JPS577423A - Frozen or freeze-dried live measles vaccine - Google Patents

Frozen or freeze-dried live measles vaccine

Info

Publication number
JPS577423A
JPS577423A JP8046580A JP8046580A JPS577423A JP S577423 A JPS577423 A JP S577423A JP 8046580 A JP8046580 A JP 8046580A JP 8046580 A JP8046580 A JP 8046580A JP S577423 A JPS577423 A JP S577423A
Authority
JP
Japan
Prior art keywords
vaccine
live measles
frozen
freeze
measles vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8046580A
Other languages
Japanese (ja)
Other versions
JPH0133449B2 (en
Inventor
Seijiro Sasai
Kennosuke Ichiki
Kouji Terakouchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP8046580A priority Critical patent/JPS577423A/en
Publication of JPS577423A publication Critical patent/JPS577423A/en
Publication of JPH0133449B2 publication Critical patent/JPH0133449B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PURPOSE: To prepare the titled vaccine capable of keeping stable titer for a long period, by adding a sugar alcohol and a sugar to a live measles vaccine.
CONSTITUTION: Live measles vaccine containing a sugar alcohol and a sugar (e.g. D-sorbitol and lactose) and if necessary, human serum albumin, dextran, and gelatin. The live measles vaccine is a vaccine composed mainly of attenuated live measles viruses, and is ususlly frozen or freeze-dried for the purpose of storage. The titer (infection titer) of the vaccine tends to decrease during the preparation and storage; however, the addition of the above additives to the stock solution of the live measles vaccine remarkably stabilizes the frozen or freeze-dried product to ensure the long-term storage.
COPYRIGHT: (C)1982,JPO&Japio
JP8046580A 1980-06-13 1980-06-13 Frozen or freeze-dried live measles vaccine Granted JPS577423A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8046580A JPS577423A (en) 1980-06-13 1980-06-13 Frozen or freeze-dried live measles vaccine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8046580A JPS577423A (en) 1980-06-13 1980-06-13 Frozen or freeze-dried live measles vaccine

Publications (2)

Publication Number Publication Date
JPS577423A true JPS577423A (en) 1982-01-14
JPH0133449B2 JPH0133449B2 (en) 1989-07-13

Family

ID=13719000

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8046580A Granted JPS577423A (en) 1980-06-13 1980-06-13 Frozen or freeze-dried live measles vaccine

Country Status (1)

Country Link
JP (1) JPS577423A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5997136A (en) * 1982-11-26 1984-06-04 Fuji Photo Film Co Ltd Photosensitive composition
JPS59222834A (en) * 1983-06-01 1984-12-14 Fuji Photo Film Co Ltd Photosensitive composition
FR2742756A1 (en) * 1995-12-22 1997-06-27 Pasteur Merieux Serums Vacc STABILIZERS FOR LIVE VACCINES, VACCINES CONTAINING SAME, AND PROCESSES FOR THEIR PREPARATION
WO1998028000A1 (en) * 1996-12-20 1998-07-02 Merck & Co., Inc. Stabilizers for lyophilized vaccines
WO1999012568A1 (en) * 1997-09-05 1999-03-18 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
WO1999062500A1 (en) * 1998-06-03 1999-12-09 Merck & Co., Inc. Stabilizers for lyophilized vaccines
US6051238A (en) * 1996-12-20 2000-04-18 Merck & Co., Inc. Stabilizers for lyophilized mumps vaccines
CN112023057A (en) * 2020-10-21 2020-12-04 成都柏奥特克生物科技股份有限公司 Vaccine protective agent
US12364723B2 (en) 2018-12-27 2025-07-22 Amgen Inc. Thermostable compositions comprising live attenuated herpes simplex virus type 1

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49109520A (en) * 1973-02-07 1974-10-18

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49109520A (en) * 1973-02-07 1974-10-18

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5997136A (en) * 1982-11-26 1984-06-04 Fuji Photo Film Co Ltd Photosensitive composition
JPS59222834A (en) * 1983-06-01 1984-12-14 Fuji Photo Film Co Ltd Photosensitive composition
FR2742756A1 (en) * 1995-12-22 1997-06-27 Pasteur Merieux Serums Vacc STABILIZERS FOR LIVE VACCINES, VACCINES CONTAINING SAME, AND PROCESSES FOR THEIR PREPARATION
WO1997023238A1 (en) * 1995-12-22 1997-07-03 Pasteur Merieux Serums & Vaccins Stabilisers for live vaccines
US6231860B1 (en) 1995-12-22 2001-05-15 Pasteur Merieux Serums & Vaccins Stabilizers for live vaccines
WO1998028000A1 (en) * 1996-12-20 1998-07-02 Merck & Co., Inc. Stabilizers for lyophilized vaccines
US6051238A (en) * 1996-12-20 2000-04-18 Merck & Co., Inc. Stabilizers for lyophilized mumps vaccines
WO1999012568A1 (en) * 1997-09-05 1999-03-18 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
US6210683B1 (en) 1997-09-05 2001-04-03 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
WO1999062500A1 (en) * 1998-06-03 1999-12-09 Merck & Co., Inc. Stabilizers for lyophilized vaccines
US12364723B2 (en) 2018-12-27 2025-07-22 Amgen Inc. Thermostable compositions comprising live attenuated herpes simplex virus type 1
CN112023057A (en) * 2020-10-21 2020-12-04 成都柏奥特克生物科技股份有限公司 Vaccine protective agent

Also Published As

Publication number Publication date
JPH0133449B2 (en) 1989-07-13

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