JPS60128367A - 血液、尿等中の薬物自動抽出方法 - Google Patents

血液、尿等中の薬物自動抽出方法

Info

Publication number: JPS60128367A
Authority: JP; Japan
Prior art keywords: liquid; adsorption column; column; needle; urine
Prior art date: 1983-12-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP23623083A

Other languages

English (en)

Japanese (ja)

Other versions

JPH0369068B2 (de

Inventor

Yuji Nakahara

雄二中原

Hachiro Nagata

永田　八郎

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

KEISATSUCHIYOU KAGAKU KEISATSU KENKYUSHO

KYOWA SEIMITSU KK

Original Assignee

KEISATSUCHIYOU KAGAKU KEISATSU KENKYUSHO

KYOWA SEIMITSU KK

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-12-16

Filing date

1983-12-16

Publication date

1985-07-09

1983-12-16 Application filed by KEISATSUCHIYOU KAGAKU KEISATSU KENKYUSHO, KYOWA SEIMITSU KK filed Critical KEISATSUCHIYOU KAGAKU KEISATSU KENKYUSHO

1983-12-16 Priority to JP23623083A priority Critical patent/JPS60128367A/ja

1985-07-09 Publication of JPS60128367A publication Critical patent/JPS60128367A/ja

1991-10-30 Publication of JPH0369068B2 publication Critical patent/JPH0369068B2/ja

Status Granted legal-status Critical Current

Links

210000002700 urine Anatomy 0.000 title claims abstract description 13
239000008280 blood Substances 0.000 title claims abstract description 12
210000004369 blood Anatomy 0.000 title claims abstract description 12
238000000605 extraction Methods 0.000 title claims abstract description 12
239000012907 medicinal substance Substances 0.000 title abstract 5
239000007788 liquid Substances 0.000 claims abstract description 49
238000001179 sorption measurement Methods 0.000 claims abstract description 26
238000004140 cleaning Methods 0.000 claims abstract description 14
238000002347 injection Methods 0.000 claims abstract description 11
239000007924 injection Substances 0.000 claims abstract description 11
239000003463 adsorbent Substances 0.000 claims abstract description 7
230000001172 regenerating effect Effects 0.000 claims abstract description 7
239000003814 drug Substances 0.000 claims description 18
229940079593 drug Drugs 0.000 claims description 18
238000010828 elution Methods 0.000 claims description 10
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 9
238000005406 washing Methods 0.000 claims description 8
WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims description 6
230000002378 acidificating effect Effects 0.000 claims description 4
-1 octadecyl silica Chemical compound 0.000 claims description 4
VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
239000000377 silicon dioxide Substances 0.000 claims description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
230000001476 alcoholic effect Effects 0.000 claims description 2
210000003141 lower extremity Anatomy 0.000 claims description 2
OVARTBFNCCXQKS-UHFFFAOYSA-N propan-2-one;hydrate Chemical compound O.CC(C)=O OVARTBFNCCXQKS-UHFFFAOYSA-N 0.000 claims description 2
238000000034 method Methods 0.000 abstract description 11
238000000956 solid--liquid extraction Methods 0.000 abstract description 3
238000007599 discharging Methods 0.000 abstract 1
238000000622 liquid--liquid extraction Methods 0.000 description 4
230000008929 regeneration Effects 0.000 description 4
238000011069 regeneration method Methods 0.000 description 4
238000000638 solvent extraction Methods 0.000 description 4
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
238000010586 diagram Methods 0.000 description 2
239000000243 solution Substances 0.000 description 2
241000255789 Bombyx mori Species 0.000 description 1
PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
150000003943 catecholamines Chemical class 0.000 description 1
238000011109 contamination Methods 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
238000004945 emulsification Methods 0.000 description 1
230000002209 hydrophobic effect Effects 0.000 description 1
239000003326 hypnotic agent Substances 0.000 description 1
230000000147 hypnotic effect Effects 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
240000004308 marijuana Species 0.000 description 1
239000004081 narcotic agent Substances 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
229940094443 oxytocics prostaglandins Drugs 0.000 description 1
239000000575 pesticide Substances 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
150000003180 prostaglandins Chemical class 0.000 description 1
238000000926 separation method Methods 0.000 description 1
239000002904 solvent Substances 0.000 description 1
150000003431 steroids Chemical class 0.000 description 1
239000000021 stimulant Substances 0.000 description 1
239000000126 substance Substances 0.000 description 1
239000003204 tranquilizing agent Substances 0.000 description 1
230000002936 tranquilizing effect Effects 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Physics & Mathematics (AREA)
Food Science & Technology (AREA)
Biochemistry (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Analytical Chemistry (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Immunology (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Automatic Analysis And Handling Materials Therefor (AREA)
Extraction Or Liquid Replacement (AREA)

JP23623083A 1983-12-16 1983-12-16 血液、尿等中の薬物自動抽出方法 Granted JPS60128367A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP23623083A JPS60128367A (ja)	1983-12-16	1983-12-16	血液、尿等中の薬物自動抽出方法

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP23623083A JPS60128367A (ja)	1983-12-16	1983-12-16	血液、尿等中の薬物自動抽出方法

Publications (2)

Publication Number	Publication Date
JPS60128367A true JPS60128367A (ja)	1985-07-09
JPH0369068B2 JPH0369068B2 (de)	1991-10-30

Family

ID=16997717

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP23623083A Granted JPS60128367A (ja)	1983-12-16	1983-12-16	血液、尿等中の薬物自動抽出方法

Country Status (1)

Country	Link
JP (1)	JPS60128367A (de)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5042895A (de) *	1973-08-20	1975-04-18

1983
- 1983-12-16 JP JP23623083A patent/JPS60128367A/ja active Granted

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5042895A (de) *	1973-08-20	1975-04-18

Also Published As

Publication number	Publication date
JPH0369068B2 (de)	1991-10-30

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