JPS59134790A - ピリミドン誘導体 - Google Patents

ピリミドン誘導体

Info

Publication number
JPS59134790A
JPS59134790A JP58243046A JP24304683A JPS59134790A JP S59134790 A JPS59134790 A JP S59134790A JP 58243046 A JP58243046 A JP 58243046A JP 24304683 A JP24304683 A JP 24304683A JP S59134790 A JPS59134790 A JP S59134790A
Authority
JP
Japan
Prior art keywords
pyridyl
methyl
oxo
general formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP58243046A
Other languages
English (en)
Japanese (ja)
Inventor
ロバ−ト・ジヨン・アイフ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of JPS59134790A publication Critical patent/JPS59134790A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP58243046A 1982-12-23 1983-12-22 ピリミドン誘導体 Pending JPS59134790A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8236636 1982-12-23
GB8236636 1982-12-23

Publications (1)

Publication Number Publication Date
JPS59134790A true JPS59134790A (ja) 1984-08-02

Family

ID=10535200

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58243046A Pending JPS59134790A (ja) 1982-12-23 1983-12-22 ピリミドン誘導体

Country Status (10)

Country Link
US (2) US4548940A (cs)
EP (1) EP0112707B1 (cs)
JP (1) JPS59134790A (cs)
AU (1) AU2274583A (cs)
DE (1) DE3374313D1 (cs)
DK (1) DK590383A (cs)
ES (1) ES528304A0 (cs)
GR (1) GR79741B (cs)
PT (1) PT77860B (cs)
ZA (1) ZA839536B (cs)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06100446A (ja) * 1990-10-15 1994-04-12 Merck & Co Inc （Ｓ）−α−フルオロメチル−ヒスチジン及びそのエステルを使用するぜん息の治療方法

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1286297C (en) * 1985-06-13 1991-07-16 George S. Sach Pyridine derivatives
GB8601816D0 (en) * 1986-01-25 1986-02-26 Smith Kline French Lab Pyridine derivatives
US6245774B1 (en) 1994-06-21 2001-06-12 Celltech Therapeutics Limited Tri-substituted phenyl or pyridine derivatives
US5786354A (en) * 1994-06-21 1998-07-28 Celltech Therapeutics, Limited Tri-substituted phenyl derivatives and processes for their preparation
GB9412573D0 (en) * 1994-06-22 1994-08-10 Celltech Ltd Chemical compounds
GB9412571D0 (en) 1994-06-22 1994-08-10 Celltech Ltd Chemical compounds
GB9523675D0 (en) 1995-11-20 1996-01-24 Celltech Therapeutics Ltd Chemical compounds
GB9622363D0 (en) 1996-10-28 1997-01-08 Celltech Therapeutics Ltd Chemical compounds
GB9705361D0 (en) 1997-03-14 1997-04-30 Celltech Therapeutics Ltd Chemical compounds
GB9713087D0 (en) * 1997-06-20 1997-08-27 Celltech Therapeutics Ltd Chemical compounds
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
KR100581199B1 (ko) 1998-06-19 2006-05-17 카이론 코포레이션 글리코겐 신타제 키나제 3의 억제제
GB9914258D0 (en) 1999-06-18 1999-08-18 Celltech Therapeutics Ltd Chemical compounds
GB9924862D0 (en) 1999-10-20 1999-12-22 Celltech Therapeutics Ltd Chemical compounds
KR100874791B1 (ko) * 2001-05-29 2008-12-18 바이엘 쉐링 파마 악티엔게젤샤프트 Ｃｄｋ-억제 피리미딘, 그의 제조방법 및 약제로서의 용도
CN106946769B (zh) * 2017-04-16 2019-04-02 内蒙古佳瑞米精细化工有限公司 一种2-氟-5-三氟甲基吡啶的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3535328A (en) * 1967-09-01 1970-10-20 Exxon Research Engineering Co Certain substituted aminothioethoxy pyridines
US3553292A (en) * 1968-12-10 1971-01-05 Grace W R & Co Product and a method of improving the shelf life of uncured polyesters
US4218452A (en) * 1975-10-02 1980-08-19 Smith Kline & French Laboratories Limited Substituted 4-pyrimidone compounds, compositions and methods of use
US4154834A (en) * 1975-12-29 1979-05-15 Smith Kline & French Laboratories Limited Substituted isocytosines having histamine H2 -antagonist activity
ZW21281A1 (en) * 1980-10-01 1981-11-18 Smith Kline French Lab Amine derivatives
US4405790A (en) * 1982-04-08 1983-09-20 Reilly Tar & Chemical Corp. Process for preparing 2-alkylamino- and 2-amino-5-alkylpyridines
JO1279B1 (en) * 1982-12-23 1985-04-20 جون ايف روبرت Pyridine derivatives
DE3375574D1 (en) * 1982-12-23 1988-03-10 Smith Kline French Lab Pyridine derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06100446A (ja) * 1990-10-15 1994-04-12 Merck & Co Inc （Ｓ）−α−フルオロメチル−ヒスチジン及びそのエステルを使用するぜん息の治療方法

Also Published As

Publication number Publication date
US4548940A (en) 1985-10-22
EP0112707A3 (en) 1985-09-25
GR79741B (cs) 1984-10-31
DK590383A (da) 1984-06-24
EP0112707A2 (en) 1984-07-04
DK590383D0 (da) 1983-12-21
US4652650A (en) 1987-03-24
EP0112707B1 (en) 1987-11-04
AU2274583A (en) 1984-06-28
PT77860A (en) 1984-01-01
ZA839536B (en) 1985-02-27
ES8506646A1 (es) 1985-08-01
PT77860B (en) 1986-04-16
DE3374313D1 (de) 1987-12-10
ES528304A0 (es) 1985-08-01

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