication of JPS5729951A publication Critical patent/JPS5729951A/en
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PURPOSE:To quantitate sugar side chain related to cancer and to diagonse accurately various cancers by reacting a sugar side chain related to cancer in body fluids with lectin which is capable of forming a complex with N-acetyl-D-galactosamine, and measuring an amount of the complex formed, or the residual lectin. CONSTITUTION:A sugar side chain (shortly expressed as TAG hereafter) related to cancer which is produced by cancer cells in body liquids is separated from body liquids, and reacted with lectin which has ability to form a complex with N-acetyl- D-galatosamine(expressed as AG hereafter), then an amount of the TAG-lectin complex or the residual lectin is measured. Otherwise a labeled lectin is added to a body liquid itself and reacted with it, and the TAG-labeled lectin or the residual labeled lectin is separated, then TAG in the body liquid is quantitated by measuring either amount of them.
JP10478880A 1980-07-30 1980-07-30 Determintion of sugar side chain related to cancer Pending JPS5729951A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10478880A JPS5729951A (en) 1980-07-30 1980-07-30 Determintion of sugar side chain related to cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10478880A JPS5729951A (en) 1980-07-30 1980-07-30 Determintion of sugar side chain related to cancer

Publications (1)

Publication Number Publication Date
JPS5729951A true JPS5729951A (en) 1982-02-18

Family

ID=14390194

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10478880A Pending JPS5729951A (en) 1980-07-30 1980-07-30 Determintion of sugar side chain related to cancer

Country Status (1)

Country Link
JP (1) JPS5729951A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2520877A1 (en) * 1982-01-29 1983-08-05 Otsuka Pharma Co Ltd Specific binding assay for tumour-associated glyco:linkage - using lectin capable of binding N-acetyl-D-galactosamine or L-fucose
WO1984000421A1 (en) * 1982-07-16 1984-02-02 Otsuka Pharma Co Ltd Method for assaying tumor-associated antigen-specific immune complex
US4455380A (en) * 1982-01-29 1984-06-19 Otsuka Pharmaceutical Co., Ltd. Process for determining tumor-associated glycolinkage
WO1985001442A1 (en) * 1983-09-28 1985-04-11 Summa Medical Corporation Lectin composition and method for diagnosis of cancer
JPH03140865A (en) * 1989-10-27 1991-06-14 Kosumitsuku:Kk How to identify malignant tumors
WO2002077649A1 (en) * 2001-03-27 2002-10-03 Teikoku Hormone Mfg. Co., Ltd. Method of diagnosing breast cancer

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS549435A (en) * 1977-06-22 1979-01-24 Manabu Ooba Floodgate
JPS54141741A (en) * 1978-04-21 1979-11-05 Basf Ag Manufacture of aromatic and araliphatic aldehyde
JPS5557584A (en) * 1978-10-25 1980-04-28 Japan Tobacco Inc Preparation of 1'-methyl-2'-(3-pyridyl)-2'-pyrroline
JPS55102082A (en) * 1979-01-31 1980-08-04 Nec Corp Hammer magnet drive circuit

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS549435A (en) * 1977-06-22 1979-01-24 Manabu Ooba Floodgate
JPS54141741A (en) * 1978-04-21 1979-11-05 Basf Ag Manufacture of aromatic and araliphatic aldehyde
JPS5557584A (en) * 1978-10-25 1980-04-28 Japan Tobacco Inc Preparation of 1'-methyl-2'-(3-pyridyl)-2'-pyrroline
JPS55102082A (en) * 1979-01-31 1980-08-04 Nec Corp Hammer magnet drive circuit

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2520877A1 (en) * 1982-01-29 1983-08-05 Otsuka Pharma Co Ltd Specific binding assay for tumour-associated glyco:linkage - using lectin capable of binding N-acetyl-D-galactosamine or L-fucose
US4455380A (en) * 1982-01-29 1984-06-19 Otsuka Pharmaceutical Co., Ltd. Process for determining tumor-associated glycolinkage
WO1984000421A1 (en) * 1982-07-16 1984-02-02 Otsuka Pharma Co Ltd Method for assaying tumor-associated antigen-specific immune complex
WO1985001442A1 (en) * 1983-09-28 1985-04-11 Summa Medical Corporation Lectin composition and method for diagnosis of cancer
JPH03140865A (en) * 1989-10-27 1991-06-14 Kosumitsuku:Kk How to identify malignant tumors
WO2002077649A1 (en) * 2001-03-27 2002-10-03 Teikoku Hormone Mfg. Co., Ltd. Method of diagnosing breast cancer

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