JPS5735521A - Fractionation of plasma protein - Google Patents

Fractionation of plasma protein

Info

Publication number
JPS5735521A
JPS5735521A JP11029580A JP11029580A JPS5735521A JP S5735521 A JPS5735521 A JP S5735521A JP 11029580 A JP11029580 A JP 11029580A JP 11029580 A JP11029580 A JP 11029580A JP S5735521 A JPS5735521 A JP S5735521A
Authority
JP
Japan
Prior art keywords
plasma protein
substance
aqueous solution
solution containing
zinc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11029580A
Other languages
Japanese (ja)
Other versions
JPS6236486B2 (en
Inventor
Takeshi Takahashi
Kazuo Takechi
Eiichi Hasegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
GC Biopharma Corp
Original Assignee
Green Cross Corp Japan
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Green Cross Corp Korea filed Critical Green Cross Corp Japan
Priority to JP11029580A priority Critical patent/JPS5735521A/en
Publication of JPS5735521A publication Critical patent/JPS5735521A/en
Publication of JPS6236486B2 publication Critical patent/JPS6236486B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PURPOSE: To leave a mold substance and exothermic substance in a supernatant liquid and to remove these substance from an aqueous solution containing plasma protein, by adding an aluminum salt and zinc salt to an aqueous solution containing human albumin and/or γ-globulin, so that plasma protein is precipitated.
CONSTITUTION: An aluminum salt (e.g., alum, aluminum sulfate, etc.) in an amount to make the final concentration 0.05W10mM and a zinc salt (e.g., zinc acetate, zinc sulfate, etc.) in an amount to give the final concentration 0.5W100mM are added to an aqueous solution containing human albumin and/or γ-globulin (e.g., human blood, serum, the placenta, etc.), so that plasma protein is precipitated. Simultaneously, a mold substance and exothermic substance admixed in it are left in the supernatant liquid, so that these substances are removed from human plasma protein economically by a safe method completely. The reaction temperature is 0W35°C, preferably 4W25°C.
COPYRIGHT: (C)1982,JPO&Japio
JP11029580A 1980-08-13 1980-08-13 Fractionation of plasma protein Granted JPS5735521A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11029580A JPS5735521A (en) 1980-08-13 1980-08-13 Fractionation of plasma protein

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11029580A JPS5735521A (en) 1980-08-13 1980-08-13 Fractionation of plasma protein

Publications (2)

Publication Number Publication Date
JPS5735521A true JPS5735521A (en) 1982-02-26
JPS6236486B2 JPS6236486B2 (en) 1987-08-07

Family

ID=14532069

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11029580A Granted JPS5735521A (en) 1980-08-13 1980-08-13 Fractionation of plasma protein

Country Status (1)

Country Link
JP (1) JPS5735521A (en)

Also Published As

Publication number Publication date
JPS6236486B2 (en) 1987-08-07

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