JPS5785316A - Preparation of easily absorbable nifedipine preparation - Google Patents

Preparation of easily absorbable nifedipine preparation

Info

Publication number: JPS5785316A
Authority: JP; Japan
Prior art keywords: preparation; water; nifedipine; soluble; dimethyl
Prior art date: 1980-11-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP16095280A

Other languages

English (en)

Japanese (ja)

Other versions

JPH031288B2 (de

Inventor

Kazunori Togo

Atsushi Yamagata

Kozo Sasaki

Isao Sugimoto

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kanebo Ltd

Original Assignee

Kanebo Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-11-14

Filing date

1980-11-14

Publication date

1982-05-28

1980-11-14 Application filed by Kanebo Ltd filed Critical Kanebo Ltd

1980-11-14 Priority to JP16095280A priority Critical patent/JPS5785316A/ja

1982-05-28 Publication of JPS5785316A publication Critical patent/JPS5785316A/ja

1991-01-10 Publication of JPH031288B2 publication Critical patent/JPH031288B2/ja

Status Granted legal-status Critical Current

Links

238000002360 preparation method Methods 0.000 title abstract 5
HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 title abstract 4
229960001597 nifedipine Drugs 0.000 title abstract 4
239000008187 granular material Substances 0.000 abstract 3
239000011248 coating agent Substances 0.000 abstract 2
238000000576 coating method Methods 0.000 abstract 2
239000000546 pharmaceutical excipient Substances 0.000 abstract 2
229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 2
239000001267 polyvinylpyrrolidone Substances 0.000 abstract 2
235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 2
239000006104 solid solution Substances 0.000 abstract 2
GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 1
206010002383 Angina Pectoris Diseases 0.000 abstract 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
239000011230 binding agent Substances 0.000 abstract 1
239000003085 diluting agent Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
230000003179 granulation Effects 0.000 abstract 1
238000005469 granulation Methods 0.000 abstract 1
239000008101 lactose Substances 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Landscapes

Hydrogenated Pyridines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

JP16095280A 1980-11-14 1980-11-14 Preparation of easily absorbable nifedipine preparation Granted JPS5785316A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP16095280A JPS5785316A (en)	1980-11-14	1980-11-14	Preparation of easily absorbable nifedipine preparation

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP16095280A JPS5785316A (en)	1980-11-14	1980-11-14	Preparation of easily absorbable nifedipine preparation

Publications (2)

Publication Number	Publication Date
JPS5785316A true JPS5785316A (en)	1982-05-28
JPH031288B2 JPH031288B2 (de)	1991-01-10

Family

ID=15725741

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP16095280A Granted JPS5785316A (en)	1980-11-14	1980-11-14	Preparation of easily absorbable nifedipine preparation

Country Status (1)

Country	Link
JP (1)	JPS5785316A (de)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1984003440A1 (fr) *	1981-09-14	1984-09-13	Kanebo Ltd	Preparation a base de nifedipine a action prolongee
US4562069A (en) *	1983-05-21	1985-12-31	Bayer Aktiengesellschaft	Two-phase formulation
EP0175671A1 (de) *	1984-08-23	1986-03-26	Kuhlemann & Co.	Pharmazeutische Zubereitung sowie Verfahren zum Darreichen dieser pharmazeutischen Zubereitung
JPS61100528A (ja) *	1984-10-23	1986-05-19	ドクトル　レンチユレル　アルツナイミツテル　ゲ−エムベ−ハ−　ウント　コ−	ニフエジピン含有薬剤組成物とその製造方法
JPH01249718A (ja) *	1988-03-30	1989-10-05	Tomoaki Fukuda	マイクロカプセルの製造方法
US4888177A (en) *	1984-11-05	1989-12-19	Gerhard Gergely	Pharamaceutical preparations in the form of instant granules or tablets and process for their manufacture
JP2527107B2 (ja) *	1991-04-16	1996-08-21	日本新薬株式会社	固体分散体の製造方法
EP1291014A1 (de) *	2001-09-05	2003-03-12	Shin-Etsu Chemical Co., Ltd.	Prozess zur Herstellung einer festen pharmazeutischen Zubereitung welche einen schwerlöslichen Wirkstoff enthält

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4832897B2 (ja)	2003-08-29	2011-12-07	日本たばこ産業株式会社	エステル誘導体及びその医薬用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5283916A (en) *	1976-01-02	1977-07-13	Beecham Group Ltd	Medical composition for aural administration

1980
- 1980-11-14 JP JP16095280A patent/JPS5785316A/ja active Granted

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5283916A (en) *	1976-01-02	1977-07-13	Beecham Group Ltd	Medical composition for aural administration

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1984003440A1 (fr) *	1981-09-14	1984-09-13	Kanebo Ltd	Preparation a base de nifedipine a action prolongee
US4562069A (en) *	1983-05-21	1985-12-31	Bayer Aktiengesellschaft	Two-phase formulation
EP0175671A1 (de) *	1984-08-23	1986-03-26	Kuhlemann & Co.	Pharmazeutische Zubereitung sowie Verfahren zum Darreichen dieser pharmazeutischen Zubereitung
JPS61100528A (ja) *	1984-10-23	1986-05-19	ドクトル　レンチユレル　アルツナイミツテル　ゲ−エムベ−ハ−　ウント　コ−	ニフエジピン含有薬剤組成物とその製造方法
US4888177A (en) *	1984-11-05	1989-12-19	Gerhard Gergely	Pharamaceutical preparations in the form of instant granules or tablets and process for their manufacture
JPH01249718A (ja) *	1988-03-30	1989-10-05	Tomoaki Fukuda	マイクロカプセルの製造方法
JP2527107B2 (ja) *	1991-04-16	1996-08-21	日本新薬株式会社	固体分散体の製造方法
EP1291014A1 (de) *	2001-09-05	2003-03-12	Shin-Etsu Chemical Co., Ltd.	Prozess zur Herstellung einer festen pharmazeutischen Zubereitung welche einen schwerlöslichen Wirkstoff enthält
US6872336B2 (en)	2001-09-05	2005-03-29	Shin-Etsu Chemical Co., Ltd.	Process for producing a pharmaceutical solid preparation containing a poorly soluble drug

Also Published As

Publication number	Publication date
JPH031288B2 (de)	1991-01-10

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