JPS577405A - Whitening cosmetic - Google Patents
Whitening cosmeticInfo
- Publication number
- JPS577405A JPS577405A JP8164580A JP8164580A JPS577405A JP S577405 A JPS577405 A JP S577405A JP 8164580 A JP8164580 A JP 8164580A JP 8164580 A JP8164580 A JP 8164580A JP S577405 A JPS577405 A JP S577405A
- Authority
- JP
- Japan
- Prior art keywords
- pantetheine
- cosmetic
- acyl
- derivative
- whitening cosmetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002537 cosmetic Substances 0.000 title abstract 8
- 230000002087 whitening effect Effects 0.000 title abstract 3
- ZNXZGRMVNNHPCA-UHFFFAOYSA-N Pantetheine Natural products OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS ZNXZGRMVNNHPCA-UHFFFAOYSA-N 0.000 abstract 5
- ZNXZGRMVNNHPCA-VIFPVBQESA-N pantetheine Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCS ZNXZGRMVNNHPCA-VIFPVBQESA-N 0.000 abstract 4
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 102000003425 Tyrosinase Human genes 0.000 abstract 1
- 108060008724 Tyrosinase Proteins 0.000 abstract 1
- -1 acryl group Chemical group 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 230000001976 improved effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
PURPOSE:A whitening cosmetic having inhibiting actions on tyrosinase activity and decoloring actions on melanin dyestuff, exhibiting improved effect, capable of being used safely, obtained by adding pantetheine or its derivative to a cosmetic base. CONSTITUTION:A whitening cosmetic obtained by adding pantetheine and or its derivative to a cosmetic base. Especially a pantetheine acyl derivative shown by the formula (all R1-R3 are not H, at least one is straight-chain or branched chain acyl and the others are H) is preferable, and an acryl group is properly selected from 2-20C acyl groups corresponding to the types of cosmetics. For example, in the case of water-soluble cosmetic, 2-6C acyl group (e.g., S-monobutanoyl pantetheine, etc.) is used, and in the case of oil-soluble cosmetic, 8-20C acyl group (e.g., S,O-dilauroyl pantetheine, etc.) is used.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8164580A JPS577405A (en) | 1980-06-17 | 1980-06-17 | Whitening cosmetic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8164580A JPS577405A (en) | 1980-06-17 | 1980-06-17 | Whitening cosmetic |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS577405A true JPS577405A (en) | 1982-01-14 |
| JPH0114202B2 JPH0114202B2 (en) | 1989-03-10 |
Family
ID=13752070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8164580A Granted JPS577405A (en) | 1980-06-17 | 1980-06-17 | Whitening cosmetic |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS577405A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6064922A (en) * | 1983-09-21 | 1985-04-13 | Sogo Yatsukou Kk | Dermatic drug for external application |
| JPH07238010A (en) * | 1994-02-24 | 1995-09-12 | Kanebo Ltd | Skin cosmetic |
| JP2022520518A (en) * | 2018-11-30 | 2022-03-31 | コメット セラピューティクス インコーポレイテッド | Pantetheine derivatives and their use |
-
1980
- 1980-06-17 JP JP8164580A patent/JPS577405A/en active Granted
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6064922A (en) * | 1983-09-21 | 1985-04-13 | Sogo Yatsukou Kk | Dermatic drug for external application |
| JPH07238010A (en) * | 1994-02-24 | 1995-09-12 | Kanebo Ltd | Skin cosmetic |
| JP2022520518A (en) * | 2018-11-30 | 2022-03-31 | コメット セラピューティクス インコーポレイテッド | Pantetheine derivatives and their use |
| JP2025011095A (en) * | 2018-11-30 | 2025-01-23 | コメット セラピューティクス インコーポレイテッド | Pantetheine derivatives and uses thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0114202B2 (en) | 1989-03-10 |
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