JPS574992A - Trioxaspiro ring compound - Google Patents

Trioxaspiro ring compound

Info

Publication number
JPS574992A
JPS574992A JP7850080A JP7850080A JPS574992A JP S574992 A JPS574992 A JP S574992A JP 7850080 A JP7850080 A JP 7850080A JP 7850080 A JP7850080 A JP 7850080A JP S574992 A JPS574992 A JP S574992A
Authority
JP
Japan
Prior art keywords
formula
compound shown
trioxaspiro
give
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7850080A
Other languages
Japanese (ja)
Inventor
Akira Terahara
Hidehiko Oka
Toshiharu Kamioka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP7850080A priority Critical patent/JPS574992A/en
Publication of JPS574992A publication Critical patent/JPS574992A/en
Pending legal-status Critical Current

Links

Landscapes

  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A trioxaspiro ring compound shown by the formula I (X is halogen; R1 and R2 are H or 1W4C alkyl; n is 2 or 3).
EXAMPLE: 9- [1- (4-Chlorophenoxy )-1-methylethyl ]-1,4,8-trioxaspiro [4,5]decane- 7-one.
USE: A drug having antianxiety action. The titled compound together with a carrier material, diluent, etc. is pharmaceutically manufactured into tablets, capsules, etc., which are administered orally. A dose per adult is about 50W150mg/day, preferably 100W150mg/day.
PROCESS: According to the reaction formulas, a compound shown by the formula II is converted into a compound shown by the formula III, which is reacted with a novel compound shown by the formula IV, to give a compound shown by the formula V. This compound is then hydrolyzed in alkali state, and subjected to ring closure in the presence of an acid catalyst, to give a compound shown by the formula VI. The carbonyl group is changed into a ketal, to give a compound shown by the formula I.
COPYRIGHT: (C)1982,JPO&Japio
JP7850080A 1980-06-11 1980-06-11 Trioxaspiro ring compound Pending JPS574992A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7850080A JPS574992A (en) 1980-06-11 1980-06-11 Trioxaspiro ring compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7850080A JPS574992A (en) 1980-06-11 1980-06-11 Trioxaspiro ring compound

Publications (1)

Publication Number Publication Date
JPS574992A true JPS574992A (en) 1982-01-11

Family

ID=13663675

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7850080A Pending JPS574992A (en) 1980-06-11 1980-06-11 Trioxaspiro ring compound

Country Status (1)

Country Link
JP (1) JPS574992A (en)

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