JPS5791993A - Novel antibiotic substance, its preparation and microorganism capable of producing the same - Google Patents

Novel antibiotic substance, its preparation and microorganism capable of producing the same

Info

Publication number
JPS5791993A
JPS5791993A JP16669880A JP16669880A JPS5791993A JP S5791993 A JPS5791993 A JP S5791993A JP 16669880 A JP16669880 A JP 16669880A JP 16669880 A JP16669880 A JP 16669880A JP S5791993 A JPS5791993 A JP S5791993A
Authority
JP
Japan
Prior art keywords
substance
antibiotic
water
antibiotic substance
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP16669880A
Other languages
Japanese (ja)
Inventor
Yukio Miyazaki
Chizuko Nagatsu
Hajime Akutsu
Akio Kiyono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Kaken Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd, Kaken Chemical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP16669880A priority Critical patent/JPS5791993A/en
Publication of JPS5791993A publication Critical patent/JPS5791993A/en
Pending legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

NEW MATERIAL:An antibiotic substance C-22-4A of the antibiotic substance C- 22-4. Appearance: white or light yellow powder. melting point: 205W208°C. Specific rotatory power:[α]D25 -43° (C=0.5, 50% methanol-water). Elementary analysis (%): C, 47.03; H, 6.52; N, 13.56; O, 25.12; Cl, 6.12. Molecular weight; 1,000W2,000. Solubility: soluble in hydrous alcohol and water and insoluble in acetone, ethyl acetate, chloroform, etc.
USE: An antimicrobial agent and water-soluble peptide antibiotic.
PROCESS: A microorganism, belonging to the genus Streptomyces, and having the ability to produce the antibiotic sustance C-22-4, (FERM-P No.5748), is cultivated in a fermenter at 25W35°C by the spinner culture method with aeration, and the aimed substance is adsorbed from the filtrate with "DiaionHP-20", etc. The substance is then eluted with equeous acetone, and purified to give the aimed antibiotic substance C-22-4.
COPYRIGHT: (C)1982,JPO&Japio
JP16669880A 1980-11-28 1980-11-28 Novel antibiotic substance, its preparation and microorganism capable of producing the same Pending JPS5791993A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16669880A JPS5791993A (en) 1980-11-28 1980-11-28 Novel antibiotic substance, its preparation and microorganism capable of producing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16669880A JPS5791993A (en) 1980-11-28 1980-11-28 Novel antibiotic substance, its preparation and microorganism capable of producing the same

Publications (1)

Publication Number Publication Date
JPS5791993A true JPS5791993A (en) 1982-06-08

Family

ID=15836082

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16669880A Pending JPS5791993A (en) 1980-11-28 1980-11-28 Novel antibiotic substance, its preparation and microorganism capable of producing the same

Country Status (1)

Country Link
JP (1) JPS5791993A (en)

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