JPS5775962A - 2-alkoxybenzamide derivative - Google Patents
2-alkoxybenzamide derivativeInfo
- Publication number
- JPS5775962A JPS5775962A JP15255180A JP15255180A JPS5775962A JP S5775962 A JPS5775962 A JP S5775962A JP 15255180 A JP15255180 A JP 15255180A JP 15255180 A JP15255180 A JP 15255180A JP S5775962 A JPS5775962 A JP S5775962A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound shown
- formulai
- formula
- alkoxybenzamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- -1 nitro, amino Chemical group 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 230000001079 digestive effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
Landscapes
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A compound shown by the formulaI(R1 is alkyl; R2 and R4 are H or alkyl; R3 alkanyl, nitro, amino, etc.; R5 is alkyl, 1-alkyl-4-piperidinyl, etc.).
EXAMPLE: 1-(5-Acetyl-2-methoxy-3-methylbenzoyl)-4-methylpiperazine.
USE: An improver for acatastasia of digestive function. Having promoting action on the elimination of content in the stomach, and low side effects of its center.
PROCESS: A compound shown by the formula II (X is hydroxyl group, etc.) is reacted with an amine shown by the formula R4-NH-R5 in an inert solvent (e.g., acetone, etc.) at room temperature or under cooling or heating, usually at -20W150°C, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15255180A JPS5775962A (en) | 1980-10-29 | 1980-10-29 | 2-alkoxybenzamide derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15255180A JPS5775962A (en) | 1980-10-29 | 1980-10-29 | 2-alkoxybenzamide derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5775962A true JPS5775962A (en) | 1982-05-12 |
Family
ID=15542930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15255180A Pending JPS5775962A (en) | 1980-10-29 | 1980-10-29 | 2-alkoxybenzamide derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5775962A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7390908B2 (en) | 2001-08-17 | 2008-06-24 | Astrazeneca Ab | Compounds effecting glucokinase |
| US7642263B2 (en) | 2005-07-09 | 2010-01-05 | Astrazeneca Ab | Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes |
| US7696191B2 (en) | 2006-12-21 | 2010-04-13 | Astrazeneca Ab | Crystalline compound |
| US7700640B2 (en) | 2004-10-16 | 2010-04-20 | Astrazeneca Ab | Process for making phenoxy benzamide compounds |
| US7709505B2 (en) | 2002-11-19 | 2010-05-04 | Astrazeneca Ab | Benzofuran derivatives, process for their preparation and intermediates thereof |
| US7902200B2 (en) | 2006-10-23 | 2011-03-08 | Astrazeneca Ab | Chemical compounds |
| US7973178B2 (en) | 2005-11-28 | 2011-07-05 | Astrazeneca Ab | Chemical process for the preparation of an amido-phenoxybenzoic acid compound |
| US8071608B2 (en) | 2009-04-09 | 2011-12-06 | Astrazeneca Ab | Therapeutic agents |
-
1980
- 1980-10-29 JP JP15255180A patent/JPS5775962A/en active Pending
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7390908B2 (en) | 2001-08-17 | 2008-06-24 | Astrazeneca Ab | Compounds effecting glucokinase |
| US7524957B2 (en) | 2001-08-17 | 2009-04-28 | Astrazeneca Ab | Compounds effecting glucokinase |
| US7951830B2 (en) | 2001-08-17 | 2011-05-31 | Astrazeneca Ab | Compounds effecting glucokinase |
| US7709505B2 (en) | 2002-11-19 | 2010-05-04 | Astrazeneca Ab | Benzofuran derivatives, process for their preparation and intermediates thereof |
| US7700640B2 (en) | 2004-10-16 | 2010-04-20 | Astrazeneca Ab | Process for making phenoxy benzamide compounds |
| US7642263B2 (en) | 2005-07-09 | 2010-01-05 | Astrazeneca Ab | Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes |
| US7642259B2 (en) | 2005-07-09 | 2010-01-05 | Astrazeneca Ab | Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes |
| US7977328B2 (en) | 2005-07-09 | 2011-07-12 | Astrazeneca Ab | Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes |
| US7973178B2 (en) | 2005-11-28 | 2011-07-05 | Astrazeneca Ab | Chemical process for the preparation of an amido-phenoxybenzoic acid compound |
| US7902200B2 (en) | 2006-10-23 | 2011-03-08 | Astrazeneca Ab | Chemical compounds |
| US7696191B2 (en) | 2006-12-21 | 2010-04-13 | Astrazeneca Ab | Crystalline compound |
| US8071608B2 (en) | 2009-04-09 | 2011-12-06 | Astrazeneca Ab | Therapeutic agents |
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