JPS5753232A - Preparation of microcapsule - Google Patents

Preparation of microcapsule

Info

Publication number
JPS5753232A
JPS5753232A JP55127236A JP12723680A JPS5753232A JP S5753232 A JPS5753232 A JP S5753232A JP 55127236 A JP55127236 A JP 55127236A JP 12723680 A JP12723680 A JP 12723680A JP S5753232 A JPS5753232 A JP S5753232A
Authority
JP
Japan
Prior art keywords
casein
microcapsule
substance
para
dispersed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55127236A
Other languages
Japanese (ja)
Other versions
JPS6020059B2 (en
Inventor
Hiroshi Niki
Seiichiro Igarashi
Masayuki Arakawa
Tamotsu Kondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Snow Brand Milk Products Co Ltd
Original Assignee
Snow Brand Milk Products Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snow Brand Milk Products Co Ltd filed Critical Snow Brand Milk Products Co Ltd
Priority to JP12723680A priority Critical patent/JPS6020059B2/en
Publication of JPS5753232A publication Critical patent/JPS5753232A/en
Publication of JPS6020059B2 publication Critical patent/JPS6020059B2/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/10—Complex coacervation, i.e. interaction of oppositely charged particles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

PURPOSE: To obtain a microcapsule for a food and a drug containing casein as a wall film substance by a method wherein a solid or oils or fats hardly soluble in water is dispersed in an aqueous casein solution and milk coagulating enzyme is added thereto to coagulate the casein around a dispersed substance as para-casein and the resultant microcapsule is warmed. CONSTITUTION:A solid or oils or fats hardly soluble in water is dispersed in an aqueous solution containing casein as a core substance in an amount of about 0.5- 5%. To the resultant dispersion, a mild coagulating enzyme such as calf rennet, bacterial rennet, pepsin, trypsin, papain or the like is added in an amount of about 0.001-0.01mol and, thereby, casein is coagulated around the core substance as para-casein. When the resultant dispersion is slowly warmed to a temp. of 35- 45 deg.C, para-casein is fixed to form a microcapsule. Further, prior to acting the milk coagulating enzyme, casein may be gathered to a periphery of the core substance by coacervation or difference of solubility.
JP12723680A 1980-09-16 1980-09-16 Method for producing microcapsules suitable for food or medicine Expired JPS6020059B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12723680A JPS6020059B2 (en) 1980-09-16 1980-09-16 Method for producing microcapsules suitable for food or medicine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12723680A JPS6020059B2 (en) 1980-09-16 1980-09-16 Method for producing microcapsules suitable for food or medicine

Publications (2)

Publication Number Publication Date
JPS5753232A true JPS5753232A (en) 1982-03-30
JPS6020059B2 JPS6020059B2 (en) 1985-05-20

Family

ID=14955075

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12723680A Expired JPS6020059B2 (en) 1980-09-16 1980-09-16 Method for producing microcapsules suitable for food or medicine

Country Status (1)

Country Link
JP (1) JPS6020059B2 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
CN1056056C (en) * 1994-12-05 2000-09-06 上海第二医科大学附属仁济医院 Enteric solubility bacterial enzyme composite bed microcapsule preparation and its preparing method
EP0938299A4 (en) * 1996-08-19 2001-01-17 Vivorx Pharmaceuticals Inc Methods for the production of protein particles useful for delivery of pharmacological agents
EP1683517A1 (en) * 1996-08-19 2006-07-26 American Bioscience, Inc. Methods for the production of protein particles useful for delivery of pharmacological agents
NL1028383C2 (en) * 2005-02-23 2006-08-24 Friesland Brands Bv Microcapsules.
JP2017210415A (en) * 2016-05-24 2017-11-30 三生医薬株式会社 Oral pharmaceutical composition and method for producing particulate formulation comprising composition the same

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0223562A (en) * 1988-07-12 1990-01-25 Hitachi Ltd Automatic tape magazine

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
CN1056056C (en) * 1994-12-05 2000-09-06 上海第二医科大学附属仁济医院 Enteric solubility bacterial enzyme composite bed microcapsule preparation and its preparing method
EP0938299A4 (en) * 1996-08-19 2001-01-17 Vivorx Pharmaceuticals Inc Methods for the production of protein particles useful for delivery of pharmacological agents
EP1683517A1 (en) * 1996-08-19 2006-07-26 American Bioscience, Inc. Methods for the production of protein particles useful for delivery of pharmacological agents
NL1028383C2 (en) * 2005-02-23 2006-08-24 Friesland Brands Bv Microcapsules.
WO2006091081A1 (en) * 2005-02-23 2006-08-31 Friesland Brands B.V. Microcapsules
JP2017210415A (en) * 2016-05-24 2017-11-30 三生医薬株式会社 Oral pharmaceutical composition and method for producing particulate formulation comprising composition the same
WO2017204210A1 (en) * 2016-05-24 2017-11-30 三生医薬株式会社 Oral pharmaceutical composition and method for producing particulate formulation comprising composition

Also Published As

Publication number Publication date
JPS6020059B2 (en) 1985-05-20

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